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Nicotinamide (Standard)

" in MedChemExpress (MCE) Product Catalog:

8

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5

Natural
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0150R
    Nicotinamide (Standard)
    55+ Cited Publications

    Niacinamide(Standard); Nicotinic acid amide (Standard)

    		 Endogenous Metabolite Sirtuin Cancer
    Nicotinamide (Standard) is the analytical standard of Nicotinamide. This product is intended for research and analytical applications. Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity .
    Nicotinamide (Standard)
  • HY-113432R
    Nudifloramide (Standard)

    2PY (Standard)

    		 Endogenous Metabolite PARP Metabolic Disease
    Nudifloramide (Standard) is the analytical standard of Nudifloramide. This product is intended for research and analytical applications. Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro .
    Nudifloramide (Standard)
  • HY-101407R
    Nicotinamide N-oxide (Standard)

    		CXCR Drug Metabolite Endogenous Metabolite Inflammation/Immunology Endocrinology
    Nicotinamide N-oxide (Standard) is the analytical standard of Nicotinamide N-oxide. This product is intended for research and analytical applications. Nicotinamide N-oxide, an in vivo nicotinamide metabolite, is a potent, and selective antagonist of the CXCR2 receptor.
    Nicotinamide N-oxide (Standard)
  • HY-123033AR
    Nicotinamide riboside chloride (Standard)

    		Sirtuin Endogenous Metabolite Neurological Disease Metabolic Disease Cancer
    Nicotinamide riboside (chloride) (Standard) is the analytical standard of Nicotinamide riboside (chloride). This product is intended for research and analytical applications. Nicotinamide riboside Chloride, an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3. Nicotinamide riboside Chloride is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities[1]. Nicotinamide riboside Chloride reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease[2].
    Nicotinamide riboside chloride (Standard)
  • HY-F0004R
    β-Nicotinamide mononucleotide (Standard)

    		Endogenous Metabolite Neurological Disease Cancer
    Zimelidine (dihydrochloride) (Standard) is the analytical standard of Zimelidine (dihydrochloride). This product is intended for research and analytical applications. Zimelidine dihydrochloride is a potent and selective inhibitor of serotonin 5-HT uptake and SERT. Zimelidine dihydrochloride is an antidepressant .
    β-Nicotinamide mononucleotide (Standard)
  • HY-B0341R
    Nicorandil (Standard)

    		Potassium Channel Cardiovascular Disease
    Nicorandil (Standard) is the analytical standard of Nicorandil. This product is intended for research and analytical applications. Nicorandil (SG-75) is a potent potassium channel activator and targets vascular nucleoside diphosphate-dependent K + channels and cardiac ATP-sensitive K + channels (KATP). Nicorandil is a nicotinamide ester with vasodilatory and cardioprotective effects and has the potential for angina and forischemic heart diseases .
    Nicorandil (Standard)
  • HY-10079R
    CHS-828 (Standard)

    GMX1778 (Standard)

    		 NAMPT Apoptosis Cancer
    CHS-828 (Standard) is the analytical standard of CHS-828. This product is intended for research and analytical applications. CHS-828 (GMX1778) is a competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), with an IC50 less than 25 nM. CHS-828 (GMX1778) exerts a cytotoxic effect by decreasing the cellular level of NAD+ and exhibits a potent anticancer activity[1].
    CHS-828 (Standard)
  • HY-100973AR
    Adenosine 5′-diphosphoribose sodium (Standard)

    ADP ribose sodium (Standard)

    		 TRP Channel Autophagy Metabolic Disease Endocrinology Cancer
    Adenosine 5′-diphosphoribose (sodium) (Standard) is the analytical standard of Adenosine 5′-diphosphoribose (sodium). This product is intended for research and analytical applications. Adenosine 5′-diphosphoribose sodium (ADP ribose sodium) is a nicotinamide adenine nucleotide (NAD+) metabolite. Adenosine 5′-diphosphoribose sodium is the most potent and primary intracellular Ca2+-permeable cation TRPM2 channel activator. Adenosine 5′-diphosphoribose sodium also can enhance autophagy[1][2].
    Adenosine 5′-diphosphoribose sodium (Standard)

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