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Results for "

Bag3

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Recombinant Proteins

1

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-156278
    FB49

    		Apoptosis Autophagy Cancer
    FB49 is a highly selective inhibitor of Bcl-2-associated athanogene 3 (BAG3), with the Ki of 45 μM. FB49 inhibits the cell growth in human tumoral cells, but has no toxicity in human peripheral mononuclear cells. FB49 block cell cycle in G1 phase and to induce apoptosis as well as autophagy in medulloblastoma HD-MB03 treated cells .
    FB49
  • HY-124611
    JG-231

    		HSP Cancer
    JG-231 is an analogue of JG-98 with anticancer effects. JG-231 inhibits the interaction of Hsp70-BAG3. JG-231 inhibits MDA-MB-231 heterograft tumor models of triple negative breast cancer (TNBC) .
    JG-231
  • HY-117282
    JG-98
    5+ Cited Publications

    		 HSP Apoptosis Cancer
    JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction. JG-98 shows anti-cancer activities affecting both cancer cells and tumor-associated macrophages [3].
    JG-98
  • HY-RS01344
    BAG3 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    BAG3 Human Pre-designed siRNA Set A contains three designed siRNAs for BAG3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    BAG3 Human Pre-designed siRNA Set A
    BAG3 Human Pre-designed siRNA Set A

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