2. Search Result
Search Result
Results for "

docosahexaenoic

" in MedChemExpress (MCE) Product Catalog:

51

Inhibitors & Agonists

3

Biochemical Assay Reagents

8

Natural
Products

10

Isotope-Labeled Compounds

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-107343
    Docosahexaenoic acid ethyl ester

    Ethyl docosahexaenoate

    		 Others Neurological Disease Metabolic Disease
    Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) is a 90% concentrated ethyl ester of docosahexaenoic acid manufactured from the microalgal oil. Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum. Docosahexaenoic acid (DHA) is a key component of the cell membrane, and its peroxidation is inducible due to the double-bond chemical structure. Docosahexaenoic acid has neuroprotective effects .
    Docosahexaenoic acid ethyl ester
  • HY-101541
    Docosahexaenoic acid methyl ester

    Methyl docosahexaenoate; all cis-DHA methyl ester

    		 Others Neurological Disease
    Docosahexaenoic Acid methyl ester is a methylated docosahexaenoic acid analog which can be intercalated into membrane phospholipids without being oxidized or hydrolyzed.
    Docosahexaenoic acid methyl ester
  • HY-B2167
    Docosahexaenoic acid
    Maximum Cited Publications
    26 Publications Verification

    DHA; Cervonic acid

    		 Endogenous Metabolite Neurological Disease Cancer
    Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
    Docosahexaenoic acid
  • HY-B2167S
    Docosahexaenoic acid-d5

    DHA-d5; Cervonic acid-d5

    		 Endogenous Metabolite Neurological Disease
    Docosahexaenoic acid-d5 is the deuterium labeled Docosahexaenoic Acid. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
    Docosahexaenoic acid-d5
  • HY-107343R
    Docosahexaenoic acid ethyl ester (Standard)

    		Others Neurological Disease Metabolic Disease
    Docosahexaenoic acid ethyl ester (Standard) is the analytical standard of Docosahexaenoic acid ethyl ester. This product is intended for research and analytical applications. Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) is a 90% concentrated ethyl ester of docosahexaenoic acid manufactured from the microalgal oil. Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum. Docosahexaenoic acid (DHA) is a key component of the cell membrane, and its peroxidation is inducible due to the double-bond chemical structure. Docosahexaenoic acid has neuroprotective effects .
    Docosahexaenoic acid ethyl ester (Standard)
  • HY-101541R
    Docosahexaenoic acid methyl ester (Standard)

    		Others Neurological Disease
    Docosahexaenoic acid methyl ester (Standard) is the analytical standard of Docosahexaenoic acid methyl ester. This product is intended for research and analytical applications. Docosahexaenoic Acid methyl ester is a methylated docosahexaenoic acid analog which can be intercalated into membrane phospholipids without being oxidized or hydrolyzed.
    Docosahexaenoic acid methyl ester (Standard)
  • HY-B2167R
    Docosahexaenoic acid (Standard)

    		Endogenous Metabolite Neurological Disease Cancer
    Docosahexaenoic acid (Standard) is the analytical standard of Docosahexaenoic acid. This product is intended for research and analytical applications. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk. In Vitro: Docosahexaenoic acid (DHA) is essential for the growth and functional development of the brain in infants. DHA is also required for maintenance of normal brain function in adults. The inclusion of plentiful DHA in the diet improves learning ability and memory . DHA is an essential requirement in every step of brain development like neural cell proliferation, migration, differentiation, synaptogenesis. The multiple double bonds and unique structure allow DHA to impart special membrane characteristics for effective cell signaling. Many development disorders like dyslexia, autism spectrum disorder, attention deficit hyperactivity disorder, schizophrenia etc. are causally related to decreased level of DHA . DHA is a potent RXR ligand inducing robust RXR activation already at low micro molar concentrations. The EC50 for RXRα activation by DHA is about 5-10 μM fatty acid . In Vivo: Docosahexaenoic acid administration over 10 weeks significantly reduces the number of reference memory errors, without affecting the number of working memory errors, and significantly increases the docosahexaenoic acid content and the docosahexaenoic acid/arachidonic acid ratio in both the hippocampus and the cerebral cortex . DHA treatment exerts neuroprotective actions on an experimental mouse model of PD. There is a decrease tendency in brain lipid oxidation of MPTP mice but it does not significantly .
    Docosahexaenoic acid (Standard)
  • HY-107343S
    Docosahexaenoic acid ethyl ester-d5

    Ethyl docosahexaenoate-d5

    		 Isotope-Labeled Compounds Neurological Disease Metabolic Disease
    Docosahexaenoic acid ethyl ester-d5 is the deuterium labeled Docosahexaenoic acid ethyl ester. Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) is a 90% concentrated ethyl ester of docosahexaenoic acid manufactured from the microalgal oil. Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum. Docosahexaenoic acid (DHA) is a key component of the cell membrane, and its peroxidation is inducible due to the double-bond chemical structure. Docosahexaenoic acid has neuroprotective effects[1][2].
    Docosahexaenoic acid ethyl ester-d5
  • HY-107343S1
    Docosahexaenoic acid ethyl ester-d5-1

    Ethyl docosahexaenoate-d5-1

    		 Isotope-Labeled Compounds Others
    Docosahexaenoic acid ethyl ester-d5-1 is the deuterium labeled Docosahexaenoic acid ethyl ester. Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) is a 90% concentrated ethyl ester of docosahexaenoic acid manufactured from the microalgal oil. Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum. Docosahexaenoic acid (DHA) is a key component of the cell membrane, and its peroxidation is inducible due to the double-bond chemical structure. Docosahexaenoic acid has neuroprotective effects[1][2][3].
    Docosahexaenoic acid ethyl ester-d5-1
  • HY-101541S
    Docosahexaenoic acid-d5 methyl ester

    Methyl docosahexaenoate-d5; all cis-DHA methyl ester-d5

    		 Isotope-Labeled Compounds Neurological Disease
    Docosahexaenoic acid-d5 methyl ester is the deuterium labeled Docosahexaenoic Acid methyl ester. Docosahexaenoic Acid methyl ester is a methylated docosahexaenoic acid analog which can be intercalated into membrane phospholipids without being oxidized or hydrolyzed[1][2].
    Docosahexaenoic acid-d5 methyl ester
  • HY-101541S1
    Docosahexaenoic acid-13C22 methyl ester

    Methyl docosahexaenoate-13C22; all cis-DHA methyl ester-13C22

    		 Isotope-Labeled Compounds Others
    Docosahexaenoic acid- 13C22 methyl ester is the 13C22 labeled Docosahexaenoic acid methyl ester (HY-101541)[1].
    Docosahexaenoic acid-13C22 methyl ester
  • HY-130289
    (±)4-HDHA

    4-Hydroxy docosahexaenoic acid; (±)4-HDoHE

    		 PPAR Metabolic Disease Inflammation/Immunology
    (±)4-HDHA (4-Hydroxy docosahexaenoic acid) is an autoxidation product of Docosahexaenoic acid (HY-B2167) (DHA). (±)4-HDHA is a PPARγ agonist, antidiabetic and anti-inflammatory agent .
    (±)4-HDHA
  • HY-124019
    4,5-DiHDPA lactone

    		PPAR Neurological Disease
    4,5-DiHDPA lactone (5), a derivative of docosahexaenoic acid (DHA), is a PPARγ activator .
    4,5-DiHDPA lactone
  • HY-130239A
    (±)14-HDHA

    (±)14-HDoHE; 14-hydroxy docosahexaenoic acid; (±)14-HDoHE

    		 Drug Metabolite Neurological Disease
    (±)14-HDHA is the isomer of 14(S)-HDHA (HY-130239). 14(S)-HDHA is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway .
    (±)14-HDHA
  • HY-130550
    (±)7(8)-EpDPA

    		Endogenous Metabolite Others
    (±)7(8)-EpDPA is an epoxide derivative of docosahexaenoic acid (DHA) metabolized by CYP450 .
    (±)7(8)-EpDPA
  • HY-157690
    19(S),20(R)-EDP

    		Others Others
    19(S),20(R)-EDP is an epoxidized metabolite of docosahexaenoic acid (HY-B2167) .
    19(S),20(R)-EDP
  • HY-134997
    4-Oxo Docosahexaenoic Acid

    4-oxo DHA

    		 Others Cancer
    4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of Docosahexaenoic acid (HY-B2167) with antiproliferative and PPARγ agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 μM, however it increased proliferation of MCF-7 cells. 4-oxo DHA binds covalently to PPARγ and activates gene transcription in luciferase reporter assays and in dendritic cells with EC50 values of approximately 8-16 μM.
    4-Oxo Docosahexaenoic Acid
  • HY-120178
    (±)7(8)-DiHDPA

    		Others Cardiovascular Disease
    (±)7(8)-DiHDPA is a epoxygenase metabolite of docosahexaenoic acid (HY-B2167). (±)7(8)-DiHDPA inhibits platelet aggregation at concentrations below those affecting thromboxane synthesis .
    (±)7(8)-DiHDPA
  • HY-120442
    (±)16(17)-DiHDPA

    		Others Cardiovascular Disease
    (±)16(17)-DiHDPA is a epoxygenase metabolite of docosahexaenoic acid (HY-B2167). (±)16(17)-DiHDPA inhibits platelet aggregation at concentrations below those affecting thromboxane synthesis .
    (±)16(17)-DiHDPA
  • HY-130238
    (±)8-HDHA

    (±)8-HDoHE; 8-hydroxy docosahexaenoic acid; (±)8-HDoHE

    		 Endogenous Metabolite Metabolic Disease
    (±)8-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±)8-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
    (±)8-HDHA
  • HY-130287
    (±)16-HDHA

    (±)16-HDoHE; 16-hydroxy docosahexaenoic acid; (±)16-HDoHE

    		 Endogenous Metabolite Metabolic Disease
    (±)16-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±)16-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
    (±)16-HDHA
  • HY-157690A
    19(R),20(S)-EDP

    		Others Others
    19(R),20(S)-EDP (compound 19(S),20(R)-2a) is an oxylipin and a metabolite of docosahexaenoic acid (HY-B2167) .
    19(R),20(S)-EDP
  • HY-130419
    (±)13(14)-EpDPA

    13,14-EpDPE

    		 Others Cardiovascular Disease Neurological Disease
    (±)13(14)-EpDPA (13,14-EpDPE) is the product of the reaction of cytochrome P-450 epoxygenase with Docosahexaenoic Acid (DHA).(±)13(14)-EpDPA has antihyperalgesic and vasorelaxative activities .
    (±)13(14)-EpDPA
  • HY-136540
    Resolvin D3

    RvD3

    		 Others Inflammation/Immunology
    Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation .
    Resolvin D3
  • HY-19886
    F 16915

    		Others Cardiovascular Disease
    F 16915, a Docosahexaenoic Acid (DHA, HY-B2167) derivative, is a potent pro-agent of DHA. F 16915 can prevent heart failure-induced atrial fibrillation .
    F 16915
  • HY-167579
    4-trans,7-cis,10-cis,13-cis,16-cis,19-cis-Docosahexaenoic acid

    		Biochemical Assay Reagents
    4-trans,7-cis,10-cis,13-cis,16-cis,19-cis-Docosahexaenoic acid is a kind of biochemical reagent.
    4-trans,7-cis,10-cis,13-cis,16-cis,19-cis-Docosahexaenoic acid
  • HY-113777
    22-HDHA

    22-Hydroxy docosahexaenoic acid; 22-OH DHA

    		 Others Metabolic Disease
    22-HDHA is an oxidation product of docosahexaenoic acid.1 In vitro, it is formed upon incubation of rat liver microsomes with DHA and NADPH and also by the human cytochrome P450 (CYP) isoform CYP4F3B in BTI-TN-5B1-4 microsomes. Serum levels of 22-HDHA increase following dietary DHA supplementation in humans.
    22-HDHA
  • HY-130288
    (±)13-HDHA

    (±)13-HDoHE; 13-hydroxy docosahexaenoic acid; (±)13-HDoHE

    		 Others Inflammation/Immunology
    (±)13-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. Fresh water hydra is shown to metabolize DHA to 13(R)-HDHA, presumably via the 11R-lipoxygenase activity. (±)13-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
    (±)13-HDHA
  • HY-130286
    10-Hydroxy-4(Z),7(Z),11(E),13(Z),16(Z),19(Z)-docosahexaenoic acid

    		Others Metabolic Disease
    10-Hydroxy-4(Z),7(Z),11(E),13(Z),16(Z),19(Z)-docosahexaenoic acid is an ester product.
    10-Hydroxy-4(Z),7(Z),11(E),13(Z),16(Z),19(Z)-docosahexaenoic acid
  • HY-130413
    Protectin D1

    Neuroprotectin D1; NPD1

    		 Endogenous Metabolite Neurological Disease
    Protectin D1, neuroprotectin D1 when generated by neural cells, is a member of a new family of bioactive products generated from docosahexaenoic acid. Protectin D1 is also a specialized pro-resolving mediator with potent pro-resolving and anti-inflammatory effects in vivo in several human disease models .
    Protectin D1
  • HY-139408
    17-Oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-docosahexaenoic acid

    17-Oxo-DHA; 17-Oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-DHA

    		 PPAR Keap1-Nrf2 Metabolic Disease
    17-Oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-docosahexaenoic acid (17-Oxo-DHA) is a metabolite of lipoxygenase-mediated oxidation of DHA. 17-Oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-docosahexaenoic acid is a PPARγ agonist and activates a Nrf2 dependent antioxidant reaction .
    17-Oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-docosahexaenoic acid
  • HY-130239
    14(S)-HDHA

    14(S)-HDoHE

    		 Drug Metabolite Neurological Disease
    14(S)-HDHA (14(S)-HDoHE) is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway .
    14(S)-HDHA
  • HY-120312
    PCTR3

    		Others Others
    PCTR3 is a Docosahexaenoic acid DHA (HY-B2167) derivative, which acts as a pro-resolving and tissue regeneration lipid mediator .
    PCTR3
  • HY-158623
    (±)13(14)-DiHDPA

    (±)13,14-DiHDPE

    		 Drug Metabolite Inflammation/Immunology
    (±)13(14)-DiHDPA ((±)13,14-DiHDPE) a metabolite of Docosahexaenoic acid (DHA; HY-B2167) by P450 (CYP) metabolic pathways .
    (±)13(14)-DiHDPA
  • HY-126041A
    (±)10(11)-EpDPA

    (±)10,11-EDP; (±)10,11-EpDPE; (±)10,11-Epoxy docosapentaenoic acid

    		 Epoxide Hydrolase Metabolic Disease
    (±)10(11)-EpDPA, a docosahexaenoic acid epoxygenase metabolite, acts as a substrate for soluble epoxide hydrolase (sEH) with a Km value of 5.1 µM for human sEH .
    (±)10(11)-EpDPA
  • HY-119684
    Maresin 2

    		Others Inflammation/Immunology
    Maresin 2 is an anti-inflammatory and pro-resolving mediator from human macrophages. Maresins are a new family of anti-inflammatory and pro-resolving lipid mediators biosynthesized from docosahexaenoic acid (DHA) by macrophages .
    Maresin 2
  • HY-116663
    (±)20-HDHA

    (±)20-HDoHE

    		 Endogenous Metabolite Neurological Disease
    (±)20-HDHA ((±)20-HDoHE) is a racemic mixture and is an autoxidation product of Docosahexaenoic acid (DHA). (±)20-HDHA is also formed by peroxidation process in human platelets and rat brain homogenate .
    (±)20-HDHA
  • HY-116429
    Maresin 1
    2 Publications Verification

    		 Reactive Oxygen Species Inflammation/Immunology
    Maresin 1, produced by human Mφs from endogenous docosahexaenoic acid (DHA) and a specialized proresolving mediator, stimulates intracellular [Ca 2+] and secretion. Maresin 1 possesses anti-inflammatory activity .
    Maresin 1
  • HY-136540S
    Resolvin D3-d5

    RvD3-d5

    		 Isotope-Labeled Compounds Inflammation/Immunology
    Resolvin D3-d5 is the deuterium labeled Resolvin D3. Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation[1][2].
    Resolvin D3-d5
  • HY-120255A
    17(S)-HDHA

    		PPAR Metabolic Disease
    17(S)-HDHA is a pro-resolving mediator (SPM). 17(S)-HDHA slightly activats PPARγ, PPARα and PPARδ .
    17(S)-HDHA
  • HY-116429S
    Maresin 1-d5

    		Isotope-Labeled Compounds Reactive Oxygen Species Inflammation/Immunology
    Maresin 1-d5 is the deuterium labeled Maresin 1. Maresin 1, produced by human Mφs from endogenous docosahexaenoic acid (DHA) and a specialized proresolving mediator, stimulates intracellular [Ca2+] and secretion. Maresin 1 possesses anti-inflammatory activity[1][2][3].
    Maresin 1-d5
  • HY-142974
    1,2-Dioleoyl-3-Docosohexaenoyl-rac-glycerol

    1,2-Olein-3-Docosohexaenoin; 18:1/18:1/22:6-TG; C1OO

    		 Endogenous Metabolite Metabolic Disease
    1,2-Dioleoyl-3-docosohexaenoyl-rac-glycerol is a triacylglycerol that contains oleic acid (HY-N1446) at the sn-1 and sn-2 positions and docosahexaenoic acid (HY-B2167) at the sn-3 position. It has been detected in human breast milk.
    1,2-Dioleoyl-3-Docosohexaenoyl-rac-glycerol
  • HY-121636
    Resolvin D2
    4 Publications Verification

    RvD2

    		 TRP Channel Infection Neurological Disease Inflammation/Immunology
    Resolvin D2 is a metabolite of docosahexaenoic acid (DHA), with anti-inflammatory, anti-infective activities. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Resolvin D2 is a remarkably potent inhibitor of TRPV1 (IC50 = 0.1 nM) and TRPA1 (IC50 = 2 nM) in primary sensory neurons .
    Resolvin D2
  • HY-125527
    Resolvin D1

    RvD1

    		 Endogenous Metabolite Inflammation/Immunology
    Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α–mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages .
    Resolvin D1
  • HY-116124
    17(S)-HpDHA

    		Lipoxygenase Others
    17(S)-HpDHA is the main 15-Lipoxygenase (LOX) isoenzyme: h15-LOX-1 and h15-LOX-2 and docosahexaenoic acid (DHA). product. 17(S)-HpDHA negatively regulates epoxide synthesis via allosteric regulation. 17(S)-HpDHA also inhibits platelet aggregation with an EC50 of approximately 1 μM .
    17(S)-HpDHA
  • HY-121636S
    Resolvin D2-d5

    RvD2-d5

    		 TRP Channel Infection Neurological Disease Inflammation/Immunology
    Resolvin D2-d5 is the deuterium labeled Resolvin D2. Resolvin D2 is a metabolite of docosahexaenoic acid (DHA), with anti-inflammatory, anti-infective activities. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Resolvin D2 is a remarkably potent inhibitor of TRPV1 (IC50 = 0.1 nM) and TRPA1 (IC50 = 2 nM) in primary sensory neurons[1][2][3].
    Resolvin D2-d5
  • HY-120255AS
    17(S)-HDHA-d5

    17(S)-Hydroxy docosahexaenoic acid-d5, 17(S)-HDoHE-d5

    		 Isotope-Labeled Compounds Others
    17(S)-HDHA-d5 is the deuterium labeled 17(S)-HDHA[1].
    17(S)-HDHA-d5
  • HY-125527S
    Resolvin D1-d5

    RvD1-d5

    		 Isotope-Labeled Compounds Endogenous Metabolite Inflammation/Immunology
    Resolvin D1-d5 is the deuterium labeled Resolvin D1. Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α–mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages[1][2].
    Resolvin D1-d5
  • HY-120978
    Omega-3 arachidonic acid methyl ester

    ω-3 Arachidonic acid methyl ester; (all-Z)-8,11,14,17-Eicosatetraenoic acid methyl ester

    		 Biochemical Assay Reagents Others
    omega-3 Arachidonic Acid methyl ester, mainly docosahexaenoic acid, eicosapentaenoic acid and α-Linoleic acid, represented by linoleic acid, is an essential dietary nutrient required for normal growth and development.Omega-3Methyl arachidonic acid is a rare fatty acid Omega-3Neutral fat-soluble form of arachidonic acid. Omega-3Fatty acids, as a group, were associated with reduced inflammation and autoimmune activity, as well as reduced thrombosis and platelet activation.
    Omega-3 arachidonic acid methyl ester
  • HY-N7833
    Heneicosapentaenoic acid

    		Biochemical Assay Reagents Others
    Heneicosapentaenoic Acid (HPA) is a 21:5 omega-3 fatty acid found in trace amounts in the green alga B. pennata and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA), except that a carbon is extended at the carboxy terminus, placing the first double bond at the δ6 position. HPA can be used to study the importance of double bond position in omega-3 fatty acids. It incorporates phospholipids and triacylglycerols in vivo with the same efficiency as EPA and docosahexaenoic acid, and exhibits a strong inhibitory effect on the synthesis of arachidonic acid from linoleic acid. HPA is a poor substrate for prostaglandin H synthase (PGHS) (cyclooxygenase) and 5-lipoxygenase, but retains the ability to rapidly inactivate PGHS.
    Heneicosapentaenoic acid

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: