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Results for "

PCAF Brd

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101125B
    D-Moses

    D-45

    		 Epigenetic Reader Domain Cancer
    D-Moses (D-45) is an enantiomer of L-Moses (HY-101125). L-Moses (L-45) is a potent and selective p300/CBP-associated factor (PCAF) bromodomain (Brd) inhibitor. D-Moses shows no observable binding for PCAF Brd. D-Moses can be used as an inactive control compound to L-Moses .
    D-Moses
  • HY-101125A
    L-Moses dihydrochloride
    2 Publications Verification

    L-45 dihydrochloride

    		 Epigenetic Reader Domain Cancer
    L-Moses (L-45) dihydrochloride is the first potent, selective, and cell-active p300/CBP-associated factor (PCAF) bromodomain (Brd) inhibitor with a Kd of 126 nM .
    L-Moses dihydrochloride
  • HY-101125
    L-Moses
    2 Publications Verification

    L-45

    		 Epigenetic Reader Domain Cancer
    L-Moses (L-45) is the first potent, selective, and cell-active p300/CBP-associated factor (PCAF) bromodomain (Brd) inhibitor with a Kd of 126 nM .
    L-Moses
  • HY-128597
    BRD-IN-3

    		Epigenetic Reader Domain Cancer
    BRD-IN-3 ((R,R)-36n) is a highly potent PCAF bromodomain (BRD) inhibitor, with an IC50 of 7 nM. BRD-IN-3 also exhibits activity against GCN5 and FALZ .
    BRD-IN-3
  • HY-115829
    APA-H-MPO hydrochloride

    		HIV Infection
    APA-H-MPO hydrochloride is an inhibitor of PCAF bromodomain/Tat-AcK50 interaction with potential for anti-HIV/AIDS. APA-H-MPO hydrochloride can effectively inhibit the binding of PCAF bromodomain to Tat-AcK50. APA-H-MPO hydrochloride showed low cytotoxicity in preliminary cell studies. APA-H-MPO hydrochloride is considered a potential candidate for a promising inhibitory strategy targeting the host cell protein PCAF BRD to block HIV replication .
    APA-H-MPO hydrochloride

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