2. Signaling Pathways
  3. Apoptosis
  4. Photosensitizer

Photosensitizer

 

Photosensitizer Related Products (18):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-16477
    Talaporfin sodium
    		99.74%
    Talaporfin (ME2906) sodium is a chlorin based photosensitizer. Talaporfin sodium can be used for the research of various cancers by using photodynamic therapy (PDT).
    Talaporfin sodium
  • HY-145241
    TBTDC
    		98.64%
    TBTDC is a highly efficient multifunctional organic photosensitizer with aggregation-induced emission for in vivo bioimaging and photodynamic research.
    TBTDC
  • HY-147690
    Photosensitizer-2
    Photosensitizer-2 (compound 1) is a organic D-π-A sensitizer against phototoxicity. Photosensitizer-2 contains an acrylic acid moiety that exerts high levels of phototoxicity. Photosensitizer-2 shows antitumor activity against HeLa cells, with IC50 values of 20.9 ± 4.5 μM (dark) and 0.046 ± 0.012 μM (irradiation), respectively.
    Photosensitizer-2
  • HY-19873
    SL-052
    SL-052 is a hypocrellin-based photosensitizer that has recently shown promising results in clinical and preclinical testing for cancer photodynamic therapy (PDT). SL-052 is encapsulated in biodegradable polylactic-co-glycolic acid (PLGA) polymer nanoparticles optimized using single emulsion solvent evaporation technology. The SL-052-PLGA nanoparticles were more effective in PDT treatment of subcutaneous SCCVII squamous cell carcinoma compared to polyvinylpyrrolidone (PVP)-based and standard liposomal SL-052 formulations. A longer time interval between drug injection and tumor illumination can improve tumor cure rates, and SL-052-PLGA nanoparticles showed the best therapeutic effect among all SL-052 formulations.
    SL-052
  • HY-126841
    5-Methoxysterigmatocystin
    5-Methoxysterigmatocystin is a mycotoxin with cytotoxic and genotoxic properties. 5-Methoxysterigmatocystin exhibits cytotoxicity against cancer cells A549 and HepG2 (IC50 of 5.5 and 0.7 μM), and induces DNA damage. 5-Methoxysterigmatocystin is a photosensitizer, which utilizes the visible to generate singlet oxygen (1O2).
    5-Methoxysterigmatocystin
  • HY-164294
    Aluminum phthalocyanine disulfonate
    Aluminum phthalocyanine disulfonate is a potential photosensitizer used for the research of Sonodynamic therapy (SDT).
    Aluminum phthalocyanine disulfonate
  • HY-162825
    Antitumor photosensitizer-7
    Antitumor photosensitizer-7 (compound 15) is a photosensitizer with anti-cancer activity. Antitumor photosensitizer-7 exhibits significant cytotoxicity against the G361 melanoma cell line under 414 nm blue light irradiation.
    Antitumor photosensitizer-7
  • HY-137474
    Purpurin 18 methyl ester
    Purpurin 18 methyl ester, a chlorophyll-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT). Purpurin 18 methyl ester has photodynamic activity to induce cancer cell death.
    Purpurin 18 methyl ester
  • HY-146416
    Antitumor photosensitizer-2
    Antitumor photosensitizer-2 (Compound 11) is a potent photosensitizer. Antitumor photosensitizer-2 has outstanding photodynamic anti-tumor effects without obvious skin photo-toxicity, and can act as new agent candidates for photodynamic research.
    Antitumor photosensitizer-2
  • HY-162129
    Antitumor agent-131
    Antitumor agent-131 (Compound 2-p) is an ER fluorescent probe with an IC50 value of 23 nM for HepG2 tumor cells. Antitumor agent-131 can be used as a photosensitizer for the study of cancer photodynamics.
    Antitumor agent-131
  • HY-128419
    Biguanidinium-porphyrin
    Biguanidinium-porphyrin is a mitochondria-targeting photosensitizer. Biguanidinium-porphyrin distributes within cell membranes with a large component in vesicles that correlated to some extent with the lysosomes and, upon longer exposures, in mitochondria and the cytosolic membrane.
    Biguanidinium-porphyrin
  • HY-146414
    Antitumor photosensitizer-1
    Antitumor photosensitizer-1 (Compound 8) is a potent photosensitizer. Antitumor photosensitizer-1 has outstanding photodynamic anti-tumor effects without obvious skin photo-toxicity, and can act as new agent candidates for photodynamic research.
    Antitumor photosensitizer-1
  • HY-161341
    β-Glucuronidase responsive conjugate 1
    β-Glucuronidase responsive conjugate 1 (compound 3) is a well-balanced photosensitizer which has photodynamic activity. β-Glucuronidase responsive conjugate 1 inhibits T-24 cell viability and growth with an IC50 of 0.2 μM. β-Glucuronidase responsive conjugate 1 can used to study bladder cancers.
    β-Glucuronidase responsive conjugate 1
  • HY-W738979
    Silicon naphthalocyanine dichloride
    Silicon naphthalocyanine dichloride is a photosensitizer with potential anti-tumor activity. Silicon naphthalocyanine dichloride is used as a cancer-inhibiting compound in photodynamic therapy. Silicon naphthalocyanine dichloride can effectively absorb light energy of a specific wavelength, thereby generating oxygen free radicals that help destroy cancer cells. The biocompatibility of Silicon naphthalocyanine dichloride makes it show good prospects in medical applications.
    Silicon naphthalocyanine dichloride
  • HY-W504836
    Deuteroporphyrin IX dihydrochloride
    Deuteroporphyrin IX (dihydrochloride) is a photosensitizer with high lipophilicity and amphiphilicity, capable of providing photosensitivity for cell membrane systems. Deuteroporphyrin IX (dihydrochloride) can induce irreversible discharge elimination in individual neurons.
    Deuteroporphyrin IX dihydrochloride
  • HY-W011577
    Benzo[f]tetraphene
    Benzo[f]tetraphene (Dibenz[a,c]anthracene) is a polycyclic aromatic hydrocarbon with significant antitumor activity. Benzo[f]tetraphene is used as a luminescent probe in cell biology research and can effectively detect reactive oxygen species in biological systems. Benzo[f]tetraphene can also be used as a potential photosensitizer and shows good application prospects in photodynamic inhibition.
    Benzo[f]tetraphene
  • HY-W010713
    Meso-tetraphenylchlorin
    Meso-tetraphenylchlorin (TPCS2a) is a photosensitizer with poor water solubility, which limits its use in the blood circulation. However, TPCS2a@NPs nanoparticles can be prepared based on polylactic-co-polyethylene glycol acid (PLGA) polymer core loaded with TPCS2. Such nanoparticles can be coated with mesenchymal stem cell-derived plasma membranes (mMSCs) to form mMSC-TPCS2a@NPs, which prolongs blood circulation time and improves tumor targeting ability. Compared with uncoated TPCS2a@NPs, mMSC-TPCS2a@NPs can reduce macrophage uptake by 54% to 70% under different conditions. Both nanoparticle forms are effectively accumulated in MCF7 and MDA-MB-231 breast cancer cells, while uptake in normal breast epithelial cells MCF10A is significantly lower.
    Meso-tetraphenylchlorin
  • HY-157051
    [Ru(DIP)2TAP]Cl2
    [Ru(DIP)2TAP]Cl2, Ruthenium(II) polypyridyl compound, is a photosensitizer. [Ru(DIP)2TAP]Cl2 can be used for the research of photodynamic therapy (PDT).
    [Ru(DIP)2TAP]Cl2