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Insecticidal agent-19

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-168918
    Insecticidal agent 19

    		Parasite Dihydrofolate reductase (DHFR) Infection
    Insecticidal agent 19 (Compound 7b) exhibits antimalarial activity by inhibiting dihydrofolate reductase-thymidylate synthase (DHFR-TS) and pteridine reductase 1 (PTR1) through the folic acid metabolic pathway. Insecticidal agent 19 inhibits Leishmania major promastigote and amastigote with IC50 of 1.43 μM and 3.78 μM .
    Insecticidal agent 19

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