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Results for "

skin tumor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Apoptosis (4) Bacterial (5) Biochemical Assay Reagents (2) COX (4) DNA/RNA Synthesis (2) EBV (1) Endogenous Metabolite (3) Ferroptosis (2) HBV (2) HCV (2) Histamine Receptor (1) MMP (1) Necroptosis (1) Organoid (1) Parasite (2) Photosensitizer (2) PKC (1) Sirtuin (2) TGF-beta/Smad (2) Tyrosinase (1) Wnt (1)
By Research Areas:	Cancer (26) Cardiovascular Disease (4) Endocrinology (2) Infection (11) Inflammation/Immunology (6) Neurological Disease (4)
Oligonucleotides:	Antisense Oligonucleotides (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Oligonucleotides

Targets Recommended: TNF Receptor BRK

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-18985

Phorbol 12,13-dibutyrate 3 Publications Verification Phorbol dibutyrate; PDBu	PKC	Cancer
Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator and a potent skin tumor promoter .

HY-142118A

Trabedersen sodium AP 12009 sodium	TGF-beta/Smad	Cancer
Trabedersen sodium is an antisense oligodeoxynucleotide that specifically inhibits TGF-β2 (TGF-beta/Smad). Trabedersen sodium can be used for the study of malignant brain tumors and other solid tumors overexpressing TGF-β2, such as those of the skin, pancreas and colon .

HY-14617

Paradol 3 Publications Verification [6]-Gingerone; [6]-Paradol	COX	Cancer
Paradol is a pungent phenolic substance found in ginger and other Zingiberaceae plants. Paradol is an effective inhibitor of tumor promotion in mouse skin carcinogenesis, binds to cyclooxygenase (COX)-2 active site.

HY-B1461

Deoxyarbutin	Tyrosinase Apoptosis	Cancer
Deoxyarbutin is an orally active tyrosinase inhibitor that can promote apoptosis of melanoma cells, enhance the vitality of mouse acinar cells, and has skin whitening and anti-tumor activity ^[1][2][3].

HY-P5604

Maximin 1	Bacterial	Infection
Maximin 1 is an antimicrobial peptide derived from skin secretions of Bombina maxima. Maximin 1 has cytotoxicity on tumor cells and spermicidal effect .

HY-P5605

Maximin 2	Bacterial	Infection
Maximin 2 is an antimicrobial peptide derived from skin secretions of Bombina maxima. Maximin 2 has cytotoxicity on tumor cells and spermicidal effect .

HY-P5608

Maximin 4	Bacterial	Infection
Maximin 4 is an antimicrobial peptide derived from skin secretions of Bombina maxima. Maximin 4 has cytotoxicity on tumor cells and spermicidal effect .

HY-P5609

Maximin 5	Bacterial	Infection
Maximin 5 is an antimicrobial peptide derived from skin secretions of Bombina maxima. Maximin 5 has cytotoxicity on tumor cells and spermicidal effect .

HY-126931

Dinophysistoxin 1 DTX 1	Endogenous Metabolite	Cancer
Dinophysistoxin 1 (DTX 1, 35-methylokadaic acid) is a causative agent of diarrhetic shellfish poisoning. Dinophysistoxin 1 exerts tumor-promoting activity, serves as a skin irritant as well .

HY-N7563

α-Toxicarol	EBV	Infection Cancer
α-Toxicarol is a potent inhibitor of EBV.α-Toxicarol significantly inhibits mouse skin tumor in vivo. α-Toxicarol inhibits the TPA-induced EBV-EA activation .

HY-142118

Trabedersen AP 12009	TGF-beta/Smad	Cancer
Trabedersen (AP 12009) is an antisense oligodeoxynucleotide that specifically inhibits TGF-β2 (TGF-beta/Smad). Trabedersen can be used for the study of malignant brain tumors and other solid tumors overexpressing TGF-β2, such as those of the skin, pancreas and colon .

HY-P5606

Maximin 3	Bacterial	Infection
Maximin 3 is an antimicrobial peptide derived from skin secretions of Bombina maxima. Maximin 3 has cytotoxicity on tumor cells and spermicidal effect. Maximin 3 has significant anti-HIV activity .

HY-W543743

1-Ethenylpyrene 1-Vinylpyrene	Biochemical Assay Reagents	Cancer
1-Ethenylpyrene (1-Vinylpyrene) is an anti-chemical carcinogen that inhibits the formation of skin tumors initiated by either DMBA (HY-W011845) or Benzo[a]pyrene (HY-107377) .

HY-N0769

Isopimpinellin 1 Publications Verification	DNA/RNA Synthesis Parasite	Infection Inflammation/Immunology Cancer
Isopimpinellin, an orally active compound isolated from Glomerella cingulata. Isopimpinellin blocks DNA adduct formation and skin tumor initiation by 7,12-dimethylbenz[a]anthracene. Isopimpinellin possesses anti-leishmania effect .

HY-156551

Porcn-IN-2	Wnt	Cancer
Porcn-IN-2 (Example 107) is a Wnt inhibitor, with an IC₅₀ value of 0.05 nM. Porcn-IN-2 can be used for research of cancer, sarcoma, melanoma, skin cancer, haematological tumors, lymphoma, carcinoma, and leukemia, etc .

HY-146416

Antitumor photosensitizer-2	Photosensitizer	Cancer
Antitumor photosensitizer-2 (Compound 11) is a potent photosensitizer. Antitumor photosensitizer-2 has outstanding photodynamic anti-tumor effects without obvious skin photo-toxicity, and can act as new agent candidates for photodynamic research .

HY-146414

Antitumor photosensitizer-1	Photosensitizer	Cancer
Antitumor photosensitizer-1 (Compound 8) is a potent photosensitizer. Antitumor photosensitizer-1 has outstanding photodynamic anti-tumor effects without obvious skin photo-toxicity, and can act as new agent candidates for photodynamic research .

HY-N1687

21,24-Epoxycycloartane-3,25-diol	Others	Others
21,24-Epoxycycloartane-3,25-diol (compound 15 or 16) is a cycloartanoid triterpene that can be isolated from the leaves of Lansium domesticum. 21,24-Epoxycycloartane-3,25-diol inhibits skin-tumor promotion .

HY-14617R

Paradol (Standard)	COX	Cancer
Paradol (Standard) is the analytical standard of Paradol. This product is intended for research and analytical applications. Paradol is a pungent phenolic substance found in ginger and other Zingiberaceae plants. Paradol is an effective inhibitor of tumor promotion in mouse skin carcinogenesis, binds to cyclooxygenase (COX)-2 active site.

HY-147521

Antitumor photosensitizer-3	Necroptosis	Cancer
Antitumor photosensitizer-3 (Compound I) is a chlorin derivative. Antitumor photosensitizer-3 induces tumor cells apoptosis and necrosis under 650 nm laser irradiation. Antitumor photosensitizer-3 exhibits lower skin photo-toxicity than positive reference m-THPC in vivo .

HY-N0769R

Isopimpinellin (Standard)	DNA/RNA Synthesis Parasite	Infection Inflammation/Immunology Cancer
Isopimpinellin (Standard) is the analytical standard of Isopimpinellin. This product is intended for research and analytical applications. Isopimpinellin, an orally active compound isolated from Glomerella cingulata. Isopimpinellin blocks DNA adduct formation and skin tumor initiation by 7,12-dimethylbenz[a]anthracene. Isopimpinellin possesses anti-leishmania effect .

HY-W587468

all-trans-3,4-Didehydro retinoic acid 3,4-DHRA	Biochemical Assay Reagents
All-trans-3,4-Didehydro retinoic acid (3,4-DHRA) is a compound with gene-regulating activity that binds to retinoic acid receptors (RARs) and triggers receptor activation. All-trans-3,4-Didehydro retinoic acid plays an important role in skin development and differentiation and has potential anti-tumor and anti-inflammatory properties. All-trans-3,4-Didehydro retinoic acid is also being studied for the inhibition of a variety of diseases, including skin diseases and certain types of cancer.

HY-107063

AHR-1911 10-Undecen-1-yl-thiopseudourea iodide	Histamine Receptor	Cancer
AHR-1911 (10-Undecen-1-yl-Thiopseudourea Iodide;Isothiuronium) is a thiourea-based anti-inflammatory and anti-tumor agent that has an improving effect on burned skin. AHR-1911 produces histamine-like effects when injected intradermally and may reduce arterial pressure in anesthetized dogs. AHR-1911 inhibits tumor growth and reduces microsomal and C-polysome protein synthesis .

HY-119846

Afromosin	Others	Cancer
Afromosin is an isoflavone, that can be isolated from Millettia dielsiana Harms. Afromosin exhibits remarkable tumor inhibitory effects .

HY-B0568

Deferiprone 35+ Cited Publications	Ferroptosis HCV Apoptosis COX	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Endocrinology Cancer
Deferiprone is a potent, orally active, brain-penetrant, cell-penetrant, skin-permeable, free iron chelating agent. Deferiprone inhibits the proliferation and migration, and stimulates apoptosis in tumor cell. Deferiprone has antianemic, neuroprotective, anti-inflammatory, antioxidant, and antidotal activity. Deferiprone can be used in cancer, cardiovascular disease, infection, inflammation, and neurological disease study .

HY-B1231

Heptaminol hydrochloride RP-2831 hydrochloride	Adrenergic Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Heptaminol (RP-2831) hydrochloride is a vasoconstrictor used in the study of hypotension, especially orthostatic hypotension. Heptaminol is also a skin cancer proliferation inhibitor that inhibits immune inflammation induced by the tumor promoting factor 12-O-tetradecanoylphorbol-13-acetate (TPA) in an NO-dependent manner. Heptaminol also acts as a sympathomimetic amine, exerting indirect sympathetic effects. Heptaminol is also an antagonist of catecholamine release and uptake and can increase intracellular free calcium levels .

HY-B0150

Nicotinamide Maximum Cited Publications 52 Publications Verification Niacinamide; Nicotinic acid amide	Organoid Endogenous Metabolite Sirtuin HBV	Cancer
Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC₅₀: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD₊, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity .

HY-B0150A

Nicotinamide Hydrochloride Niacinamide Hydrochloride; Nicotinic acid amide Hydrochloride	Sirtuin Endogenous Metabolite HBV	Infection Cancer
Nicotinamide Hydrochloride is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC₅₀: 2 μM). Nicotinamide Hydrochloride also inhibits SIRT1. Nicotinamide Hydrochloride increases cellular NAD₊, ATP, ROS levels. Nicotinamide Hydrochloride inhibits tumor growth and improves survival. Nicotinamide Hydrochloride also has anti-HBV activity .

HY-B0568R

Deferiprone (Standard)	Ferroptosis HCV Apoptosis COX	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Endocrinology Cancer
Deferiprone (Standard) is the analytical standard of Deferiprone. This product is intended for research and analytical applications. Deferiprone is a potent, orally active, brain-penetrant, cell-penetrant, skin-permeable, free iron chelating agent. Deferiprone inhibits the proliferation and migration, and stimulates apoptosis in tumor cell. Deferiprone has antianemic, neuroprotective, anti-inflammatory, antioxidant, and antidotal activity. Deferiprone can be used in cancer, cardiovascular disease, infection, inflammation, and neurological disease study .

HY-19671

Apomine SR-45023A; SR 9223i; SK&F-99085	Apoptosis	Cancer
Apomine (SR-45023A) is an antineoplastic agent that inhibits the mevalonate/isoprenoid pathway in cholesterol synthesis. Apomine can accelerate the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR). Apomine can also inhibit the growth of various types of cancer cells, including lung cancer, colon cancer, breast cancer, and skin cancer. In addition, Apomine is able to induce apoptosis in tumor cell lines derived from leukemia, colon cancer, liver cancer, ovarian cancer, and breast cancer .

HY-E70005I

Collagenase, Type VI Type VI collagenase	MMP	Cancer
Collagenase, Type VI (EC 3.4.24.3) is a collagenase that can degrade type VI collagen. Type VI collagen is a component of cell membranes in various tissues (such as skin, heart, blood vessels, cartilage, and synovial fluid). Excessive collagenase can cause extracellular matrix lesions. Collagenase is also a biomarker for tumor invasion and metastasis. Collagenase, Type VI can specifically act on the peptide bond between proline and glycine. This feature can be used to quickly and sensitively detect its concentration level in experiments using corresponding modified electrodes .

HY-B1231R

Heptaminol (hydrochloride) (Standard)	Others	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Heptaminol (hydrochloride) (Standard) is the analytical standard of Heptaminol (hydrochloride). This product is intended for research and analytical applications. Heptaminol (RP-2831) hydrochloride is a vasoconstrictor used in the study of hypotension, especially orthostatic hypotension. Heptaminol is also a skin cancer proliferation inhibitor that inhibits immune inflammation induced by the tumor promoting factor 12-O-tetradecanoylphorbol-13-acetate (TPA) in an NO-dependent manner. Heptaminol also acts as a sympathomimetic amine, exerting indirect sympathetic effects. Heptaminol is also an antagonist of catecholamine release and uptake and can increase intracellular free calcium levels .

Cat. No.	Product Name	Type

HY-W587468

all-trans-3,4-Didehydro retinoic acid 3,4-DHRA	Cell Assay Reagents
All-trans-3,4-Didehydro retinoic acid (3,4-DHRA) is a compound with gene-regulating activity that binds to retinoic acid receptors (RARs) and triggers receptor activation. All-trans-3,4-Didehydro retinoic acid plays an important role in skin development and differentiation and has potential anti-tumor and anti-inflammatory properties. All-trans-3,4-Didehydro retinoic acid is also being studied for the inhibition of a variety of diseases, including skin diseases and certain types of cancer.

all-trans-3,4-Didehydro retinoic acid

3,4-DHRA

Cell Assay Reagents

All-trans-3,4-Didehydro retinoic acid (3,4-DHRA) is a compound with gene-regulating activity that binds to retinoic acid receptors (RARs) and triggers receptor activation. All-trans-3,4-Didehydro retinoic acid plays an important role in skin development and differentiation and has potential anti-tumor and anti-inflammatory properties. All-trans-3,4-Didehydro retinoic acid is also being studied for the inhibition of a variety of diseases, including skin diseases and certain types of cancer.

Cat. No.	Product Name	Target	Research Area