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TGase2-IN-1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-159962
    TGase2-IN-1

    		Glutaminase Metabolic Disease
    TGase2-IN-1 (Compound 22) is an orally active inhibitor for TGase2 with an IC50 of 1.12 μM. TGase2-IN-1 inhibits TGase2 in human retinal microvascular endothelial cells with an IC50 of 0.07 μM. TGase2-IN-1 exhibits 74.6% oral bioavailability. TGase2-IN-1 inhibits retinal vascular leakage in mouse Streptozotocin (HY-13753)-induced diabetic model .
    TGase2-IN-1

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