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Results for "

SMARCA2-IN-7

" in MedChemExpress (MCE) Product Catalog:

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-161886
    SMARCA2-IN-7

    		Others Cancer
    SMARCA2-IN-7 (compound 12), a dual inhibitor of BRM and BRG1 (IC50 < 0.005 for both), has an anti-tumor proliferation effect that inhibits BRG1-deleted SKMEL5 tumor proliferation with a cell proliferation activity AAC50 of 13 nM in SKMEL5. The cell proliferation activity AAC50 of KRT880 in H1299 cells was 42 nM .
    SMARCA2-IN-7
  • HY-159544
    SMARCA2 ligand-7

    		Ligands for Target Protein for PROTAC Cancer
    SMARCA2 ligand-7 is a ligand for target protein for pROTAC.
    SMARCA2 ligand-7
  • HY-159451
    PROTAC SMARCA2 degrader-7

    		PROTACs Epigenetic Reader Domain Cancer
    PROTAC SMARCA2 degrader-7 (Compound I-428) is a PROTAC degrader for SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A (SMARCA) SMARCA2. PROTAC SMARCA2 degrader-7 degrades SMARCA2 and SMARCA4 in MV411 with DC50 of <100 and 100-500 nM. (Pink: Ligand for target protein (HY-159542); Black: Linker (HY-159538); Blue: Ligand for E3 ligase (S,R,S)-AHPC (HY-125845))
    PROTAC SMARCA2 degrader-7

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