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Results for "

NKT Agonist

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Fluorescent Dye

1

Biochemical Assay Reagents

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-102022
    α-Galactosylceramide
    2 Publications Verification

    α-GalCer; KRN7000

    		 Transmembrane Glycoprotein Interleukin Related Inflammation/Immunology Cancer
    α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. α-Galactosylceramide is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide plus CD1d binds the NKT cell TCR (T cell antigen receptor) .
    α-Galactosylceramide
  • HY-156997
    ABX196

    		Others Others
    ABX196 is NKT agonist. ABX196 is an analog of the parental compound -GalCer .
    ABX196
  • HY-162727
    GCS-12

    		IFNAR Interleukin Related Inflammation/Immunology Cancer
    GCS-12 is a Th1/2-balanced sulfonamide glycolipid with improved interaction with CD1d. GCS-12 is an agonist for natural killer T (NKT) cell, that induces the secretion of cytokine IFN-γ and IL-4, and exhibits immunomodulatory and anti-tumor activities in mice .
    GCS-12
  • HY-162726
    GCS-11

    		Interleukin Related Cancer
    GCS-11 is a powerful natural killer T (NKT) cell agonist. It boosts the production of IFN-γ and IL-4, with a particular selectivity for IFN-γ. GCS-11 exhibits anticancer activity. GCS-11 has the potential for research into cancer immunotherapies or vaccine development as a promising adjuvant .
    GCS-11
  • HY-102022G
    α-Galactosylceramide

    α-GalCer; KRN7000

    		 Interleukin Related Transmembrane Glycoprotein Inflammation/Immunology Cancer
    α-Galactosylceramide (α-GalCer) (GMP) is a GMP-grade α-Galactosylceramide (HY-102022). Small molecules of GMP grade can be used as adjuvant reagents in cell therapy. α-Galactosylceramide (GMP) can activate iNKT cells in vitro, characterized by rapid secretion of IL-4 and IFN-γ, transient downregulation of cell-surface TCR, clonal expansion and homeostatic contraction. α-Galactosylceramide is a very potent NKT cell agonist and binds effectively to CD1d .
    α-Galactosylceramide

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