Search Result
Results for "
sn-1
" in MedChemExpress (MCE) Product Catalog:
10
Biochemical Assay Reagents
4
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-141572
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sn-1,2-Dioleoylglycerol
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Biochemical Assay Reagents
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Others
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ALN29882 is a glycerolipid located on the plasma membrane. It consists of two fatty acid chains covalently linked to a single glycerol molecule by means of an ester bond. 18:1 DG has been used as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay. It is also used as a substrate in the DGAT-1 enzyme assay to evaluate compounds as potential inhibitors of DGAT-1. Suitable for lipoprotein overlay screening assays with the recombinant protein His-AtROP6.
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- HY-138815S
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Isotope-Labeled Compounds
Glycosidase
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Metabolic Disease
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(S)-N-(1H-Indole-3-acetyl)tryptophan-d4 is deuterium labeled (S)-N-(1H-Indole-3-acetyl)tryptophan. (S)-N-(1H-Indole-3-acetyl)tryptophan (compound 4a) is a Tryptophan derivative that weakly inhibits β-D-glucosidase [1] .
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- HY-W128037
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- HY-138815
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Glycosidase
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Metabolic Disease
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(S)-N-(1H-Indole-3-acetyl)tryptophan (compound 4a) is a Tryptophan derivative that weakly inhibits β-D-glucosidase [1].
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- HY-141642
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Glycerol triheptadecanoate; Trimargarin
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Others
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Others
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Triheptadecanoin is a triacylglycerol that contains heptadecanoic acid at the sn-1, sn-2, and sn-3 positions [1].
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- HY-N9444
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Triglyceride PLP,sn
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Endogenous Metabolite
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Metabolic Disease
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1,3-Dipalmitoyl-2-linoleoyl glycerol is a triacylglycerol that contains Palmitic acid at the sn-1 and sn-3 positions and Linoleic acid.
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- HY-157741
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Lipase
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Others
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1-Myristoyl-2-oleoyl-3-palmitoyl-rac-glycerol (MOP) is a triacylglycerol containing myristic acid (HY-N2041), oleic acid (HY-N1446) and palmitic acid (HY-N0830) at the sn-1, sn-2 and sn-3 positions, respectively [1].
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- HY-W440957
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PC(16:0/14:0); 1-palmitoyl-2-myristoyl-sn-glycero-3-phosphocholine
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Liposome
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Cancer
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PMPC is a phosphatidylcholine with asymmetrical fatty acid. Palmitic acid occupies sn-1 position while myristic acid is placed at the sn-2 position.
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- HY-170679
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- HY-W780175
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- HY-172020
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- HY-168787
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- HY-170619
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- HY-170637
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- HY-170677
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- HY-170639
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- HY-W440981
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1-Stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine
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Liposome
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Cancer
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SPPC is a phospholipid with different length of fatty acid. The sn-1 position contains a stearic acid (18:0) while the sn-2 position is occupied by a palmitic acid (16:0).
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- HY-168797
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- HY-168785
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Drug Derivative
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Others
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1,3-Dilinoelaidoyl glycerol is a diacylglycerol. 1,3-Dilinoelaidoyl glycerol contains Linoleic acid (HY-N0729) at sn-1 and sn-3 positions.
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- HY-N7859
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1,3-Dioleoyl-2-myristoyl-rac-glycerol
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Lipase
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Others
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1,3-Dioleoyl-2-myristoyl glycerol is a triacylglycerol that contains oleic acid at the sn-1 and sn-3 positions and myristic acid at the sn-2 position [1].
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- HY-W800733
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1,2-Dilauroyl-sn-glycero-3-phosphorylglycerol; PG(12:0/12:0)
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Liposome
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Cancer
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DLPG is a phospholipid containing lauric acid (12 chain fatty acid) inserted at the sn-1 and sn-2 positions. Its phosphate group is attached to glycerol. It is used in the generation of micelles, liposomes, and other artificial membranes.
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- HY-W674124
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TG(15:0/15:0/15:0); 1,2,3-Tripentadecanoyl glycerol
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Endogenous Metabolite
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Metabolic Disease
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Tripentadecanoin (TG(15:0/15:0/15:0)) is a triacylglycerol that contains pentadecanoic acid (HY-W004283) at the sn-1, sn-2, and sn-3 positions.
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- HY-170632
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1,2,3-Tri-6(Z)-octadecenoyl glycerol
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Biochemical Assay Reagents
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Metabolic Disease
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Tripetroselinin (1,2,3-Tri-6(Z)-octadecenoyl glycerol) is a triacylglycerol that contains Petroselinic acid (HY-113362) at the sn-1, sn-2, and sn-3 positions.
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- HY-W019833
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PC(14:0/18:0); 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine
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Endogenous Metabolite
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Metabolic Disease
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MSPC is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a stearic acid (18:0) at the sn-2 position. It can self assemble in water to form lipid bilayers. Reagent grade, for research purpose.
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- HY-170618
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- HY-170625
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- HY-170628
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- HY-170635
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Biochemical Assay Reagents
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Metabolic Disease
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1-Palmitoyl-3-arachidoyl-rac-glycerol is a diacylglycerol that contains Palmitic acid (HY-N0830) at the sn-1 position and Arachidic acid (HY-W004260) at the sn-3 position
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- HY-170641
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- HY-170678
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Biochemical Assay Reagents
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Metabolic Disease
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1-Myristoyl-3-docosanoyl-rac-glycerol is a diacylglycerol that contains Myristic acid (HY-N2041) at the sn-1 position and Docosanoic acid (HY-W013049) at the sn-3 position.
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- HY-W440958
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PSPC; PC(16:0-18:0)
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Liposome
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Cancer
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1-Palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine is an assymetrical phospholipid containing saturated palmitic and stearic acid at the sn-1 and sn-2 position respectively. The phosphate group is attached to choline.
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- HY-170636
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- HY-170638
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- HY-W590536
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1-Palmitoyl-2-Lauroyl-sn-glycero-3-Phosphatidylcholine; 1-Palmitoyl-2-Lauroyl-sn-glycero-3-Phosphocholine
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Liposome
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Cancer
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1,2-PLPC is a phospholipid containing palmitoyl (16:0) and lauryl (12:0) acyl substituents at the sn-1 and sn-2 positions, respectively. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-W725327
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1,2-Dipropionyl-sn-glycero-3-Phosphatidylcholine; 1,2-Dipropionyl-sn-glycero-3-Phosphocholine; PC(3:0/3:0)
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Endogenous Metabolite
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Metabolic Disease
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1,2-Dipropionyl-sn-glycero-3-PC is a phospholipid containing propionic acid at the sn-1 and sn-2 positions. It has been used to study the interaction between water and the phosphocholine headgroup in aqueous solutions.
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- HY-157672
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Bacterial
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Others
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18:1-14:0 PC, an asymmetric phospholipid featuring an unsaturated acyl chain in the sn-1 position, can create a hydrophobic surface in mucus by functioning as a surfactant to impede bacterial penetrance, while also serving as a dietary source of choline.
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- HY-W440982
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PC(18:0/18:1); 2-?Oleoyl-?1-?stearoyl-?sn-?glycero-?3-?phosphocholine
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Liposome
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Others
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SOPC is an asymmetrical phospholipid with saturated fatty acid (stearic acid/18:0) at sn-1 position and unsaturated fatty acid (oleic acid/18:1) at sn-2 position. SOPC can be used for various biochemical studies [1].
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- HY-170631
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Biochemical Assay Reagents
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Metabolic Disease
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1,2-Dielaidoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains Elaidic acid (HY-113016) in the sn-1 and sn-2 positions and Palmitic acid (HY-N0830) in the sn-3 position.
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- HY-170633
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Biochemical Assay Reagents
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Metabolic Disease
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1,2-Dielaidoyl-3-stearoyl-rac-glycerol is a triacylglycerol that contains Elaidic acid (HY-113016) at the sn-1 and sn-2 positions and Stearic acid (HY-B2219) at the sn-3 position.
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- HY-170676
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Biochemical Assay Reagents
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Metabolic Disease
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1,3-Dilinoleoyl-2-docosahexaenoyl glycerol is a triacylglycerol that contains Linoleic acid (HY-N0729) at the sn-1 and sn-3 positions and Docosahexaenoic acid (HY-B2167) at the sn-2 position.
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- HY-170681
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Biochemical Assay Reagents
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Metabolic Disease
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1,3-Didocosanoyl-2-oleoyl glycerol is a triacylglycerol that contains Docosanoic acid (HY-W013049) at the sn-1 and sn-3 positions and Oleic acid (HY-N1446) at the sn-2 position.
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- HY-170680
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Biochemical Assay Reagents
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Metabolic Disease
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1,2-Dilinoleoyl-3-stearoyl-rac-glycerol is a triacylglycerol that contains Linoleic acid (HY-N0729) at the sn-1 and sn-2 positions and Stearic acid (HY-B2219) at the sn-3 position.
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- HY-W040185
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1,2-DPPA sodium; PA(14:0/14:0) sodium; 1,2-Dimyristoyl-sn-glycero-3-phosphate sodium
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Liposome
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Metabolic Disease
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1,2-Dimyristoyl-sn-glycero-3-phosphate monosodium is a phospholipid containing the long-chain (14:0) myristic acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-145541
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1,2-Dinonadecanoin
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Biochemical Assay Reagents
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Others
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12-Dinonadecanoyl-rac-glycerol is a diacylglycerol containing nonadecanoic acid (HY-W004261) at the sn-1 and sn-2 positions. Nonadecanoic acid is a 19-carbon long saturated fatty acid. Nonadecanoic acid is the major constituent of the substance secreted by Rhinotermes marginalis to defence [1].
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- HY-W482407
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(S)-2,3-Bis(hexadecyloxy)propan-1-ol
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Biochemical Assay Reagents
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Metabolic Disease
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1,2-O-Dihexadecyl-sn-glycerol ((S)-2,3-Bis(hexadecyloxy)propan-1-ol) is a saturated dialkyl glyceryl ether with hexadecyl groups at the sn-1 and sn-2 positions that mimics the structure of diacylglycerol.
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- HY-157618
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Bacterial
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Others
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18:0-18:1 PG sodium is a hydrogenated phospholipid that contributes to the stability of photosystem I and II protein complexes and plays a role in bacterial defense mechanisms, featuring two extra methylene groups in its saturated sn-1 chain, and is present in the thylakoid membranes of higher plants and cyanobacteria.
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- HY-W800805
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Liposome
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Cancer
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DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.
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- HY-N7953
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Endogenous Metabolite
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Metabolic Disease
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1,2-Dioleoyl-3-linoleoyl-rac-glycerol (OOL) is a triacylglycerol containing oleic acid at the sn-1 and sn-2 positions and linoleic acid at the sn-3 position. It is found in a variety of seed and vegetable oils, including pumpkin seed, olive, and sesame oils.
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- HY-113925
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1,2-DLPA Sodium; (2R)-2,3-bis(dodecanoyloxy)propyl hydrogen phosphate sodium
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Liposome
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Metabolic Disease
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1,2-Dilauroyl-sn-glycero-3-phosphate (1,2-DLPA) sodium is a phospholipid containing the medium-chain (12:0) lauric acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-168796
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Biochemical Assay Reagents
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Metabolic Disease
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1-Palmitoyl-2-13(S)-HpODE-sn-glycero-3-PC is a phospholipid that contains Palmitic acid (HY-N0830) and 13(S)-HpODE (HY-110406) at the sn-1 and sn-2 positions, respectively.
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- HY-125940S
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Isotope-Labeled Compounds
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Others
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DPPG-d62 (sodium) is deuterium labeled DPPG. DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid containing the long-chain(16:0) palmitic acid inserted at the sn-1 and sn-2 positions. DPPG sodium is used in the generation of micelles, l
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- HY-141571
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Liposome
Biochemical Assay Reagents
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Others
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DOPG sodium is a naturally occurring anionic phospholipid, containing oleic acid (18:1) inserted at the sn-1 and sn-2 positions. DOPG can form a lipid bilayer in an aqueous solution and is used in the generation of micelles, liposomes, and other artificial membranes. DOPG also exhibits anti-inflammatory properties [1].
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- HY-W339838
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14:0 Lyso PG
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Liposome
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Cancer
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1-Myristoyl-2-hydroxy-sn-glycero-3-PG sodium is a lysophospholipid containing myristic acid (14:0) at the sn-1 position. It has been used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
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- HY-168372
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Phospholipase
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Metabolic Disease
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1-Myristoyl-2-Linoleoyl-sn-glycero-3-PC is a phospholipid that contains Myristic acid (HY-N2041) and Linoleic acid (HY-N0729) at the sn-1 and sn-2 positions, respectively, which is found in human plasma [1].
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- HY-W127502
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1-Hex-GPA
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Biochemical Assay Reagents
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Others
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1-Hexadecyl lysophosphatidic acid is an ether analog of lysophosphatidic acid (LPA) containing a hexadecyl group in the sn-1 position. LPA binds to five different G protein-coupled receptors and mediates a variety of biological responses, including cell proliferation, smooth muscle contraction, platelet aggregation, neurite contraction, and cell motility.
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- HY-W343736
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1,3-DPPE; 1,3-Dipalmitoyl-sn-glycero-2-PE
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Liposome
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Cancer
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1,3-Dipalmitoyl-glycero-2-phosphoethanolamine is a phospholipid containing the saturated long-chain (16:0) stearic acid inserted at the sn-1 and sn-3 positions and PE at the sn-2 site. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-142974
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1,2-Olein-3-Docosohexaenoin; 18:1/18:1/22:6-TG; C1OO
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Endogenous Metabolite
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Metabolic Disease
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1,2-Dioleoyl-3-docosohexaenoyl-rac-glycerol is a triacylglycerol that contains oleic acid (HY-N1446) at the sn-1 and sn-2 positions and docosahexaenoic acid (HY-B2167) at the sn-3 position. It has been detected in human breast milk.
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- HY-157698
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C18(plasm)-20:4-PC; 18:0p/20:4-PC; PC(P-18:0/20:4)
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Endogenous Metabolite
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Metabolic Disease
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1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PC is a plasmalogen that contains 1(Z)-octadecenoic acid and arachidonic acid (HY-109590) at the sn-1 and sn-2 positions, respectively. It scavenges singlet oxygen in a cell-free assay.
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- HY-141614
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Phosphatidylcholine Diarachidoyl; 1,2-DAPC; L-α-Diarachidonoyl lecithin
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Liposome
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Metabolic Disease
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1,2-Diarachidoyl-sn-glycero-3-phosphocholine (1,2-DAPC) is a phospholipid containing the saturated long-chain (20:0) arachidic acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-W583869
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1-Stearoyl-2-Oleoyl-sn-glycero-3-PE; 18:0-18:1 PE; PE(18:0/18:1)
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Liposome
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Metabolic Disease
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1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine is a phospholipids that contains stearic acid and oleic acid at the sn-1 and sn-2 positions, respectively. It has been used in the generation of lipid nanoparticles (LNPs) for in vitro delivery of mRNA or nuclear-targeted plasmid DNA.
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- HY-131652
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16:0 Diether PC
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Liposome
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Metabolic Disease
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1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine (16:0 Diether PC) is a synthetic ether-linked phospholipid containing hexadecyl groups at the sn-1 and sn-2 positions. It is commonly used in the generation of liposomes and artificial membranes to study membrane dynamics.
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- HY-W800734
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MPPC; PC(14:0/16:0)
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Liposome
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Cancer
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1-Myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine (MPPC) is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a palmitic acid (16:0) at the sn-2 position. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-134174
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Liposome
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Cancer
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1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate is a phospholipid containing saturated palmitic acid (16:0) and monounsaturated oleic acid (18:1) inserted at the sn-1 and sn-2 positions, respectively. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-W710380
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1,2-Stearin-3-Olein; TG(18:0/18:0/18:1)
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Endogenous Metabolite
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Metabolic Disease
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1,2-Distearoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains stearic acid (HY-B2219) at the sn-1 and sn-2 positions and oleic acid (HY-N1446) at the sn-3 position. It has been found in cocoa butter and vegetable oils.
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- HY-115707
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16:0/0:0/18:3-DG; DG(16:0/0:0/18:3); 1-Palmitin-3-Linolenin
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Others
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Others
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1-Palmitoyl-3-linolenoyl-rac-glycerol is a diacylglycerol containing palmitic acid (HY-N0830) and α-linolenic acid (HY-N0728) at the sn-1 and sn-3 positions, respectively. It has been found in the peel and pulp of unripe Dwarf Cavendish bananas.
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- HY-145505
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18:1 Lyso-PG; 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol); 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoglycerol
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Endogenous Metabolite
Liposome
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Metabolic Disease
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1-Oleoyl-2-hydroxy-sn-glycero-3-PG (18:1 Lyso PE) sodium is a lysophospholipid containing oleic acid (18:1) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
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- HY-170634
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Biochemical Assay Reagents
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Metabolic Disease
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1-Stearoyl-2-linoleoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains Stearic acid (HY-B2219), Linoleic acid (HY-N0729), and Oleic acid (HY-N1446) at the sn-1, sn-2, and sn--3 positions, respectively.
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- HY-168390
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1-Stearin-2,3-linolein
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Endogenous Metabolite
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Others
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1,2-Stearin-3-linolein is a triacylglycerol. 1,2-Stearin-3-linolein has Stearic acid (HY-B2219) at sn-1 and sn-2 positions, and contains Linoleic acid (HY-N0729) at sn-3 position.
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- HY-168391
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Biochemical Assay Reagents
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Others
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1-Lauroyl-2-oleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol with lauric acid (HY-Y0366), oleic acid (HY-N1446), and palmitic acid (HY-N0830) at the sn-1, sn-2 and sn-3 positions, respectively [1].
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- HY-168386
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Endogenous Metabolite
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Others
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1,2-Dipalmitoyl-3-Myristoyl-rac-glycerol is a triacylglycerol in which palmitic acid (HY-N0830) is located at the sn-1 and sn-2 positions, and myristic acid (HY-N2041) is at the sn-3 position. It can be found in bovine milk fat [1].
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- HY-W704603
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1,2-Olein-3-Stearin; TG(18:1/18:1/18:0)
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Endogenous Metabolite
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Metabolic Disease
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1,2-Dioleoyl-3-stearoyl-rac-glycerol is a triacylglycerol that contains oleic acid (HY-N1446) at the sn-1 and sn-2 positions and stearic acid (HY-B2219) at the sn-3 position. It has been found in sunflower, corn, and soybean oils, as well as ostrich oil.
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- HY-W339206
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Endogenous Metabolite
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Others
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1,2-Dinonanoyl-sn-glycero-3-phosphocholine, a specific phosphatidylcholine, features fatty acyl configurations that can influence the physical properties of membranes, making it a key component for generating eicosanoids. As a phospholipid abundant in membranes, it has fatty acids attached to glycerol at the sn-1 and sn-2 positions via ester bonds.
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- HY-149549
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Biochemical Assay Reagents
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Others
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1-Stearoyl-3-Oleoyl-rac-glycerol (Compound 2) is a diacylglycerol with a stearic acid and an oleic acid at sn-1 and sn-3 position. 1-Stearoyl-3-Oleoyl-rac-glycerol can be used as the food additive, such as the substitute for cocoa butter, the ingredient in shortening, or candy coating [1].
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- HY-W339816
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Others
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Others
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(S,R)-Bis(monomyristoylglycero)phosphate ammonium actively contributes to cargo sorting by promoting the degradation and sorting of lipids, and it plays a critical role in the sorting of polyunsaturated fatty acids (PUFAs) within acidic organelles. This phospholipid features two phosphate-linked glycerol molecules arranged in a unique sn-1 glycerophospho-sn-1′ glycerol stereoconformation, with each glycerol molecule esterified to a myristic acid. Typically, it is found in the intraluminal vesicles (ILVs) of late endosomes and lysosomes.
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- HY-145522
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MEM; 1,3-Myristin-2-Eicosapentaenoin; 14:0/20:5/14:0-TG
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Biochemical Assay Reagents
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Metabolic Disease
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1,3-Dimyristoyl-2-eicosapentaenoyl glycerol (MEM) is a triacylglycerol that contains myristic acid (HY-N2041) at the sn-1 and sn-3 positions and eicosapentaenoic acid at the sn-2 position. The myristoyl groups in MEM do not affect the oxidative stability of eicosapentaenoic acid (EPA) during long-term storage at 25°C.
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- HY-W706672
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Glycerol Tritricosanoate; TG(23:0/23:0/23:0); Tritricosanoin
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Endogenous Metabolite
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Metabolic Disease
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1,2,3-Tritricosanoyl glycerol is a triacylglycerol that contains tricosanoic acid (HY-W009081) at the sn-1, sn-2, and sn-3 positions. It has been used as an internal standard for the quantification of fatty acids in the triglyceride component of human aortic endothelial cells (HAECs) grown in media supplemented with stearic and/or oleic acid.
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- HY-115706
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1,3-Ditetracosanoin
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Biochemical Assay Reagents
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Neurological Disease
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13-Dilignoceroyl glycerol is a diacylglycerol containing lignoceric acid (HY-121883 ) at the sn-1 and sn-3 positions. Lignoceric acid is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro-hepato-renal syndrome and adrenoleukodystrophy research [1] .
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- HY-W778471
-
DG(18:2/0:0/18:3); 1-Linolein-3-α-Linolenin; 1-Linolein-3-Linolenin
|
Endogenous Metabolite
|
Metabolic Disease
|
1-Linoleoyl-3-α-linolenoyl-rac-glycerol is a diacylglycerol that contains linoleic acid (HY-N0729) at the sn-1 position and α-linolenic acid (HY-N0728) at the sn-3 position. It has been found in olive oil subjected to lipase-catalyzed glycerolysis with immobilized lipase B from C. antarctica.
|
-
- HY-145506
-
18:0 Lyso PG sodium
|
Liposome
|
Metabolic Disease
|
1-Stearoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (18:0 Lyso PE) sodium is a lysophospholipid containing stearic acid (18:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
|
-
- HY-145507
-
1-Palmitoyl-2-hydroxy-sn-glycero-3-PG sodium; 16:0 Lyso PG; PG(16:0/0:0); 1-Hexadecanoyl-sn-glycero-3-phospho-(1'racglycerol) (sodium)
|
Liposome
|
Metabolic Disease
|
1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (16:0 Lyso PE) sodium is a lysophospholipid containing palmitic acid (16:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
|
-
- HY-W704597
-
1-Palmitin-2-Olein-3-Stearin; TG(16:0/18:1/18:0)
|
Endogenous Metabolite
|
Metabolic Disease
|
1-Palmitoyl-2-oleoyl-3-stearoyl-rac-glycerol is a triacylglycerol that contains palmitic acid (HY-N0830) at the sn-1 position, oleic acid (HY-N1446) at the sn-2 position, and stearic acid (HY-B2219) at the sn-3 position. It is one of the primary triacylglycerols found in cocoa butter.
|
-
- HY-169036
-
-
- HY-142971
-
1-Myristin-2-Linolein-3-Olein; TG(14:0/18:2/18:1)
|
Endogenous Metabolite
|
Metabolic Disease
|
1-Myristoyl-2-linoleoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains myristic acid (HY-N2041), linoleic acid (HY-N0729), and oleic acid (HY-N1446) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in mature human milk, infant formula fats, and butterfat.
|
-
- HY-170623
-
|
Biochemical Assay Reagents
|
Metabolic Disease
|
1-Palmitoyl-2-stearoyl-3-butyryl-rac-glycerol is a triacylglycerol containing Palmitic acid (HY-N0830), Stearic acid (HY-B2219), and Butyric acid (HY-B0350) at the sn-1, sn-2, and sn-3 positions, respectively. It has been used to determine the stereospecificity and typoselectivity of lipases.1
|
-
- HY-W643167
-
Glycerol Tritridecanoyl; 13:0 TAG; 13:0/13:0/13:0-TG
|
Biochemical Assay Reagents
|
Infection
|
1,2,3-Tritridecanoyl glycerol is a synthetic triacylglycerol that contains tridecanoic acid in the sn-1, sn-2, and sn-3 positions. It has been used as a standard for the relative quantification of triacylglycerols in C. elegans fat stores. It has also been used as an internal standard for the quantification of triacylglycerols in the serum and liver of adult rat offspring receiving dietary conjugated linoleic acids during and after gestation.
|
-
- HY-157697
-
18:0p/20:4-PE; C18(Plasm)-20:4-PE; PE(P-18:0/20:4)
|
Endogenous Metabolite
|
Metabolic Disease
|
1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PE (18:0p/20:4-PE; C18(Plasm)-20:4-PE) is a plasmalogen that contains 1(Z)-octadecenoic acid and arachidonic acid (HY-109590) at the sn-1 and sn-2 positions, respectively.
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-
- HY-125940
-
|
Liposome
|
Others
|
DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid that contains long-chain (16:0) palmitic acid inserted at the sn-1 and sn-2 positions, and it serves as an active component to prevent BaP molecules from entering the water subphase. DPPG sodium is used to prepare micelles, liposomes, and other types of artificial membranes that can resist damage from UV radiation [1] .
|
-
- HY-W127386
-
3-Dodecyloxypropane-1,2-diol
|
Biochemical Assay Reagents
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Others
|
1-O-Dodecyl-rac-glycerol is a class of organic compounds belonging to the class of racemic glycerol derivatives. It consists of a dodecyl chain attached to the sn-1 position of the racemic glycerol molecule. 1-O-Dodecyl-rac-glycerol has various applications in the pharmaceutical industry, especially as an intermediate in the synthesis of lipid drug delivery systems and membranes. Additionally, it has potential use as an emulsifier and surfactant in cosmetic and personal care products.
|
-
- HY-W710399
-
DG(16:0/0:0/18:0); 1-Palmitin-3-Stearin
|
Endogenous Metabolite
|
Metabolic Disease
|
1-Palmitoyl-3-stearoyl-rac-glycerol is a diacylglycerol that contains palmitic acid (HY-N0830) at the sn-1 position and stearic acid (HY-B2219) at the sn-3 position. It has been found in palm-based diacylglycerols produced from palm stearin, palm mid fraction, palm oil, and palm olein, as well as in wheat bran and brewer’s spent grain extracts.
|
-
- HY-W710440
-
1,2-Stearin-3-palmitin; TG(18:0/18:0/16:0)
|
Endogenous Metabolite
|
Others
|
1,2-Distearoyl-3-palmitoyl-rac-glycerol is a triglyceride found in cocoa butter, lard, and cod liver oil. 1,2-Distearoyl-3-palmitoyl-rac-glycerol is formed by combining the glycerol skeleton with Stearic acid (HY-B2219) (sn-1 and sn-2 positions) and Palmitic acid (sn-3 positions) (HY-N0830) [1] .
|
-
- HY-168780
-
|
Endogenous Metabolite
|
Others
|
1-Palmitoyl-2-arachidoyl-3-oleoyl-rac-glycerol is a triacylglycerol. 1-Palmitoyl-2-arachidoyl-3-oleoyl-rac-glycerol contains Palmitic acid (HY-N0830), Arachidonic acid (HY-109590), and Oleic acid (HY-N1446) at sn-1, sn-2, and sn-3 locations, respectively [1].
|
-
- HY-W127408
-
|
Biochemical Assay Reagents
Endogenous Metabolite
|
Others
|
1,2,3-Tripalmitoleoyl-rac-glycerol is a triacylglycerol containing palmitoleic acid at the sn-1, sn-2 and sn-3 positions. It reduces erythrocyte deformability in a concentration-dependent manner in the Reid filtration assay. Hepatic levels of 1,2,3-tripalmitoleoyl-rac-glycerol are increased in a JAK2L mouse model of hepatic steatosis. 1,2,3-Tripalmitoleoyl-rac-glycerol plasma levels are reduced in patients with predialysis renal disease.
|
-
- HY-117168
-
|
Endogenous Metabolite
|
Metabolic Disease
|
1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (HY-N0729) (18:2) side chains attached at both the sn-1 and sn-2 positions. It has been found as a component of phosphatidic acid in rat liver mitochondria and in spinach chloroplast membranes. 1,2-Dilinoleoyl-sn-glycerol is upregulated in some pregnant women and has been used as a biomarker to predict later preeclampsia in early pregnancy.
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-
- HY-145545
-
PE(18:0/22:4); 1-Stearoyl-2-Docosatraenoyl-sn-glycero-3-PE
|
Endogenous Metabolite
|
Metabolic Disease
|
1-Stearoyl-2-adrenoyl-sn-glycero-3-PE is a phospholipid that contains stearic acid (HY-B2219) and adrenic acid (HY-W013215) at the sn-1 and sn-2 positions, respectively. 1-Stearoyl-2-adrenoyl-sn-glycero-3-PE levels are inversely correlated with subject age in mitochondria isolated from human post-mortem hippocampus.
|
-
- HY-W699318
-
|
Reactive Oxygen Species
|
Others
|
1-Oleoyl-2-palmitoylglycerol is a diacylglycerol in which an oleic acid and a palmitic acid are attached to sn-1 and sn-2 position. 1-Oleoyl-2-palmitoylglycerol enhances the inhibition of superoxide anion production induced by fMLF/cytochalasin B (CB) in human neutrophils. 1-Oleoyl-2-palmitoylglycerol can be used in research about lipid metabolism, membrane fluidity, or the distribution and function of lipids in cells [1] .
|
-
- HY-W010667
-
1,3-Dipalmitoyl-2-oleoylglycerol; ?1,3-Palmitin-2-Olein; TG(16:0/18:1/16:0)
|
Endogenous Metabolite
|
Metabolic Disease
|
1,3-Dipalmitoyl-2-oleoyl glycerol (1,3-Palmitin-2-Olein; TG(16:0/18:1/16:0)) is a triacylglycerol that contains palmitic acid (HY-N0830) at the sn-1 and sn-3 positions and oleic acid (HY-N1446) at the sn-2 position. It has been found in cocoa butter, Chinese tallow butter, and the palm stearin fraction of palm oil.
|
-
- HY-141636
-
1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine; PAPC; PC(16:0/20:4)
|
Endogenous Metabolite
Biochemical Assay Reagents
|
Cardiovascular Disease
|
1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid containing palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively, that is found in biological membranes. PAPC is oxidized in vivo, and its oxidation products are involved in chronic inflammation and vascular disease. PAPC has been used to study signaling of oxidized phospholipids. Levels of PAPC are decreased in isolated human multiple myeloma cells.
|
-
- HY-168394
-
1,2-Palmitin-3-stearin
|
Endogenous Metabolite
|
Others
|
1,2-Dipalmitoyl-3-stearoyl-rac-glycerol (1,2-Palmitin-3-stearin) is a triacylglycerol found in ostrich and emu oils as well as cow milk fat. The sn-1 and sn-2 positions of 1,2-Dipalmitoyl-3-stearoyl-rac-glycerol contain palmitic acid (HY-N0830), and the sn-3 position contains stearic acid (HY-B2219) [1] .
|
-
- HY-168393
-
1,3-Palmitin-2-stearin
|
Endogenous Metabolite
|
Metabolic Disease
|
1,3-Dipalmitoyl-2-stearoyl glycerol (1,3-Palmitin-2-stearin) is a triacylglycerol in which palmitic acid (HY-N0830) is located at the sn-1 and sn-3 positions, and stearic acid (HY-B2219) is at the sn-2 position. The levels of 1,3-Dipalmitoyl-2-stearoyl glycerol are associated with energy depletion caused by reduced food intake in rats [1].
|
-
- HY-118442
-
Tetradecasphing-4-enine
|
PKC
|
Cancer
|
Sphingosine (d14:1) (Tetradecasphing-4-enine), a sphingolipid, is a potent Protein kinase C (PKC) inhibitor. Sphingosine (d14:1) prevents its interaction with sn-1,2-diacylglycerol (DAG)/Phorbol esters [1].
|
-
- HY-W706672R
-
|
Endogenous Metabolite
|
Metabolic Disease
|
Propane-1,2,3-triyl tritricosanoate (Standard) is the analytical standard of Propane-1,2,3-triyl tritricosanoate. This product is intended for research and analytical applications. 1,2,3-Tritricosanoyl glycerol is a triacylglycerol that contains tricosanoic acid (HY-W009081) at the sn-1, sn-2, and sn-3 positions. It has been used as an internal standard for the quantification of fatty acids in the triglyceride component of human aortic endothelial cells (HAECs) grown in media supplemented with stearic and/or oleic acid.
|
-
- HY-W339834
-
|
Acyltransferase
Endogenous Metabolite
Liposome
|
Others
|
1-Stearoyl-sn-glycerol 3-phosphate sodium is a bioactive phospholipid that plays a crucial role in modulating cellular processes such as motility, proliferation, invasion, survival, and growth factor production, primarily through its interaction with G protein-coupled receptors (GPCRs). Typically found at low concentrations in plasma (~100nM), this compound is synthesized during the formation of membrane phospholipids and is derived from various cell types, including activated platelets, epithelial cells, leukocytes, neuronal cells, and tumor cells. Its unique structure includes stearic acid at the sn-1 position alongside a hydroxyl group at the sn-2 position.
|
-
- HY-W923483
-
1-O-Hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine
|
Platelet-activating Factor Receptor (PAFR)
Endogenous Metabolite
|
Cardiovascular Disease
|
C16-18:1 PC (1-O-Hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine), also known as 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine (HOPC), is a member of the platelet-activating factor (PAF) family of glycerophospholipids and serves as a pro-inflammatory lipid mediator with diverse biological and pharmacological effects; it features a mono-ether structure with an oleoyl chain (18:1) ester-linked at the sn-2 position and a hexadecyl chain (16:0) ether-linked at the sn-1 position.
|
-
- HY-145540
-
1,2-Palmitin-3-caprylin
|
Biochemical Assay Reagents
|
Metabolic Disease
|
1,2-Dipalmitoyl-3-Octanoyl-rac-glycerol is a triacylglycerol containing palmitic acid (HY-N0830) at the sn-1 and sn-2 positions and octanoic acid (HY-41417) at the sn-3 position. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. Octanoic acid is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes. Octanoic acid is also a tremor-suppressing agent [1] .
|
-
- HY-168371
-
|
Scavenger Receptor Class B type I (SR-BI)
|
Metabolic Disease
|
1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC (13-HODE-PC) is an oxidized phospholipid that contains Palmitic acid (HY-N0830) and 13(S)-HODE (HY-113884B) at the sn-1 and sn-2 positions, respectively. 1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC has the ability to compete for the binding of 125I-NO2-LDL (5 g/mL) to CD36-transfected 293 cells, with the IC50 of > 200 μM [1].
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-
- HY-W127357
-
|
Biochemical Assay Reagents
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Others
|
Glyceryl trinonanoate is a triacylglycerol containing nonanoic acid at the sn-1, sn-2 and sn-3 positions. It has been found in Schizochytrium biomass. 1 1,2,3-Trinonanoyl-rac-glycerol increases blood levels of the ketone body D-(-)-3-hydroxybutyrate in neonatal rhesus monkeys. 2|1. Mioso, R., Toledo Marante, FJ, González, JE, et al. Schizochytrium sp. metabolite analysis. Oleaginous microbial sources of biodiesel by GC-MS. braz. J. Microbiology. 45(2), 403-409 (2014).|2. Tetrick, MA, Greer, FR and Benevenga, NJ Blood D- ( )-3-Hydroxybutyric acid concentration. Compare. medicine. 60(6), 486-490 (2010).
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-
- HY-145504
-
1,2-Palmitin-3-Linoelaidin
|
Biochemical Assay Reagents
|
Metabolic Disease
|
12-Dipalmitoyl-3-Linoelaidoyl-rac-glycerol is a triacylglycerol containing palmitic acid (HY-N0830) at the sn-1 and sn-2 positions and linoelaidic acid (HY-W071746) at the sn-3 position. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. Linolelaidic acid, an omega-6 trans fatty acid, acts as a source of energy. Linolelaidic acid is an essential nutrient, adding in enteral, parenteral, and infant formulas. Linolelaidic acid can be used for heart diseases research [1] .
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-
- HY-145473
-
15(S)-HETE-SAPE; 15(S)-Hydroxyeicosatetraenoic acid-SAPE; 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-Phosphatidylethanolamine
|
Endogenous Metabolite
|
Metabolic Disease
|
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE (15(S)-HETE-SAPE) is a phospholipid containing stearic acid (HY-B2219) at the sn-1 position and 15(S)-HETE (HY-113336) at the sn-2 position. 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is formed by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE) by 15-LOX in human peripheral mononuclear cells activated with the calcium ionophore A23187 (HY-N6687).
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-
- HY-156041
-
Lyso-PE (egg); LPE (egg); L-α-lysophosphatidylethanolamine
|
Endogenous Metabolite
|
Metabolic Disease
|
Lysophosphatidylethanolamine (LPE) is a naturally-occurring lysophospholipid that can be generated via deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). It increases the phosphorylation of ERK1/2 in PC12 cells, an effect that can be blocked by the MEK inhibitors U-0126 (HY-12031A) and PD 98059 (HY-12028) and the EGFR inhibitor AG-1478 (HY-13524).1 LPE also increases neurite outgrowth and expression of neurofilament M in PC12 cells. LPE inhibits the activity of phospholipase D (PLD) partially purified from cabbage.3 This product contains lysophosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 position and a hydroxy group at the sn-2 position.
|
-
- HY-112747
-
LPI; PE (soy)
|
Phospholipase
|
Infection
|
Phosphatidylethanolamine is the most abundant phospholipid in prokaryotes and the second most abundant found in the membrane of mammalian, plant, and yeast cells, comprising approximately 25% of total mammalian phospholipids. In the brain, phosphatidylethanolamine comprises almost half of the total phospholipids. It is synthesized mainly through the cytidine diphosphate-ethanolamine and phosphatidylserine decarboxylation pathways, which occur in the endoplasmic reticulum (ER) and mitochondrial membranes, respectively. It is a precursor in the synthesis of phosphatidylcholine and arachidonoyl ethanolamide and is a source of ethanolamine used in various cellular functions. In E. coli, phosphatidylethanolamine deficiency prevents proper assembly of lactose permease, suggesting a role as a lipid chaperone. It is a cofactor in the propagation of prions in vitro and can convert recombinant mammalian proteins into infectious molecules even in the absence of RNA. This product contains phosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 and sn-2 positions.
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-
- HY-115701
-
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-phosphoethanolamine; 15(S)-HpETE-SAPE; 15(S)-hydroperoxyeicostetraenoic acid-SAPE
|
Others
|
Inflammation/Immunology
|
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-Pe (SAPE) by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.
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-
- HY-141636S
-
1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d9-1; PAPC-d9-1; PC(16:0/20:4)-d9-1
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cardiovascular Disease
|
1-PalMitoyl-2-arachidoyllecithin-d9-1 (1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d9-1) is deuterium labeled 1-PalMitoyl-2-arachidoyllecithin. 1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid containing palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively, that is found in biological membranes. PAPC is oxidized in vivo, and its oxidation products are involved in chronic inflammation and vascular disease. PAPC has been used to study signaling of oxidized phospholipids. Levels of PAPC are decreased in isolated human multiple myeloma cells [1].
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-
- HY-W127391
-
(Rac)-1,2-Didodecanoylglycerol
|
Biochemical Assay Reagents
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Others
|
1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981).
|
-
- HY-W010736A
-
|
Biochemical Assay Reagents
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Others
|
1,2-Dipalmitoyl-rac-glycerol is a diacylglycerol containing palmitic acid at the sn-1 and sn-2 positions (Cat. No. 10006627). It is found in a variety of vegetable oils, including palm, soybean, canola, and corn. 1 \n 1,2-Dipalmitoyl-rac-glycerol MaxSpec Standard is a quantitative grade standard of 1,2-dipalmitoyl-rac-glycerol prepared for mass spectrometry and related applications requiring quantitative reproducibility . The solution has been prepared gravimetrically and contained in argon-sealed deactivated glass ampoules. Concentrations were verified by comparison to independently prepared calibration standards. This 1,2-dipalmitoyl-rac-glycerol MaxSpec Standard is guaranteed to meet specifications for identity, purity, stability, and concentration and is supplied with a batch-specific Certificate of Analysis. Ongoing stability testing is performed to ensure concentrations remain accurate throughout the shelf life of the product. Note: Add more solution to the vial than listed. Therefore, accurate volume measurements are necessary to prepare calibration standards. Follow recommended storage and handling conditions to maintain product quality.
|
-
- HY-145473S
-
15(S)-HETE-SAPE; 15(S)-Hydroxyeicosatetraenoic acid-SAPE-d11; 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-Phosphatidylethanolamine-d11
|
Isotope-Labeled Compounds
Others
|
Metabolic Disease
|
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 (15(S)-HETE-SAPE-d11) is deuterium labeled 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE. 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HETE at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 (HY-N6687) by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE) by 15-LO. Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes [1].
|
-
- HY-W251428
-
Egg PG
|
Biochemical Assay Reagents
|
Others
|
Phosphatidylglycerol is a naturally occurring anionic phospholipid that is a component of plant, animal and bacterial cell membranes. It is present in prokaryotes and eukaryotes less than phosphatidylethanolamine, and in eukaryotes less than phosphatidylcholine. It is formed by the reaction between CDP-diglyceride and L-α-glycerol 3-phosphate followed by dephosphorylation and is the metabolic precursor of cardiolipin. Phosphatidylglycerols containing polyunsaturated and monounsaturated fatty acyl chains inhibit and promote the proliferation of murine keratinocytes, respectively. Phosphatidylglycerol is the second-largest lipid component of mammalian lung surfactant, accounting for 10% of lipids, and has reduced levels of pulmonary surfactant in infants with respiratory distress syndrome. Phosphatidylglycerol (egg) is a mixture of phosphatidylglycerols isolated from eggs with various fatty acyl groups at the sn-1 and sn-2 positions. References: [1]. Ohtsuka, T., Nishijima, M., and Akamatsu, Y. Phosphatidylglycerol phosphate synthase-deficient somatic mutants with impaired phosphatidylglycerol and cardiolipin biosynthesis J. Biol. Chemical. 268(30), 22908-22913 (1993).[2]. Furse, S. Are phosphatidylglycerols essential for terrestrial life J. Chemistry. biology. 10(1), 1-9 (2016).[3]. Xie, D., Seremwe, M., Edwards, JG, et al. Different effects of different phosphatidylglycerols on the proliferation of mouse keratinocytes PLoS One 9(9), e107119 (2014).
|
-
- HY-124314
-
|
DAGL
MAGL
|
Metabolic Disease
|
LEI-106 is a potent, dual sn-1-Diacylglycerol lipase α (DAGL-α)/ABHD6 inhibitor with an IC50 of 18 nM for DAGL-α and a Ki of 0.8 μM for ABHD6. LEI-106 inhibits the hydrolysis of [ 14C]-sn-1-oleoyl-2-arachidonoyl-glycerol, the natural substrate of DAGL-α, with a Ki of 0.7 μM [1].
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-
Cat. No. |
Product Name |
Type |
-
- HY-141572
-
sn-1,2-Dioleoylglycerol
|
Drug Delivery
|
ALN29882 is a glycerolipid located on the plasma membrane. It consists of two fatty acid chains covalently linked to a single glycerol molecule by means of an ester bond. 18:1 DG has been used as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay. It is also used as a substrate in the DGAT-1 enzyme assay to evaluate compounds as potential inhibitors of DGAT-1. Suitable for lipoprotein overlay screening assays with the recombinant protein His-AtROP6.
|
-
- HY-141571
-
|
Drug Delivery
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DOPG sodium is a naturally occurring anionic phospholipid, containing oleic acid (18:1) inserted at the sn-1 and sn-2 positions. DOPG can form a lipid bilayer in an aqueous solution and is used in the generation of micelles, liposomes, and other artificial membranes. DOPG also exhibits anti-inflammatory properties [1].
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- HY-W127502
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1-Hex-GPA
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Cell Assay Reagents
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1-Hexadecyl lysophosphatidic acid is an ether analog of lysophosphatidic acid (LPA) containing a hexadecyl group in the sn-1 position. LPA binds to five different G protein-coupled receptors and mediates a variety of biological responses, including cell proliferation, smooth muscle contraction, platelet aggregation, neurite contraction, and cell motility.
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- HY-125940
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Drug Delivery
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DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid that contains long-chain (16:0) palmitic acid inserted at the sn-1 and sn-2 positions, and it serves as an active component to prevent BaP molecules from entering the water subphase. DPPG sodium is used to prepare micelles, liposomes, and other types of artificial membranes that can resist damage from UV radiation [1] .
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- HY-W127391
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(Rac)-1,2-Didodecanoylglycerol
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Drug Delivery
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1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981).
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- HY-W251428
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Egg PG
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Drug Delivery
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Phosphatidylglycerol is a naturally occurring anionic phospholipid that is a component of plant, animal and bacterial cell membranes. It is present in prokaryotes and eukaryotes less than phosphatidylethanolamine, and in eukaryotes less than phosphatidylcholine. It is formed by the reaction between CDP-diglyceride and L-α-glycerol 3-phosphate followed by dephosphorylation and is the metabolic precursor of cardiolipin. Phosphatidylglycerols containing polyunsaturated and monounsaturated fatty acyl chains inhibit and promote the proliferation of murine keratinocytes, respectively. Phosphatidylglycerol is the second-largest lipid component of mammalian lung surfactant, accounting for 10% of lipids, and has reduced levels of pulmonary surfactant in infants with respiratory distress syndrome. Phosphatidylglycerol (egg) is a mixture of phosphatidylglycerols isolated from eggs with various fatty acyl groups at the sn-1 and sn-2 positions. References: [1]. Ohtsuka, T., Nishijima, M., and Akamatsu, Y. Phosphatidylglycerol phosphate synthase-deficient somatic mutants with impaired phosphatidylglycerol and cardiolipin biosynthesis J. Biol. Chemical. 268(30), 22908-22913 (1993).[2]. Furse, S. Are phosphatidylglycerols essential for terrestrial life J. Chemistry. biology. 10(1), 1-9 (2016).[3]. Xie, D., Seremwe, M., Edwards, JG, et al. Different effects of different phosphatidylglycerols on the proliferation of mouse keratinocytes PLoS One 9(9), e107119 (2014).
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- HY-W127386
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3-Dodecyloxypropane-1,2-diol
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Drug Delivery
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1-O-Dodecyl-rac-glycerol is a class of organic compounds belonging to the class of racemic glycerol derivatives. It consists of a dodecyl chain attached to the sn-1 position of the racemic glycerol molecule. 1-O-Dodecyl-rac-glycerol has various applications in the pharmaceutical industry, especially as an intermediate in the synthesis of lipid drug delivery systems and membranes. Additionally, it has potential use as an emulsifier and surfactant in cosmetic and personal care products.
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- HY-W127408
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Drug Delivery
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1,2,3-Tripalmitoleoyl-rac-glycerol is a triacylglycerol containing palmitoleic acid at the sn-1, sn-2 and sn-3 positions. It reduces erythrocyte deformability in a concentration-dependent manner in the Reid filtration assay. Hepatic levels of 1,2,3-tripalmitoleoyl-rac-glycerol are increased in a JAK2L mouse model of hepatic steatosis. 1,2,3-Tripalmitoleoyl-rac-glycerol plasma levels are reduced in patients with predialysis renal disease.
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- HY-W127357
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Drug Delivery
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Glyceryl trinonanoate is a triacylglycerol containing nonanoic acid at the sn-1, sn-2 and sn-3 positions. It has been found in Schizochytrium biomass. 1 1,2,3-Trinonanoyl-rac-glycerol increases blood levels of the ketone body D-(-)-3-hydroxybutyrate in neonatal rhesus monkeys. 2|1. Mioso, R., Toledo Marante, FJ, González, JE, et al. Schizochytrium sp. metabolite analysis. Oleaginous microbial sources of biodiesel by GC-MS. braz. J. Microbiology. 45(2), 403-409 (2014).|2. Tetrick, MA, Greer, FR and Benevenga, NJ Blood D- ( )-3-Hydroxybutyric acid concentration. Compare. medicine. 60(6), 486-490 (2010).
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- HY-W010736A
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Biochemical Assay Reagents
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1,2-Dipalmitoyl-rac-glycerol is a diacylglycerol containing palmitic acid at the sn-1 and sn-2 positions (Cat. No. 10006627). It is found in a variety of vegetable oils, including palm, soybean, canola, and corn. 1 \n 1,2-Dipalmitoyl-rac-glycerol MaxSpec Standard is a quantitative grade standard of 1,2-dipalmitoyl-rac-glycerol prepared for mass spectrometry and related applications requiring quantitative reproducibility . The solution has been prepared gravimetrically and contained in argon-sealed deactivated glass ampoules. Concentrations were verified by comparison to independently prepared calibration standards. This 1,2-dipalmitoyl-rac-glycerol MaxSpec Standard is guaranteed to meet specifications for identity, purity, stability, and concentration and is supplied with a batch-specific Certificate of Analysis. Ongoing stability testing is performed to ensure concentrations remain accurate throughout the shelf life of the product. Note: Add more solution to the vial than listed. Therefore, accurate volume measurements are necessary to prepare calibration standards. Follow recommended storage and handling conditions to maintain product quality.
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Product Name |
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Research Area |
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-138815S
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(S)-N-(1H-Indole-3-acetyl)tryptophan-d4 is deuterium labeled (S)-N-(1H-Indole-3-acetyl)tryptophan. (S)-N-(1H-Indole-3-acetyl)tryptophan (compound 4a) is a Tryptophan derivative that weakly inhibits β-D-glucosidase [1] .
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- HY-125940S
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DPPG-d62 (sodium) is deuterium labeled DPPG. DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid containing the long-chain(16:0) palmitic acid inserted at the sn-1 and sn-2 positions. DPPG sodium is used in the generation of micelles, l
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- HY-141636S
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1-PalMitoyl-2-arachidoyllecithin-d9-1 (1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d9-1) is deuterium labeled 1-PalMitoyl-2-arachidoyllecithin. 1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid containing palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively, that is found in biological membranes. PAPC is oxidized in vivo, and its oxidation products are involved in chronic inflammation and vascular disease. PAPC has been used to study signaling of oxidized phospholipids. Levels of PAPC are decreased in isolated human multiple myeloma cells [1].
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- HY-145473S
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1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 (15(S)-HETE-SAPE-d11) is deuterium labeled 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE. 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HETE at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 (HY-N6687) by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE) by 15-LO. Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes [1].
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Cat. No. |
Product Name |
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Classification |
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- HY-W440981
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1-Stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine
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Phospholipids
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SPPC is a phospholipid with different length of fatty acid. The sn-1 position contains a stearic acid (18:0) while the sn-2 position is occupied by a palmitic acid (16:0).
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- HY-W019833
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PC(14:0/18:0); 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine
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Phospholipids
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MSPC is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a stearic acid (18:0) at the sn-2 position. It can self assemble in water to form lipid bilayers. Reagent grade, for research purpose.
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- HY-W440982
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PC(18:0/18:1); 2-?Oleoyl-?1-?stearoyl-?sn-?glycero-?3-?phosphocholine
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Phospholipids
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SOPC is an asymmetrical phospholipid with saturated fatty acid (stearic acid/18:0) at sn-1 position and unsaturated fatty acid (oleic acid/18:1) at sn-2 position. SOPC can be used for various biochemical studies [1].
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- HY-W040185
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1,2-DPPA sodium; PA(14:0/14:0) sodium; 1,2-Dimyristoyl-sn-glycero-3-phosphate sodium
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Phospholipids
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1,2-Dimyristoyl-sn-glycero-3-phosphate monosodium is a phospholipid containing the long-chain (14:0) myristic acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-W440957
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PC(16:0/14:0); 1-palmitoyl-2-myristoyl-sn-glycero-3-phosphocholine
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Phospholipids
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PMPC is a phosphatidylcholine with asymmetrical fatty acid. Palmitic acid occupies sn-1 position while myristic acid is placed at the sn-2 position.
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- HY-W800733
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1,2-Dilauroyl-sn-glycero-3-phosphorylglycerol; PG(12:0/12:0)
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Phospholipids
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DLPG is a phospholipid containing lauric acid (12 chain fatty acid) inserted at the sn-1 and sn-2 positions. Its phosphate group is attached to glycerol. It is used in the generation of micelles, liposomes, and other artificial membranes.
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- HY-W440958
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PSPC; PC(16:0-18:0)
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Phospholipids
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1-Palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine is an assymetrical phospholipid containing saturated palmitic and stearic acid at the sn-1 and sn-2 position respectively. The phosphate group is attached to choline.
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- HY-W590536
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1-Palmitoyl-2-Lauroyl-sn-glycero-3-Phosphatidylcholine; 1-Palmitoyl-2-Lauroyl-sn-glycero-3-Phosphocholine
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Phospholipids
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1,2-PLPC is a phospholipid containing palmitoyl (16:0) and lauryl (12:0) acyl substituents at the sn-1 and sn-2 positions, respectively. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-W725327
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1,2-Dipropionyl-sn-glycero-3-Phosphatidylcholine; 1,2-Dipropionyl-sn-glycero-3-Phosphocholine; PC(3:0/3:0)
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Phospholipids
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1,2-Dipropionyl-sn-glycero-3-PC is a phospholipid containing propionic acid at the sn-1 and sn-2 positions. It has been used to study the interaction between water and the phosphocholine headgroup in aqueous solutions.
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- HY-157672
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Phospholipids
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18:1-14:0 PC, an asymmetric phospholipid featuring an unsaturated acyl chain in the sn-1 position, can create a hydrophobic surface in mucus by functioning as a surfactant to impede bacterial penetrance, while also serving as a dietary source of choline.
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- HY-157618
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Phospholipids
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18:0-18:1 PG sodium is a hydrogenated phospholipid that contributes to the stability of photosystem I and II protein complexes and plays a role in bacterial defense mechanisms, featuring two extra methylene groups in its saturated sn-1 chain, and is present in the thylakoid membranes of higher plants and cyanobacteria.
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- HY-W800805
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Phospholipids
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DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.
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- HY-113925
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1,2-DLPA Sodium; (2R)-2,3-bis(dodecanoyloxy)propyl hydrogen phosphate sodium
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Phospholipids
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1,2-Dilauroyl-sn-glycero-3-phosphate (1,2-DLPA) sodium is a phospholipid containing the medium-chain (12:0) lauric acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-141571
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Phospholipids
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DOPG sodium is a naturally occurring anionic phospholipid, containing oleic acid (18:1) inserted at the sn-1 and sn-2 positions. DOPG can form a lipid bilayer in an aqueous solution and is used in the generation of micelles, liposomes, and other artificial membranes. DOPG also exhibits anti-inflammatory properties [1].
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- HY-W339838
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14:0 Lyso PG
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Phospholipids
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1-Myristoyl-2-hydroxy-sn-glycero-3-PG sodium is a lysophospholipid containing myristic acid (14:0) at the sn-1 position. It has been used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
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- HY-W343736
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1,3-DPPE; 1,3-Dipalmitoyl-sn-glycero-2-PE
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Phospholipids
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1,3-Dipalmitoyl-glycero-2-phosphoethanolamine is a phospholipid containing the saturated long-chain (16:0) stearic acid inserted at the sn-1 and sn-3 positions and PE at the sn-2 site. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-157698
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C18(plasm)-20:4-PC; 18:0p/20:4-PC; PC(P-18:0/20:4)
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Phospholipids
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1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PC is a plasmalogen that contains 1(Z)-octadecenoic acid and arachidonic acid (HY-109590) at the sn-1 and sn-2 positions, respectively. It scavenges singlet oxygen in a cell-free assay.
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- HY-141614
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Phosphatidylcholine Diarachidoyl; 1,2-DAPC; L-α-Diarachidonoyl lecithin
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Phospholipids
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1,2-Diarachidoyl-sn-glycero-3-phosphocholine (1,2-DAPC) is a phospholipid containing the saturated long-chain (20:0) arachidic acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-W583869
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1-Stearoyl-2-Oleoyl-sn-glycero-3-PE; 18:0-18:1 PE; PE(18:0/18:1)
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Phospholipids
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1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine is a phospholipids that contains stearic acid and oleic acid at the sn-1 and sn-2 positions, respectively. It has been used in the generation of lipid nanoparticles (LNPs) for in vitro delivery of mRNA or nuclear-targeted plasmid DNA.
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- HY-131652
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16:0 Diether PC
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Phospholipids
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1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine (16:0 Diether PC) is a synthetic ether-linked phospholipid containing hexadecyl groups at the sn-1 and sn-2 positions. It is commonly used in the generation of liposomes and artificial membranes to study membrane dynamics.
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- HY-W800734
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MPPC; PC(14:0/16:0)
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Phospholipids
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1-Myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine (MPPC) is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a palmitic acid (16:0) at the sn-2 position. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-134174
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Phospholipids
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1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate is a phospholipid containing saturated palmitic acid (16:0) and monounsaturated oleic acid (18:1) inserted at the sn-1 and sn-2 positions, respectively. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-145505
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18:1 Lyso-PG; 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol); 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoglycerol
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Phospholipids
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1-Oleoyl-2-hydroxy-sn-glycero-3-PG (18:1 Lyso PE) sodium is a lysophospholipid containing oleic acid (18:1) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
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- HY-145506
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18:0 Lyso PG sodium
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Phospholipids
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1-Stearoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (18:0 Lyso PE) sodium is a lysophospholipid containing stearic acid (18:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
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- HY-145507
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1-Palmitoyl-2-hydroxy-sn-glycero-3-PG sodium; 16:0 Lyso PG; PG(16:0/0:0); 1-Hexadecanoyl-sn-glycero-3-phospho-(1'racglycerol) (sodium)
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Phospholipids
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1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (16:0 Lyso PE) sodium is a lysophospholipid containing palmitic acid (16:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
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- HY-157697
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18:0p/20:4-PE; C18(Plasm)-20:4-PE; PE(P-18:0/20:4)
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Phospholipids
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1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PE (18:0p/20:4-PE; C18(Plasm)-20:4-PE) is a plasmalogen that contains 1(Z)-octadecenoic acid and arachidonic acid (HY-109590) at the sn-1 and sn-2 positions, respectively.
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- HY-125940
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Phospholipids
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DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid that contains long-chain (16:0) palmitic acid inserted at the sn-1 and sn-2 positions, and it serves as an active component to prevent BaP molecules from entering the water subphase. DPPG sodium is used to prepare micelles, liposomes, and other types of artificial membranes that can resist damage from UV radiation [1] .
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- HY-141636
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1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine; PAPC; PC(16:0/20:4)
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Phospholipids
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1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid containing palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively, that is found in biological membranes. PAPC is oxidized in vivo, and its oxidation products are involved in chronic inflammation and vascular disease. PAPC has been used to study signaling of oxidized phospholipids. Levels of PAPC are decreased in isolated human multiple myeloma cells.
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