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INK4C-IN-2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108420
    INK4C-IN-2
    1 Publications Verification

    CDK Cancer
    INK4C-IN-2 (Compound 40) is the inhibitor for INK4C (also known as p18) and the activator for CDK4/6. INK4C-IN-2 increases the number and expansion capacity of mouse and human hematopoietic stem cells (HSCs) with EC50 of 5.21 nM, promotes the self-renewal and multilineage differentiation of HSCs. INK4C-IN-2 improves the expansion and long-term hematopoietic reconstruction ability of HSCs in mouse bone marrow transplantation model .
    INK4C-IN-2

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