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Results for "

aggrecanase 2

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

2

Peptides

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-114996
    ADAMTS-5 Inhibitor
    3 Publications Verification

    		 ADAMTS Inflammation/Immunology
    ADAMTS-5 Inhibitor is a potent ADAMTS-5 (aggrecanase-2) inhibitor, with an IC50 of 1.1 µM. ADAMTS-5 Inhibitor shows >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1) .
    ADAMTS-5 Inhibitor
  • HY-P5419A
    WAAG-3R TFA

    		Biochemical Assay Reagents Others
    WAAG-3R TFA is a biological active peptide. (Aggrecanases belong to the ADAMTS (A disintegrin and metalloprotease with thrombospondin motif) family of proteases. Aggrecanases cleave aggrecan, the major structural component of cartilage. Aggrecanase-1 (ADAMTS-4) is a major aggrecanase in human osteoarthritic cartilage. This FRET peptide was used in an ADAMTS-4 (Aggrecanase-1) and ADAMTS-5 (Aggrecanase-2) assay . (Ex/Em = 340/420 nm)
    WAAG-3R TFA
  • HY-160822
    AGG-523

    PF-5212371

    		 ADAMTS Inflammation/Immunology
    AGG-523 (PF-5212371) is a reversible, non-hydroxamate, zinc-binding selective aggrecanase 1 (ADAMTS4) and aggrecanase 2 (ADAMTS5) inhibitor. AGG-523 can be used for the study of osteoarthritis (OA) .
    AGG-523

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