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Results for "

acidic hydrolysis

" in MedChemExpress (MCE) Product Catalog:

45

Inhibitors & Agonists

25

Biochemical Assay Reagents

1

Peptides

1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-113441
    4-Hydroxy-3-methoxyphenylglycol sulfate potassium

    MHPG sulfate potassium

    		 Biochemical Assay Reagents Others
    4-Hydroxy-3-methoxyphenylglycol sulfate potassium is a biosynthesis product that releases Na2SO4 and free ethylene glycol on acidic hydrolysis .
    4-Hydroxy-3-methoxyphenylglycol sulfate potassium
  • HY-W133898
    Tryptone

    		Biochemical Assay Reagents Others
    Tryptone is a common component of biological media. Tryptone is the polypeptone derived from the protein hydrolysis of animal tissue (pancreas) and digested by pancreatic enzymes. The main components of Tryptone were the digestion of casein by trypsin, including the peptones, small peptides and amino acids generated from the hydrolysis of casein. Tryptone provides nutrients needed for bacterial growth, especially nitrogen and carbon sources.
    Tryptone
  • HY-P2831
    Esterase, pig liver
    2 Publications Verification

    CESs

    		 Endogenous Metabolite Metabolic Disease
    Esterase, pig liver (CESs), namely carboxylate hydrolases, are widely distributed in nature, commonly found in mammalian liver, and often used in biochemical research. Esterase catalyzes the hydrolysis of a variety of endogenous and exogenous substrates, including esters, thioesters, carbamates, and amides, hydrolyzing carboxylic acid esters to the corresponding alcohols and carboxylic acids .
    Esterase, pig liver
  • HY-Y1422B
    Lipase (MS grade)

    		Endogenous Metabolite Metabolic Disease
    Lipase (MS grade) catalyzes the hydrolysis of triacylglycerols to release long-chain fatty acids in a site-specific manner.
    Lipase (MS grade)
  • HY-Y1422C
    Lipase, Chromobacterium viscosum

    		Endogenous Metabolite Others
    Lipase, Chromobacterium viscosum catalyzes the hydrolysis of ester bonds in lipids into glycerol and fatty acids. Lipase, Chromobacterium viscosum is involved in the digestion of fats and can be used industrially for the production of flavors, pharmaceuticals, and biodiesel .
    Lipase, Chromobacterium viscosum
  • HY-P2736
    Amidase

    		Endogenous Metabolite Metabolic Disease
    Amidases, a member of nitrilase superfamily, catalyzes the hydrolysis of an amide, leading to the formation of carboxylic acid and ammonia. Amidases contain a conserved stretch of approximately 130 amino acids known as the AS sequence, and play a role in important metabolic processes .
    Amidase
  • HY-W717548
    Safinamide acid

    		Drug Metabolite Others
    Safinamide acid (Compound Imp-E) is the metabolite of Safinamide (HY-70057). Safinamide acid can be formed by hydrolysis of Safinamide intermediate under alkaline or acidic conditions. Safinamide acid is utilized to monitor process-related impurities and degradation products in safinamide samples .
    Safinamide acid
  • HY-P2879C
    Cholesterol esterase, schizophyllum commune

    		Endogenous Metabolite Metabolic Disease
    Cholesterol esterase, Schizophyllum commune is an enzyme that catalyzes the hydrolysis of cholesterol esters into free cholesterol and fatty acids, facilitating the absorption of cholesterol in the intestine. Cholesterol esterase, Schizophyllum commune can be used in combination with cholesterol oxidase to measure cholesterol content .
    Cholesterol esterase, schizophyllum commune
  • HY-134019
    Arachidonoyl p-nitroaniline

    		Others Others
    Arachidonoyl p-nitroaniline is a substrate for the hydrolysis of p-nitroaniline by FAAH in Dictyostelium discoideum with long-chain unsaturated fatty acids. Arachidonoyl p-nitroaniline can be used in enzyme kinetic studies. Examples include determining the hydrolysis rate of Arachidonoyl p-nitroaniline and analyzing the fatty acid amide hydrolase activity of recombinant His-FAAH purified from Dictyostelium to characterize the binding and catalytic specificity of mammalian FAAH enzymes .
    Arachidonoyl p-nitroaniline
  • HY-134511
    15(S)-HpEPE

    		Prostaglandin Receptor Inflammation/Immunology Cancer
    15(S)-HpEPE is a product of lipoxygenase hydrolysis of unsaturated fatty acids (PUFA) and is a potential inhibitor of prostaglandin H synthase 2 (PGHS-2). 15(S)-HpEPE can downregulate the expression of PGHS-2 .
    15(S)-HpEPE
  • HY-158362A
    Monoglyceride lipase, Bacillus sp.

    		Endogenous Metabolite Neurological Disease Metabolic Disease Inflammation/Immunology
    Monoglyceride lipase, Bacillus sp., is a key enzyme involved in lipid metabolism. It catalyzes the hydrolysis of monoglycerides (particularly 2-AG, or 2-arachidonoylglycerol) into glycerol and free fatty acids. By regulating the levels of 2-AG, Monoglyceride lipase, Bacillus sp., can influence neural signaling, pain perception, inflammatory responses, and metabolic processes .
    Monoglyceride lipase, Bacillus sp.
  • HY-E70130
    Snailase, Snail gastrointestinal

    		Others Others
    Snailase, Snail gastrointestinal is an enzyme mixture composed of more than 20 enzymes, which is often used for enzymatic hydrolysis of purified flavonoid glycosides. Snailase can be obtained from the digestive tract and includes cellulase, sucrase, hemicellulase, pectinase, polygalacturonase, protease, etc .
    Snailase, Snail gastrointestinal
  • HY-128476
    Sodium Tartrate

    		Others Others
    Sodium Tartrate is a pH-Regulating agent with antioxidant activity. Sodium Tartrate is particularly effective retarding hydrolysis while heating at high temperatures, resulting in increase of acid values (AVs) of vegetable oils .
    Sodium Tartrate
  • HY-167294
    PLLA5000-PEG5000-Thiol

    		Biochemical Assay Reagents Others
    PLLA5000-PEG5000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA5000-PEG5000-Thiol can be used in drug delivery research .
    PLLA5000-PEG5000-Thiol
  • HY-167295
    PLLA5000-PEG3000-Thiol

    		Biochemical Assay Reagents Others
    PLLA5000-PEG3000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA5000-PEG3000-Thiol can be used in drug delivery research .
    PLLA5000-PEG3000-Thiol
  • HY-167296
    PLLA5000-PEG2000-Thiol

    		Biochemical Assay Reagents Others
    PLLA5000-PEG2000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA5000-PEG2000-Thiol can be used in drug delivery research .
    PLLA5000-PEG2000-Thiol
  • HY-167297
    PLLA5000-PEG1000-Thiol

    		Biochemical Assay Reagents Others
    PLLA5000-PEG1000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA5000-PEG1000-Thiol can be used in drug delivery research .
    PLLA5000-PEG1000-Thiol
  • HY-167298
    PLLA4000-PEG5000-Thiol

    		Biochemical Assay Reagents Others
    PLLA4000-PEG5000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA4000-PEG5000-Thiol can be used in drug delivery research .
    PLLA4000-PEG5000-Thiol
  • HY-167299
    PLLA4000-PEG3000-Thiol

    		Biochemical Assay Reagents Others
    PLLA4000-PEG3000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA4000-PEG3000-Thiol can be used in drug delivery research .
    PLLA4000-PEG3000-Thiol
  • HY-167300
    PLLA4000-PEG2000-Thiol

    		Biochemical Assay Reagents Others
    PLLA4000-PEG2000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA4000-PEG2000-Thiol can be used in drug delivery research .
    PLLA4000-PEG2000-Thiol
  • HY-167301
    PLLA4000-PEG1000-Thiol

    		Biochemical Assay Reagents Others
    PLLA4000-PEG1000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA4000-PEG1000-Thiol can be used in drug delivery research .
    PLLA4000-PEG1000-Thiol
  • HY-167302
    PLLA3000-PEG5000-Thiol

    		Biochemical Assay Reagents Others
    PLLA3000-PEG5000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA3000-PEG5000-Thiol can be used in drug delivery research .
    PLLA3000-PEG5000-Thiol
  • HY-167303
    PLLA3000-PEG3000-Thiol

    		Biochemical Assay Reagents Others
    PLLA3000-PEG3000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA3000-PEG3000-Thiol can be used in drug delivery research .
    PLLA3000-PEG3000-Thiol
  • HY-167304
    PLLA3000-PEG2000-Thiol

    		Biochemical Assay Reagents Others
    PLLA3000-PEG2000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA3000-PEG2000-Thiol can be used in drug delivery research .
    PLLA3000-PEG2000-Thiol
  • HY-167305
    PLLA3000-PEG1000-Thiol

    		Biochemical Assay Reagents Others
    PLLA3000-PEG1000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA3000-PEG1000-Thiol can be used in drug delivery research .
    PLLA3000-PEG1000-Thiol
  • HY-167306
    PLLA2000-PEG5000-Thiol

    		Biochemical Assay Reagents Others
    PLLA2000-PEG5000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA2000-PEG5000-Thiol can be used in drug delivery research .
    PLLA2000-PEG5000-Thiol
  • HY-167307
    PLLA2000-PEG3000-Thiol

    		Biochemical Assay Reagents Others
    PLLA2000-PEG3000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA2000-PEG3000-Thiol can be used in drug delivery research .
    PLLA2000-PEG3000-Thiol
  • HY-167308
    PLLA2000-PEG2000-Thiol

    		Biochemical Assay Reagents Others
    PLLA2000-PEG2000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA2000-PEG2000-Thiol can be used in drug delivery research .
    PLLA2000-PEG2000-Thiol
  • HY-167309
    PLLA2000-PEG1000-Thiol

    		Biochemical Assay Reagents Others
    PLLA2000-PEG1000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA2000-PEG1000-Thiol can be used in drug delivery research .
    PLLA2000-PEG1000-Thiol
  • HY-167310
    PLLA1000-PEG5000-Thiol

    		Biochemical Assay Reagents Others
    PLLA1000-PEG5000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA1000-PEG5000-Thiol can be used in drug delivery research .
    PLLA1000-PEG5000-Thiol
  • HY-167311
    PLLA1000-PEG3000-Thiol

    		Biochemical Assay Reagents Others
    PLLA1000-PEG3000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA1000-PEG3000-Thiol can be used in drug delivery research .
    PLLA1000-PEG3000-Thiol
  • HY-167312
    PLLA1000-PEG2000-Thiol

    		Biochemical Assay Reagents Others
    PLLA1000-PEG2000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA1000-PEG2000-Thiol can be used in drug delivery research .
    PLLA1000-PEG2000-Thiol
  • HY-167313
    PLLA1000-PEG1000-Thiol

    		Biochemical Assay Reagents Others
    PLLA1000-PEG1000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA1000-PEG1000-Thiol can be used in drug delivery research .
    PLLA1000-PEG1000-Thiol
  • HY-167314
    PLLA10000-PEG5000-Thiol

    		Biochemical Assay Reagents Others
    PLLA10000-PEG5000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA10000-PEG5000-Thiol can be used in drug delivery research .
    PLLA10000-PEG5000-Thiol
  • HY-167315
    PLLA10000-PEG3000-Thiol

    		Biochemical Assay Reagents Others
    PLLA10000-PEG3000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA10000-PEG3000-Thiol can be used in drug delivery research .
    PLLA10000-PEG3000-Thiol
  • HY-167316
    PLLA10000-PEG2000-Thiol

    		Biochemical Assay Reagents Others
    PLLA10000-PEG2000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA10000-PEG2000-Thiol can be used in drug delivery research .
    PLLA10000-PEG2000-Thiol
  • HY-167317
    PLLA10000-PEG1000-Thiol

    		Biochemical Assay Reagents Others
    PLLA10000-PEG1000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA10000-PEG1000-Thiol can be used in drug delivery research .
    PLLA10000-PEG1000-Thiol
  • HY-P10053
    sPLA2-IIA Inhibitor

    		Phospholipase Metabolic Disease
    sPLA2-IIA Inhibitor is a cyclic pentapeptide analog of FLSYK (cyclic 2-Nal-Leu-Ser-2-Nal-Arg (c2)), that binds to hGIIA (human IIA phospholipase A2) and inhibits its hydrolytic ability. sPLA2 is a member of the esterase superfamily that catalyzes the hydrolysis of the ester bond at the sn-2 position of glycerophospholipids, releasing free fatty acids such as arachidonic acid and lysophospholipids .
    sPLA2-IIA Inhibitor
  • HY-P2988A
    α2-3,6 Neuraminidase, Bifidobacterium infantis

    		Others Metabolic Disease
    α2-3,6 Neuraminidase, Bifidobacterium infantis is a highly specific exoglycosidase that catalyzes the hydrolysis of non-reducing terminal α2-3 and α2-6 unbranched sialic acid residues from complex carbohydrates and glycoproteins. α2-3,6 Neuraminidase does not exhibit activity on α2-8 or branched sialic acids .
    α2-3,6 Neuraminidase, Bifidobacterium infantis
  • HY-129934
    Latanoprost ethyl amide

    Lat-NEt

    		 Prostaglandin Receptor Endocrinology
    Latanoprost ethyl amide (Lat-NEt) is a latanoprost analog in which the C-1 carboxyl group has been modified to an N-ethyl amide. Prostaglandin esters have been shown to have ocular hypotensive activity.1 Prostaglandin N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs. Although it has been claimed that prostaglandin ethyl amides are not converted to the free acids in vivo, studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various prostaglandins to the free acids with a conversion rate of about 2.5 μg/g corneal tissue/hr. Lat-NEt would be expected to show the typical intraocular effects of Latanoprost free acid, but with the much slower hydrolysis pharmacokinetics of the prostaglandin N-amides.
    Latanoprost ethyl amide
  • HY-133724
    Vardenafil N-oxide

    		Drug Metabolite Metabolic Disease Inflammation/Immunology Endocrinology
    Vardenafil N-oxide is a N-Oxide impurity of Vardenafil (HY-B0442) .
    Vardenafil N-oxide
  • HY-133724R
    Vardenafil N-oxide (Standard)

    		Drug Metabolite Metabolic Disease Inflammation/Immunology Endocrinology
    Vardenafil N-oxide (Standard) is the analytical standard of Vardenafil N-oxide. This product is intended for research and analytical applications. Vardenafil N-oxide is a N-Oxide impurity of Vardenafil (HY-B0442) .
    Vardenafil N-oxide (Standard)
  • HY-129934S
    Latanoprost ethyl amide-d4

    Lat-NEt-d4

    		 Isotope-Labeled Compounds Prostaglandin Receptor Endocrinology
    Latanoprost ethyl amide-d4 (Lat-NEt-d4) is deuterium labeled Latanoprost ethyl amide. Latanoprost ethyl amide (Lat-NEt) is a latanoprost analog in which the C-1 carboxyl group has been modified to an N-ethyl amide. Prostaglandin esters have been shown to have ocular hypotensive activity.1 Prostaglandin N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs. Although it has been claimed that prostaglandin ethyl amides are not converted to the free acids in vivo, studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various prostaglandins to the free acids with a conversion rate of about 2.5 μg/g corneal tissue/hr. Lat-NEt would be expected to show the typical intraocular effects of Latanoprost free acid, but with the much slower hydrolysis pharmacokinetics of the prostaglandin N-amides .
    Latanoprost ethyl amide-d4
  • HY-121465
    Stearoyl Serotonin

    		Endogenous Metabolite Metabolic Disease
    Stearoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin. Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid-type 1 (TRPV1) channel, reducing both acute and chronic peripheral pain. The effects of replacing the arachidonoyl portion with the saturated 18-carbon stearoyl moiety have not been studied. However, replacement of arachidonate with saturated 11- or 12-carbon fatty acids produces compounds that potently inhibit capsaicin-induced TRPV1 channel activation (IC50=0.76 μM) without blocking FAAH-mediated hydrolysis of arachidonoyl ethanolamine (IC50 > 50 μM).
    Stearoyl Serotonin
  • HY-135115
    Oleuropein Aglycone

    3,4-DHPEA-EA

    		 HDAC Adrenergic Receptor Inflammation/Immunology
    Oleuropein Aglycone (3,4-DHPEA-EA) is a polyphenol and the aglycone form of oleuropein (HY-N0292), formed by enzymatic, acidic or acetylated hydrolysis of oleuropein. Dietary intake of oleuropein Aglycone (50 mg/kg diet) increases the number of neuronal autophagic vesicles, reverses cognitive deficits in the TgCRND8 transgenic mouse model of Alzheimer's disease, and reduces the levels of histone deacetylase 2 (HDAC2) in the cortex and hippocampus. Oleuropein Aglycone increases urinary norepinephrine, interscapular brown adipose tissue epinephrine, and UCP1 protein levels, and reduced plasma leptin levels and total abdominal adipose tissue weight in a rat model of high-fat diet-induced obesity. Oleuropein Aglycone also reduced lung neutrophil infiltration, lipid peroxidation, and IL-1β levels in a mouse model of carrageenan-induced pleurisy.
    Oleuropein Aglycone

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