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AT2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Androgen Receptor (1) Angiotensin Receptor (11) Fluorescent Dye (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (6) Endocrinology (4) Metabolic Disease (2) Neurological Disease (2)

13

Inhibitors & Agonists

1

Fluorescent Dye

2

Peptides

2

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Buloxibutid 4 Publications Verification AT2 receptor agonist C21	Angiotensin Receptor	Cardiovascular Disease Endocrinology
Buloxibutid (AT2 receptor agonist C21) is a agentlike selective *angiotensin II AT2* receptor agonist with K_i** values of 0.4 nM and >10 μM for the AT2 receptor and AT1 receptor, respectively .

PD 123319 ditrifluoroacetate Maximum Cited Publications 9 Publications Verification	Angiotensin Receptor	Cardiovascular Disease Endocrinology
PD 123319 (ditrifluoroacetate) is a potent, selective AT2 angiotensin II receptor antagonist with IC₅₀ of 34 nM.

AT2 receptor ligand-1	Angiotensin Receptor	Cardiovascular Disease
AT2 receptor ligand-1(compound 14) is a potent *angiotensin AT2* receptor ligand with the K_i 4.9 nM. AT2 receptor ligand-1 shows high stability in microsomes of the sulfonamide ligands .**

AT2R antagonist 1	Angiotensin Receptor	Others
AT2R antagonist 1 (compound 21) is a potent and high selective *AT2R* (angiotensin II AT2 receptor) ligand. AT2R antagonist 1 exhibits a fair *AT2R* affinity, with a K_i of 29 nM. AT2R antagonist 1 also inhibits common agent-metabolizing CYP enzymes. AT2R antagonist 1 shows high stability in human, rat and mouse liver microsomes .

Novokinin	Angiotensin Receptor	Metabolic Disease
Novokinin is a peptide agonist of the *angiotensin AT2* receptor** .

Novokinin TFA	Angiotensin Receptor	Metabolic Disease
Novokinin TFA is a peptide agonist of the *angiotensin AT2* receptor** .

L-162313	Angiotensin Receptor	Cardiovascular Disease
L-162313 is a non-peptide *angiotensin II AT1 and AT2* receptor agonist, with IC₅₀** values of 1.1 and 2.0 nM for AT1 and AT2 receptor, respectively. L-162313 can be used for the research of vasoconstriction, aldosterone release, and cardiovascular growth .

PD 123319 (S)-(+)-PD 123319	Angiotensin Receptor	Cardiovascular Disease Endocrinology
PD 123319 (ditrifluoroacetate) is a potent, selective AT2 angiotensin II receptor antagonist with IC₅₀ of 34 nM.

PD 123177	Angiotensin Receptor	Cardiovascular Disease
PD 123177 is a nonpeptide antagonist specific for *angiotensin II (AII) subtype AT2* receptor** in mammalian systems .

rac-Olodanrigan rac-EMA401; rac-PD-126055; EMA400	Angiotensin Receptor	Neurological Disease
rac-Olodanrigan (rac-EMA401; EMA400) is a racemic mixture of the S-enantiomer (EMA401; HY-13106) and R-enantiomer (EMA402). rac-Olodanrigan is a potent and selective AT₂ receptor antagonist with IC₅₀s of 75.2 nM and 2918 nM for AT₂R and AT₁R, respectively. rac-Olodanrigan evokes dose-dependent relief of mechanical allodynia in the ipsilateral hind paws of rats with a chronic constriction injury (CCI) of the sciatic nerve .

CGP-42112 2 Publications Verification CGP42112A	Angiotensin Receptor	Neurological Disease Endocrinology
CGP-42112 (CGP-42112A) is a potent Angiotensin-II subtype 2 receptor(AT2 R) agonist .

Androgen receptor antagonist 4	Androgen Receptor	Cancer
Androgen receptor antagonist 4 (Compound AT2) is an androgen receptor (AR) antagonist with an IC₅₀ of 0.15 μM. Androgen receptor antagonist 4 efficiently antagonizes AR transcriptional activity, suppresses downstream target gene of AR, and blocks the DHT-induced AR nuclear translocation. Androgen receptor antagonist 4 shows anticancer activities .

Green DND-26 1 Publications Verification	Fluorescent Dye	Others
Green DND-26 is a green fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 504/511 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and generally gather on spherical organelles. Green DND-26 is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .

Cat. No.	Product Name	Type

Green DND-26 1 Publications Verification	Fluorescent Dyes/Probes
Green DND-26 is a green fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 504/511 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and generally gather on spherical organelles. Green DND-26 is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .

Cat. No.	Product Name	Target	Research Area

Novokinin	Angiotensin Receptor	Metabolic Disease
Novokinin is a peptide agonist of the *angiotensin AT2* receptor** .

Novokinin TFA	Angiotensin Receptor	Metabolic Disease
Novokinin TFA is a peptide agonist of the *angiotensin AT2* receptor** .

Cat. No.	Compare	Product Name	Application	Reactivity

	AGTR2 Antibody (YA3090) AGTR2; Angiotensin ii receptor type 2; Angiotensin II type-2 receptor; AT2 receptor; AT2; AT2r; MRX88; Angiotensin ii AT2; Angiotensin receptor 2; Type-2 angiotensin II receptor; ATGR2	WB, IP	Human, Mouse, Rat
	AGTR2 Antibody (YA3090) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3090), targeting AGTR2, with a predicted molecular weight of 41 kDa (observed band size: 41 kDa). AGTR2 Antibody (YA3090) can be used for WB, IP experiment in human, mouse, rat background.

	Angiotensin II Type 1 Receptor Antibody (YA3358) AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B; Type-1 angiotensin II receptor; AT1AR; AT1BR; Angiotensin II type-1 receptor; AT1	WB	Human
	Angiotensin II Type 1 Receptor Antibody (YA3358) is a biotin-conjugated non-conjugated IgG antibody, targeting Angiotensin II Type 1 Receptor, with a predicted molecular weight of 41 kDa (observed band size: 41 kDa). Angiotensin II Type 1 Receptor Antibody (YA3358) can be used for WB experiment in human background.

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