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Results for "

MEIS1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Epigenetic Reader Domain (1) Histone Demethylase (1) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (5) Cardiovascular Disease (1)
Oligonucleotides:	Pre-designed siRNA Sets (2) siRNAs (2)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

MEISi-1	Others	Cardiovascular Disease Others Cancer
MEISi-1 is a homeodomain inhibitor of small molecule *MEIS1* protein. MEISi-1 significantly inhibited the activity of luciferase reporter genes containing MEIS binding sites (TGACAG) and induced self-renewal of mouse and human HSCS in vitro and in vivo. MEISi-1 can be used for research in blood diseases, heart regeneration and cancer ^[1].

CCI-007	Apoptosis	Cancer
CCI-007 is a small molecule with cytotoxic activity against infant leukemia with MLL rearrangements, with IC₅₀ values of 2.5-6.2 μM in sensitive cells ^[1].

MEISi-2	Others	Cancer
MEISi-2 is a selective inhibitor of MEIS, a key regulator of hematopoietic stem cell (HSC) self-renewal. MEISi-2 is developed for the research of cardiac injuries, hematopoiesis issues, bone marrow transplantations, and cancer ^[1].

MEIS1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MEIS1 Human Pre-designed siRNA Set A contains three designed siRNAs for MEIS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MEIS1 Human Pre-designed siRNA Set A MEIS1 Human Pre-designed siRNA Set A

MEIS-IN-2	Others	Others
MEIS-IN-2 is a myeloid ecotropic viral integration site 1 (MEIS1) inhibitor.

FY-21	Histone Demethylase	Cancer
FY-21 is a selective inhibitor of *LSD1* (IC₅₀=340 nM), with anti-proliferation and anti-colony formation activities. FY-21 enhances p53 expression, down-regulates HOXA9 and MEIS1 expression. FY-21 also induces leukemia cell differentiation to exhibts antitumor activity ^[1].

BAY-155	Epigenetic Reader Domain	Cancer
BAY-155 is a potent and selective menin-MLL tool inhibitor, with an IC₅₀ of 8 nM. BAY-155 leads to a strong expression down-regulation of the MEIS1 gene and up-regulation of CD11b and MNDA genes. BAY-155 shows anti-proliferative effects in AML/ALL (acute myeloid/lymphoblastic leukemia) models ^[1].

MEI1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MEI1 Human Pre-designed siRNA Set A contains three designed siRNAs for MEI1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MEI1 Human Pre-designed siRNA Set A MEI1 Human Pre-designed siRNA Set A

Cat. No.	Compare	Product Name	Application	Reactivity

	MEIS1 Antibody (YA2438) Homeo box protein MEIS1; Leukemogenic homolog protein; MEIS 1; MEIS homeo box 1; MEIS1; MEIS1 mouse homolog; MEIS1 protein	WB, IP, FC	Human, Mouse, Rat
	MEIS1 Antibody (YA2438) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2438), targeting MEIS1, with a predicted molecular weight of 43 kDa (observed band size: 47 kDa). MEIS1 Antibody (YA2438) can be used for WB, IP, FC experiment in human, mouse, rat background.

	MEIS2 Antibody (YA1778) MEIS homeobox 2; MEIS1 related gene 1; MEIS2; MGC2820; MRG1	WB, FC	Human, Mouse, Rat
	MEIS2 Antibody (YA1778) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1778), targeting MEIS2, with a predicted molecular weight of 52 kDa (observed band size: 52 kDa). MEIS2 Antibody (YA1778) can be used for WB, FC experiment in human, mouse, rat background.

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MEIS1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
MEIS1 Human Pre-designed siRNA Set A contains three designed siRNAs for MEIS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MEI1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
MEI1 Human Pre-designed siRNA Set A contains three designed siRNAs for MEI1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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