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Results for "

autoxidation

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

1

Fluorescent Dye

2

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1459
    BODIPY 665/676

    		Fluorescent Dye Metabolic Disease
    BODIPY 665/676 is a lipophilic radical-sensitive fluorescent probe that can be used to study radical-driven lipid autoxidation (Ex/Em=665/676 nm) .
    BODIPY 665/676
  • HY-116663
    (±)20-HDHA

    (±)20-HDoHE

    		 Endogenous Metabolite Neurological Disease
    (±)20-HDHA ((±)20-HDoHE) is a racemic mixture and is an autoxidation product of Docosahexaenoic acid (DHA). (±)20-HDHA is also formed by peroxidation process in human platelets and rat brain homogenate .
    (±)20-HDHA
  • HY-119977
    APF

    		Reactive Oxygen Species (ROS) Others
    APF is a fluorescence probe that can selectively, and dose dependently detect certain species among ROS and that are highly resistant to autoxidation. APF can be used in enzymatic and cellular systems .
    APF
  • HY-N3102
    p-Coumaryl alcohol

    p-Hydroxycinnamyl alcohol

    		 Others Others
    p-Coumaryl alcohol is an antioxidant that can be isolated from Alpinia officinarum Hance. p-Coumaryl alcohol has inhibitory effect during the autoxidation of methyl linoleate .
    p-Coumaryl alcohol
  • HY-112678
    TM6008

    		HIF/HIF Prolyl-Hydroxylase Cardiovascular Disease
    TM6008 is a potent and orally active prolyl hydroxylase (PHD) inhibitor. TM6008 chelats transition metal (copper) and inhibits the autoxidation of ascorbic acid with an IC50 value is 0.57 μM. TM6008  exerts organ protection against ischemia in vivo and can be used for cerebrovascular disease research .
    TM6008
  • HY-W140598S
    Triphenylsulfonium-d5 chloride

    		Isotope-Labeled Compounds Others
    Triphenylsulfonium-d5 chloride is deuterium labeled Triphenylsulfonium chloride. Triphenylsulfonium chloride is an autoxidation catalyst .
    Triphenylsulfonium-d5 chloride
  • HY-138241
    PBD-BODIPY

    		Fluorescent Dye Others
    PBD-BODIPY is a probe for the spectrophotometric measurement of autoxidation reactions. Co-autoxidation of the PBD-BODIPY signal carrier and a hydrocarbon co-substrate can be quantified by monitoring loss of absorbance at 591 nm. PBD-BODIPY has been used to measure the activity of radical-trapping antioxidants in cell-free assays. It has also been used as a fluorescent probe for the detection of epoxidation activity.
    PBD-BODIPY
  • HY-130289
    (±)4-HDHA

    4-Hydroxy docosahexaenoic acid; (±)4-HDoHE

    		 PPAR Metabolic Disease Inflammation/Immunology
    (±)4-HDHA (4-Hydroxy docosahexaenoic acid) is an autoxidation product of Docosahexaenoic acid (HY-B2167) (DHA). (±)4-HDHA is a PPARγ agonist, antidiabetic and anti-inflammatory agent .
    (±)4-HDHA
  • HY-130238
    (±)8-HDHA

    (±)8-HDoHE; 8-hydroxy Docosahexaenoic acid; (±)8-HDoHE

    		 Endogenous Metabolite Metabolic Disease
    (±)8-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±)8-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
    (±)8-HDHA
  • HY-130287
    (±)16-HDHA

    (±)16-HDoHE; 16-hydroxy Docosahexaenoic acid; (±)16-HDoHE

    		 Endogenous Metabolite Metabolic Disease
    (±)16-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±)16-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
    (±)16-HDHA
  • HY-130288
    (±)13-HDHA

    (±)13-HDoHE; 13-hydroxy Docosahexaenoic acid; (±)13-HDoHE

    		 Lipoxygenase Inflammation/Immunology
    (±)13-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. Fresh water hydra is shown to metabolize DHA to 13(R)-HDHA, presumably via the 11R-lipoxygenase activity. (±)13-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
    (±)13-HDHA
  • HY-W587878
    Thujopsene

    		Cytochrome P450 Pyruvate Kinase Fungal Apoptosis Insecticide Infection Cancer
    Thujopsene is the inhibitor for cytochrome P450, that inhibits CYP2B6, CYP3A4, CYP2C19, CYP2C8, CYP2C9 with IC50s of 1.3, 12.6, 13.6, 29.8, and 44.9 μM, respectively. Thujopsene binds to PKM2, inhibits the metabolism pathway of cancer cell, induces apoptosis in MKN45, thereby exhibiting antitumor efficacy. Thujopsene exhibits anti-termite and antifungal activities through autoxidation .
    Thujopsene

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