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post-antibiotic effect

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (2) Bacterial (3) Beta-lactamase (1) Isotope-Labeled Compounds (1) Reactive Oxygen Species (1)
By Research Areas:	Infection (4)

Inhibitors & Agonists

Isotope-Labeled Compounds

Targets Recommended: Antibiotic

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0479

Thiamphenicol Thiophenicol; Dextrosulphenidol	Beta-lactamase Bacterial Antibiotic	Infection
Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial *antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect* (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .

HY-168960

ROS inducer 8	Reactive Oxygen Species Bacterial	Infection
ROS inducer 8 (Compound 11g) is the inhibitor for glutathione (GSH), that induces the ROS accumulation in Enterococcus faecalis, thereby exhibiting antibacterial activity. ROS inducer 8 disrupts the biofilm, inhibits S. aureus and E. faecalis with MIC of 8 μg/mL and 2 μg/mL, exhibits post-antibiotic effect. ROS inducer 8 exhibits low hemolytic toxicity to sheep erythrocytes (HC₅₀ > 1280 μg/mL) .

HY-106668

Isepamicin Sch 21420	Antibiotic Bacterial	Infection
Isepamicin (Sch 21420) is an aminoglycoside antibacterial. Isepamicin has better activity against strains producing type I 6'-acetyltransferase. Isepamicin’s antibacterial spectrum includes Enterobacteriaceae and staphylococci. Anaerobes, Neisseriaceae and streptococci are resistant. Isepamicin exhibits a strong concentration-dependent bactericidal effect, a long post-antibiotic effect (several hours) and induces adaptive resistance .

HY-B0479S1

Thiamphenicol-d3-1 Thiophenicol-d₃-1; Dextrosulphenidol-d₃-1	Isotope-Labeled Compounds	Infection
Thiamphenicol-d₃-1 (Thiophenicol-d₃-1; Dextrosulphenidol-d₃-1) is the deuterium-labeled Thiamphenicol (HY-B0479) . Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial *antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect* (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .

Cat. No.	Product Name	Chemical Structure

HY-B0479S1

Thiamphenicol-d3-1
Thiamphenicol-d₃-1 (Thiophenicol-d₃-1; Dextrosulphenidol-d₃-1) is the deuterium-labeled Thiamphenicol (HY-B0479) . Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial *antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect* (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .

Thiamphenicol-d3-1

Thiamphenicol-d₃-1 (Thiophenicol-d₃-1; Dextrosulphenidol-d₃-1) is the deuterium-labeled Thiamphenicol (HY-B0479) . Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .

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