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adrenergic energy

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100935
    Cimaterol

    CL 263780; (±)-2-Amino-5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]benzonitrile

    		 Adrenergic Receptor Metabolic Disease
    Cimaterol (CL 263780) is a β-adrenergic agonist on energy metabolism in ob/ob mice . The Kd for Cimaterol binding to the L6 β-receptor is 26 nM which is compatible with its EC50 for the stimulation of protein synthesis (approx 5 nM) .
    Cimaterol
  • HY-14607
    Besipirdine hydrochloride

    HP 749

    		 Potassium Channel Neurological Disease
    Besipirdine (hydrochloride) is a potassium channel blocker with cholinergic and adrenergic activity. The cholinergic activity of Besipirdine (hydrochloride) involves stimulating phosphatidylinositol turnover and reducing potassium currents. The adrenergic activity of Besipirdine (hydrochloride) involves stimulating norepinephrine release, which is attributed to the inhibition of presynaptic α2-adrenergic receptors and the inhibition of norepinephrine uptake. Besipirdine (hydrochloride) may be used in research for Alzheimer's disease .
    Besipirdine hydrochloride

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