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HaloPROTAC-E

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145752
    HaloPROTAC-E
    1 Publications Verification

    		 PROTACs SGK Autophagy Cancer
    HaloPROTAC-E is a potent Halo PROTAC degrader that reversibly induces degradation of two Halo-tagged endoplasmic reticulum-localized proteins, SGK3 and VPS34, with a DC50 of 3-10 nM. HaloPROTAC-E significantly and selectively induces degradation of endogenous VPS34 complexes (VPS34, VPS15, Beclin1, and ATG14) labeled with Halo and inhibits autophagy.
    HaloPROTAC-E
  • HY-W613607
    HO-PEG3-(CH2)6-Cl

    		PROTAC Linkers Cancer
    HO-PEG3-(CH2)6-Cl is a PROTAC linker that can be used to synthesize HaloPROTAC-E (HY-145752) .
    HO-PEG3-(CH2)6-Cl

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