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Results for "

methyl methanesulfonate

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

2

Biochemical Assay Reagents

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W004702
    Methyl methanesulfonate

    		DNA Alkylator/Crosslinker Necroptosis MDM-2/p53 Reactive Oxygen Species Others
    Methyl methanesulfonate is an alkylating agent which transfers methyl groups, and induces DNA damage. Methyl methanesulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
    Methyl methanesulfonate
  • HY-W004702R
    Methyl methanesulfonate (Standard)

    		Biochemical Assay Reagents Others
    Methyl methanesulfonate (Standard) is the analytical standard of Methyl methanesulfonate. This product is intended for research and analytical applications. Methyl methanesulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Methyl methanesulfonate (Standard)
  • HY-Z7147
    Efinaconazole analogue-1

    		Biochemical Assay Reagents Others
    1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate (Efinaconazole Impurity) is a biological molecule.
    Efinaconazole analogue-1
  • HY-W004702S
    Methyl methanesulfonate-d3

    methylMETHANE SULPHONATE-d3

    		 Isotope-Labeled Compounds Others
    Methyl methanesulfonate-d3 is the deuterium labeled Methyl methanesulfonate[1].
    Methyl methanesulfonate-d3
  • HY-170825
    (trans-4-Ethynylcyclohexyl)methyl methanesulfonate

    		PROTAC Linkers Cancer
    (trans-4-Ethynylcyclohexyl)methyl methanesulfonate is the linker that can be used for synthesis of PROTAC degrader SMD-3236 (HY-170824) .
    (trans-4-Ethynylcyclohexyl)methyl methanesulfonate
  • HY-119993
    AR03

    BMH-23

    		 DNA/RNA Synthesis Cancer
    AR03 (BMH-23) is an apurinic/apyrimidinic endonuclease 1 (Ape1) inhibitor with an IC50 of 2.1 µM. AR03 has low affinity for double-stranded DNA. AR03 potentiates the cytotoxicity of methyl methanesulfonate and temozolomide in SF767 cells .
    AR03
  • HY-170824
    SMD-3236

    		PROTACs Epigenetic Reader Domain Cancer
    SMD-3236 is a SMARCA2-targeted PRAOTAC degrader designed based on SMARCA ligands and VHL-1 ligands, with long-lasting antitumor activity in vivo. SMARCA2 is a synthetic lethal target in SMARCA4-deficient cancer cells, and SMD-3236 has a 2000-fold selectivity for degradation of SMARCA2 over SMARCA4, with a DC50< 1 nM and a Dmax>95%. SMD-3236 can induce SMARCA2 loss in tumor tissues while retaining SMARCA4 protein, and inhibit tumor growth in the H838 smarca4-deficient human cancer xenograft model. SMD-3236 is composed of target protein ligand (red part) SMI-1074 (HY-170817), PROTAC linker (black part) (trans-4-Ethynylcyclohexyl)methyl methanesulfonate (HY-170825), and E3 ligase ligand (blue part) SMARCA2 ligand-14 (HY-170826), of which the E3 ligase ligand and linker form a conjugate E3 Ligase Ligand-linker Conjugate 159 (HY-170827) .
    SMD-3236

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