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ibuprofen

" in MedChemExpress (MCE) Product Catalog:

45

Inhibitors & Agonists

1

Screening Libraries

3

Natural
Products

10

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-78131
    Ibuprofen
    Maximum Cited Publications
    15 Publications Verification

    (±)-ibuprofen

    		 COX Apoptosis Parasite Infection Neurological Disease Inflammation/Immunology Cancer
    Ibuprofen ((±)-Ibuprofen) is a potent, orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen ((±)-Ibuprofen) can be used in the research of pain, swelling, inflammation, infection, immunology, cancers .
    Ibuprofen
  • HY-78131C
    Ibuprofen sodium
    Maximum Cited Publications
    15 Publications Verification

    (±)-ibuprofen sodium

    		 COX Apoptosis Parasite Infection Neurological Disease Inflammation/Immunology Cancer
    Ibuprofen ((±)-Ibuprofen) sodium is an orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen sodium inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen sodium is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen sodium can be used in the research of pain, swelling, inflammation, infection, immunology, cancers .
    Ibuprofen sodium
  • HY-100586
    Ibuprofen L-lysine
    Maximum Cited Publications
    15 Publications Verification

    (±)-ibuprofen L-lysine

    		 COX Apoptosis Parasite Infection Inflammation/Immunology Cancer
    Ibuprofen ((±)-Ibuprofen) L-lysine is a potent orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen L-lysine inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen L-lysine is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen L-lysine can be used in the research of pain, swelling, inflammation, infection, immunology, cancers .
    Ibuprofen L-lysine
  • HY-78131CS
    Ibuprofen-d3 sodium

    (±)-ibuprofen-d3 sodium

    		 Apoptosis COX Isotope-Labeled Compounds Others
    Ibuprofen-d3 (sodium) is the deuterium labeled Ibuprofen sodium[1].
    Ibuprofen-d3 sodium
  • HY-78131S
    Ibuprofen-d3

    (±)-ibuprofen-d3

    		 COX Inflammation/Immunology
    Ibuprofen-d3 is a deuterium labeled Ibuprofen. Ibuprofen is a COX-1 and COX-2 inhibitor with IC50s of 13 μM and 370 μM[1].
    Ibuprofen-d3
  • HY-78131R
    Ibuprofen (Standard)

    		COX Apoptosis Parasite Infection Neurological Disease Inflammation/Immunology Cancer
    Ibuprofen (Standard) is the analytical standard of Ibuprofen. This product is intended for research and analytical applications. Ibuprofen ((±)-Ibuprofen) is a potent, orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen ((±)-Ibuprofen) can be used in the research of pain, swelling, inflammation, infection, immunology, cancers .
    Ibuprofen (Standard)
  • HY-121899
    1-Oxo Ibuprofen

    ibuprofen EP impurity J

    		 Drug Metabolite Others
    1-Oxo Ibuprofen (Ibuprofen EP impurity J) is a degradation product and a potential impurity in preparations of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively .
    1-Oxo Ibuprofen
  • HY-131314
    Ibuprofen carboxylic acid

    		Drug Metabolite Others
    Ibuprofen carboxylic acid is the metabolite of Ibuprofen (HY-78131), that has high concentrations in wastewater and water environments, and disappears fast during biodegradation, compared to the other ibuprofen metabolite .
    Ibuprofen carboxylic acid
  • HY-113018
    Ibuprofen acyl-β-D-glucuronide

    ibuprofen glucuronide

    		 Endogenous Metabolite TRP Channel Inflammation/Immunology
    Ibuprofen acyl-β-D-glucuronide (Ibuprofen glucuronide) is a selective TRPA1 antagonis. Ibuprofen acyl-β-D-glucuronide reduces AITC-evoked calcium response with an IC50 value of 60μM .
    Ibuprofen acyl-β-D-glucuronide
  • HY-78131S3
    Ibuprofen-13C6

    (±)-ibuprofen-13C6

    		 Isotope-Labeled Compounds Apoptosis Parasite COX Cancer
    Ibuprofen- 13C6 ((±)-Ibuprofen- 13C6) is a 13C labeled Ibuprofen (HY-78131). Ibuprofen ((±)-Ibuprofen) is a potent, orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen ((±)-Ibuprofen) can be used in the research of pain, swelling, inflammation, infection, immunology, cancers .
    Ibuprofen-13C6
  • HY-78131S2
    Ibuprofen-d4

    		Apoptosis COX Parasite Cancer
    Ibuprofen-d4 is a potent, orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen ((±)-Ibuprofen) can be used in the research of pain, swelling, inflammation, infection, immunology, cancers[2][3][4][5].
    Ibuprofen-d4
  • HY-131259
    Ibuprofen Impurity F

    		COX Inflammation/Immunology
    Ibuprofen Impurity F is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively .
    Ibuprofen Impurity F
  • HY-131260
    Ibuprofen Impurity K

    		COX Inflammation/Immunology
    Ibuprofen Impurity K is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively .
    Ibuprofen Impurity K
  • HY-131259R
    Ibuprofen Impurity F (Standard)

    		COX Inflammation/Immunology
    Ibuprofen Impurity F (Standard) is the analytical standard of Ibuprofen Impurity F. This product is intended for research and analytical applications. Ibuprofen Impurity F is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively .
    Ibuprofen Impurity F (Standard)
  • HY-131260R
    Ibuprofen Impurity K (Standard)

    		COX Inflammation/Immunology
    Ibuprofen Impurity K (Standard) is the analytical standard of Ibuprofen Impurity K. This product is intended for research and analytical applications. Ibuprofen Impurity K is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively .
    Ibuprofen Impurity K (Standard)
  • HY-131261R
    Ibuprofen alcohol (Standard)

    		Others Inflammation/Immunology
    Ibuprofen alcohol (Standard) is the analytical standard of Ibuprofen alcohol. This product is intended for research and analytical applications. Ibuprofen alcohol, a nonsteroidal antiinflammatory agent (NSAID), exhibits very little activity for acid-sensing ion channels (ASICs) .
    Ibuprofen alcohol (Standard)
  • HY-131258
    Ibuprofen impurity 1

    		COX Inflammation/Immunology
    Ibuprofen impurity 1 is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively .
    Ibuprofen impurity 1
  • HY-118782
    Ibuprofen diethylaminoethyl ester

    		Others Inflammation/Immunology
    Ibuprofen diethylaminoethyl ester is an acidic antiinflammatory drug with anesthetic effect .
    Ibuprofen diethylaminoethyl ester
  • HY-131314S
    Ibuprofen carboxylic acid-d3

    		Isotope-Labeled Compounds Others
    Ibuprofen carboxylic acid-d3 is the deuterium labeled Ibuprofen carboxylic acid[1].
    Ibuprofen carboxylic acid-d3
  • HY-113018S
    Ibuprofen acyl-β-D-glucuronide-d3

    ibuprofen glucuronide-d3

    		 Isotope-Labeled Compounds Others
    Ibuprofen acyl-β-D-glucuronide-d3 is the deuterium labeled Ibuprofen acyl-β-D-glucuronide[1].
    Ibuprofen acyl-β-D-glucuronide-d3
  • HY-78131S1
    Ibuprofen-13C,d3

    (±)-ibuprofen-13C,d3

    		 Isotope-Labeled Compounds COX Inflammation/Immunology Cancer
    Ibuprofen- 13C,d3 is the 13C- and deuterium labeled Ibuprofen. Ibuprofen is an anti-inflammatory agent targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.
    Ibuprofen-13C,d3
  • HY-131261
    Ibuprofen alcohol

    		Others Inflammation/Immunology
    Ibuprofen alcohol, a nonsteroidal antiinflammatory agent (NSAID), exhibits very little activity for acid-sensing ion channels (ASICs) .
    Ibuprofen alcohol
  • HY-108308
    Ibuprofen guaiacol ester

    Methoxybutropate; AF 2259; Metoxibutropate

    		 Prostaglandin Receptor Metabolic Disease Inflammation/Immunology
    Ibuprofen guaiacol ester (AF 2259; Metoxibutropate) is a potent and orally active prostaglandin synthesis inhibitor. Ibuprofen guaiacol ester has the potential for the research of edema and fever .
    Ibuprofen guaiacol ester
  • HY-101482
    Ibuprofen piconol

    U75630

    		 Others Inflammation/Immunology
    Ibuprofen piconol is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.
    Ibuprofen piconol
  • HY-111950
    (-)-Ibuprofenamide

    (R)-ibuprofenamide

    		 COX Inflammation/Immunology
    (-)-Ibuprofenamide is an amide proagent of Ibuprofen with anti-inflammatory activity . Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively .
    (-)-Ibuprofenamide
  • HY-113018A
    (S)-Ibuprofen acyl-β-D-glucuronide

    (S)-ibuprofen glucuronide

    		 Drug Metabolite Inflammation/Immunology
    (S)-Ibuprofen acyl-β-D-glucuronide ((S)-Ibuprofen glucuronide) is a compound used to study the metabolism and pharmacokinetics of S-ibuprofen, a non-steroidal anti-inflammatory drug. (S)-Ibuprofen acyl-β-D-glucuronide is an acylglucuronic acid metabolite produced by S-ibuprofen in the liver .
    (S)-Ibuprofen acyl-β-D-glucuronide
  • HY-78131B
    (R)-(-)-Ibuprofen
    2 Publications Verification

    (R)-ibuprofen

    		 NF-κB Inflammation/Immunology Cancer
    (R)-(-)-Ibuprofen is the R enantiomer of Ibuprofen, inactive on COX, inhibits NF-κB activation; (R)-(-)-Ibuprofen exhibits anti-inflammatory and antinociceptive effects.
    (R)-(-)-Ibuprofen
  • HY-126121
    2-Hydroxy Ibuprofen

    (±)-2-Hydroxy ibuprofen

    		 COX Inflammation/Immunology Cancer
    2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.
    2-Hydroxy Ibuprofen
  • HY-78131BS
    (R)-(-)-Ibuprofen-d3

    (R)-ibuprofen-d3

    		 NF-κB Inflammation/Immunology Cancer
    (R)-(-)-Ibuprofen-d3 is the deuterium labeled (R)-(-)-Ibuprofen. (R)-(-)-Ibuprofen is the R enantiomer of Ibuprofen, inactive on COX, inhibits NF-κB activation; (R)-(-)-Ibuprofen exhibits anti-inflammatory and antinociceptive effects.
    (R)-(-)-Ibuprofen-d3
  • HY-78131AR
    (S)-(+)-Ibuprofen (Standard)

    		COX Inflammation/Immunology
    (S)-(+)-Ibuprofen (Standard) is the analytical standard of (S)-(+)-Ibuprofen. This product is intended for research and analytical applications. (S)-(+)-Ibuprofen ((S)-Ibuprofen), a S(+)-enantiomer of Ibuprofen, is a potent COX-1 and COX-2 inhibitor with IC50s of 2.1 μM and 1.6 μM, respectively. (S)-(+)-Ibuprofen has analgesic, anti-inflammatory, anticancer and antipyretic effects .
    (S)-(+)-Ibuprofen (Standard)
  • HY-78131AS
    (S)-(+)-Ibuprofen D3

    (S)-ibuprofen d3

    		 COX Inflammation/Immunology
    (S)-(+)-Ibuprofen-d3 is a deuterium labeled (S)-(+)-Ibuprofen. (S)-(+)-Ibuprofen is the S(+)-enantiomer of Ibuprofen that inhibits COX-1 and COX-2 activity with IC50s of 2.1 μM and 1.6 μM. (S)-(+)-Ibuprofen has analgesic, antiinflammatory and antipyretic effects[1][2].
    (S)-(+)-Ibuprofen D3
  • HY-78131A
    (S)-(+)-Ibuprofen

    Dexibuprofen

    		 COX Inflammation/Immunology Cancer
    (S)-(+)-Ibuprofen ((S)-Ibuprofen), a S(+)-enantiomer of Ibuprofen, is a potent COX-1 and COX-2 inhibitor with IC50s of 2.1 μM and 1.6 μM, respectively. (S)-(+)-Ibuprofen has analgesic, anti-inflammatory, anticancer and antipyretic effects .
    (S)-(+)-Ibuprofen
  • HY-121899R
    1-Oxo Ibuprofen (Standard)

    		Drug Metabolite Others
    1-Oxo Ibuprofen (Standard) is the analytical standard of 1-Oxo Ibuprofen. This product is intended for research and analytical applications. 1-Oxo Ibuprofen (Ibuprofen EP impurity J) is a degradation product and a potential impurity in preparations of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively .
    1-Oxo Ibuprofen (Standard)
  • HY-126121R
    2-Hydroxy Ibuprofen (Standard)

    		COX Inflammation/Immunology Cancer
    2-Hydroxy Ibuprofen (Standard) is the analytical standard of 2-Hydroxy Ibuprofen. This product is intended for research and analytical applications. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.
    2-Hydroxy Ibuprofen (Standard)
  • HY-126121S
    2-Hydroxy Ibuprofen-d6

    (±)-2-Hydroxy ibuprofen-d6

    		 Isotope-Labeled Compounds COX Inflammation/Immunology Cancer
    2-Hydroxy Ibuprofen-d6 is the deuterium labeled 2-Hydroxy Ibuprofen. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2].
    2-Hydroxy Ibuprofen-d6
  • HY-131391
    m-Isobutyl Ibuprofen

    		Drug Intermediate Others
    m-Isobutyl Ibuprofen (Compound IMP-A) is the impurity found during synthesis of Ibuprofen (HY-78131) .
    m-Isobutyl Ibuprofen
  • HY-136592
    1-Hydroxy-ibuprofen

    		COX Inflammation/Immunology Cancer
    1-Hydroxy Ibuprofen is a metabolite of Ibuprofen in P. australis . Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively .
    1-Hydroxy-ibuprofen
  • HY-W087194
    p-Ethylhydratropic acid

    		COX Inflammation/Immunology
    p-Ethylhydratropic acid (compound 5b) is the impurity of Ibuprofen (HY-78131). Ibuprofen is a potent, orally active, selective COX-1 inhibitor .
    p-Ethylhydratropic acid
  • HY-152535
    ATV041

    		HSV Infection Inflammation/Immunology
    ATV041 is an orally active Ibuprofen (HY-78131) and nucleotide analogue. ATV041 improves oral pharmacokinetic (PK) profile and tissue distribution with anti-mouse hepatitis virus (MHV) activity. ATV041 reduces viral load, tissue damage and virus-induced inflammation in a dose-dependent manner .
    ATV041
  • HY-W040672
    Ibufenac

    Dytransin

    		 COX Inflammation/Immunology
    Ibufenac (Dytransin) is an analog of Ibuprofen. Ibuprofen is a non-steroidal anti-rheumatoid agen and non-selective COX inhibitor used to research mild-moderate pain, fever, and inflammation.
    Ibufenac
  • HY-W121901
    Naproxen glucuronide

    (S)-Naproxen-β-D-glucuronide

    		 COX Inflammation/Immunology
    Naproxen glucuronide ((S)-Naproxen-β-D-glucuronide) is a non-selective COX inhibitor. Naproxen glucuronide, a metabolite of naproxen, is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same as ibuprofen) that relieves pain, fever, swelling, and stiffness .
    Naproxen glucuronide
  • HY-W702781
    1,3-Distearin

    1,3-Distearoyl glycerol; Glyceryl 1,3-distearate; DG(18:0/0:0/18:0)

    		 Drug Intermediate Inflammation/Immunology
    1,3-Distearin (1,3-Distearoyl glycerol) is an intermediate for synthesizing non-steroidal anti-inflammatory agents, and can be used in the synthesis of Ibuprofen (HY-78131), Naproxen (HY-15030), Diclofenac (HY-15036), and other non-steroidal anti-inflammatory agents .
    1,3-Distearin
  • HY-19500
    SC-75416

    		COX Others
    SC-75416 is a selective cyclooxygenase-2 inhibitor. Its pharmacokinetic/pharmacodynamic (PK/PD) model was used for development and clinical trial simulation to design a study protocol to verify its analgesic effect in a post-oral surgery pain model. The simulation results showed that 360 mg of SC-75416 may provide better pain relief than 400 mg of ibuprofen. The actual clinical trial results confirmed this hypothesis, and 360 mg of SC-75416 was indeed superior to 400 mg of ibuprofen in pain relief. The PK/PD model of SC-75416 showed good predictive performance and successfully predicted its clinical effect. These research results show that SC-75416, as a new selective COX-2 inhibitor, has potential clinical application value in the management of post-oral surgery pain.
    SC-75416
  • HY-159702
    Eudragit RS 100

    		Mucin Others
    Eudragit RS 100 is a mucoadhesive, nonbiodegradable positively charged polymer,which can be used for research of developing nanoparticles (NPs) for the ophthalmic and oral administration of Ibuprofen (HY-78131) and Cyclosporins (HY-100731), as well as nano- and micro-fibres used as scaffolds. Eudragit RS 100 NPs interacts efficiently with mucin and promotes glutathione (GSH) transmucosal absorption .
    Eudragit RS 100
  • HY-N6613
    Polygalacturonic acid

    Galacturonic acid polymer

    		 Others Infection Inflammation/Immunology
    Polygalacturonic acid (Galacturonic acid polymer) is transparent colloid, is a major component of the cell wall. Polygalacturonic acid can be used to prepare silver nanoparticles (AgNPs), as an antioxidant and anti-inflammatory that protect cells from destructive effect of elevated ROS and accelerate wound healing. Polygalacturonic acid nanoparticles also displays anti-bacterial activity .
    Polygalacturonic acid

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