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JH-FK-08

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-170616
    JH-FK-08

    		Fungal Interleukin Related Infection Inflammation/Immunology
    JH-FK-08 is an inhibitor for the serine/threonine-specific phosphatase calcineurin. JH-FK-08 exhibits antifungal activity that inhibits C. neoformans with MIC80 of 0.8 µg/mL. JH-FK-08 exhibits immunosuppressive activity and inhibits the IL-2 expression with an IC50 of 42.6 nM. JH-FK-08 exhibits anti-infectious activity in mouse models .
    JH-FK-08

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