Anesthetic compound

By Targets:	Adrenergic Receptor (1) Antibiotic (1) Apoptosis (1) Bacterial (1) Endogenous Metabolite (1) Fungal (1) GABA Receptor (1) iGluR (1) MMP (1) NF-κB (1) Sodium Channel (1)
By Research Areas:	Cancer (1) Infection (2) Inflammation/Immunology (2) Neurological Disease (6)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0900

Anethole 1 Publications Verification Anise camphor; p-Propenylanisole; Isoestragole	Apoptosis Fungal Bacterial MMP NF-κB	Infection Neurological Disease Inflammation/Immunology Cancer
Anethole is a type of orally active aromatic compound that is widely found in nature and used as a flavoring agent. Anethole possesses anticancer, anti-inflammatory, antioxidant, antibacterial, antifungal, anesthetic, estrogenic, central nervous system depressant, hypnotic, insecticidal, and gastroprotective effects. Anethole can be used in the study of oxidative stress-related skin diseases and prostate cancer .

HY-121891

Rhinocaine	Others	Others
Rhinocaine is a compound with local anesthetic activity.

HY-122050

Oe-9000	Sodium Channel	Neurological Disease
Oe-9000 is a compound with local anesthetic activity that inhibits voltage-gated Na ⁺ currents in neurons, including both TTX-resistant and TTX-sensitive currents, with effects superior to those of some other local anesthetics.

HY-121391

Hedonal	Others	Others
Hedonal is a compound with anesthetic activity. In related research in Russia, it has a certain development history in experimental and clinical applications, and is of great significance to the development of anesthesiology.

HY-106495

Vadocaine OR K-242	Adrenergic Receptor	Neurological Disease
Vadocaine (OR K-242), an orally active antitussive compound, is a local agent that can suppress or relieve pain .

HY-156061

NAP-1	GABA Receptor	Neurological Disease Inflammation/Immunology
NAP-1 is a compound with agent that can suppress or relieve pain. effects. NAP-1 enhances the inhibitory current by binding to a specific site of GABAaR, resulting in a narcotic effect. NAP-1 can be used in research to develop clinical agent that can suppress or relieve pain .

HY-114987

EMD 21657	iGluR	Neurological Disease
EMD 21657 is a derivative of Piracetam (HY-B0585). EMD 21657 inhibits LOT compound action potential, and enhances the local anesthetic effect of Hexanol (HY-W032022). EMD 21657 exhibits hemolytic effect, and can be used in research about alcoholic encephalopathy syndrome .

HY-121886

Bucricaine	Endogenous Metabolite	Neurological Disease
Bucricaine is an anesthetic compound with analgesic activity. Bucricaine is used in clinical anesthesia to reduce pain during surgery. The mechanism of action of Bucricaine involves inhibition of nerve signaling. Bucricaine's applications include local anesthesia and dental anesthesia. Bucricaine is widely used during surgery and other medical procedures to improve patient comfort .

HY-114735

Mandelonitrile benzoate	Antibiotic	Infection
Mandelonitrile benzoate is a defensive secretion of millipedes that releases other chemicals during the cyanidation process in addition to hydrocyanic acid (HCN) and benzaldehyde. Several families of millipedes, including Polydesmidae, Paradoxosomatidae, and Euryuridae, have been shown to secrete phenols and guaiaeol, with one Paradoxosomatid also producing ethylbenzoic acid and benzoic acid. In addition, members of the Xystodesmidae family commonly produce three compounds: benzoic acid, mandelonitrile benzoate, and benzoyl cyanide. Benzoyl cyanide has not been previously discovered as a natural product. These additional natural products are discussed as defensive antipredator and antibiotic agents. Benzoyl cyanide appears to have anesthetic properties for some predators. The study provides a preliminary chemotaxonomic basis for distinguishing various taxonomic groups of millipedes.

Cat. No.	Product Name

HY-L071

Alkaloids Library	565 compounds
Alkaloids are a large and complex group of cyclic compounds that contain N. About 2,000 different alkaloids have been isolated. Important alkaloids include morphine, strychnine, atropine, colchicine, ephedrine, quinine, and nicotine. Alkaloids are useful as diet ingredients, supplements, and pharmaceuticals, in medicine and in other applications in human life. They showed anti-inflammatory, anticancer, analgesics, local anesthetic and pain relief, neuropharmacologic, antimicrobial, antifungal, and many other activities. Alkaloids are also important compounds in organic synthesis for searching new semisynthetic and synthetic compounds with possibly better biological activity than parent compounds. MCE designs a unique collection of 565 alkaloids that all come from natural products. MCE Alkaloids Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

Alkaloids Library

565 compounds

Alkaloids are a large and complex group of cyclic compounds that contain N. About 2,000 different alkaloids have been isolated. Important alkaloids include morphine, strychnine, atropine, colchicine, ephedrine, quinine, and nicotine. Alkaloids are useful as diet ingredients, supplements, and pharmaceuticals, in medicine and in other applications in human life. They showed anti-inflammatory, anticancer, analgesics, local anesthetic and pain relief, neuropharmacologic, antimicrobial, antifungal, and many other activities. Alkaloids are also important compounds in organic synthesis for searching new semisynthetic and synthetic compounds with possibly better biological activity than parent compounds.

MCE designs a unique collection of 565 alkaloids that all come from natural products. MCE Alkaloids Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0900

Anethole 1 Publications Verification Anise camphor; p-Propenylanisole; Isoestragole	Structural Classification Classification of Application Fields Source classification Plants Microorganisms Simple Phenylpropanols Leguminosae Phenylpropanoids Umbelliferae Vernonia Schreb. Glycyrrhiza uralensis Fisch. Disease Research Fields Cancer	Apoptosis Fungal Bacterial MMP NF-κB
Anethole is a type of orally active aromatic compound that is widely found in nature and used as a flavoring agent. Anethole possesses anticancer, anti-inflammatory, antioxidant, antibacterial, antifungal, anesthetic, estrogenic, central nervous system depressant, hypnotic, insecticidal, and gastroprotective effects. Anethole can be used in the study of oxidative stress-related skin diseases and prostate cancer .

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
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Anesthetic compound

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