2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Lysophosphatidylethanolamines, egg

Lysophosphatidylethanolamines, egg  (Synonyms: Lyso-PE (egg); LPE (egg); L-α-lysophosphatidylethanolamine)

Cat. No.: HY-156041
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Lysophosphatidylethanolamine (LPE) is a naturally-occurring lysophospholipid that can be generated via deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). It increases the phosphorylation of ERK1/2 in PC12 cells, an effect that can be blocked by the MEK inhibitors U-0126 (HY-12031A) and PD 98059 (HY-12028) and the EGFR inhibitor AG-1478 (HY-13524).1 LPE also increases neurite outgrowth and expression of neurofilament M in PC12 cells. LPE inhibits the activity of phospholipase D (PLD) partially purified from cabbage.3 This product contains lysophosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 position and a hydroxy group at the sn-2 position.

For research use only. We do not sell to patients.

Lysophosphatidylethanolamines, egg Chemical Structure

Lysophosphatidylethanolamines, egg Chemical Structure

CAS No. : 97281-40-8

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5 mg USD 307 In-stock
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Lysophosphatidylethanolamines, egg Related Antibodies

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Description

Lysophosphatidylethanolamine (LPE) is a naturally-occurring lysophospholipid that can be generated via deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). It increases the phosphorylation of ERK1/2 in PC12 cells, an effect that can be blocked by the MEK inhibitors U-0126 (HY-12031A) and PD 98059 (HY-12028) and the EGFR inhibitor AG-1478 (HY-13524).1 LPE also increases neurite outgrowth and expression of neurofilament M in PC12 cells. LPE inhibits the activity of phospholipase D (PLD) partially purified from cabbage.3 This product contains lysophosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 position and a hydroxy group at the sn-2 position.

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[Lysophosphatidylethanolamines, egg]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
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Lysophosphatidylethanolamines, egg Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lysophosphatidylethanolamines, egg97281-40-8Lyso-PE (egg) LPE (egg) L-α-lysophosphatidylethanolamineEndogenous MetaboliteInhibitorinhibitorinhibit

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