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Results for "

splenic lymphocytes

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

4

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1916
    Acetylspiramycin
    2 Publications Verification

    Spiramycin B; Spiramycin II; Foromacidin B

    		 Antibiotic Bacterial Parasite Infection
    Acetylspiramycin (Spiramycin B) is an effective oral macrolide antibiotic produced by Streptomyces, It can inhibit the splenic lymphocyte transformation induced by phytohemagglutinin (PHA), LPS (HY-D1056) and antigen, reduce the procoagulant activity of macrophages, have good antibacterial effect on gram-positive bacteria, and is also an effective antigenic insect agent, which can be used to fight parasitic infection .
    Acetylspiramycin
  • HY-111827
    S-1-Propenyl-L-cysteine
    5 Publications Verification

    		 Histamine Receptor Cardiovascular Disease Others Metabolic Disease Inflammation/Immunology
    S-1-Propenyl-L-cysteine is a stereoisomer of S-allyl-l-cysteine, extracted from garlic, with immunomodulatory effects and reduces blood pressure in a hypertensive animal model . S-1-Propenyl-L-cysteine exhibits antioxidative efficacy through a NO-dependent BACH1 signaling pathway . S-1-Propenyl-L-cysteine is orally active.
    S-1-Propenyl-L-cysteine
  • HY-126813
    Concanamycin C

    		Fungal Infection
    Concanamycin C inhibits proliferation of mouse splenic lymphocytes. Concanamycin C exhibits antibiotic effects against fungal and yeast .
    Concanamycin C
  • HY-130757
    Remisporine B

    		Endogenous Metabolite Inflammation/Immunology
    Remisporine B is a polyketide, that can be isolated from Penicillium sp. ZJ-SY2. Remisporine B exhibits immunosuppressive efficacy, that inhibits concanavalin A (HY-P2149)-induced T-cell proliferation and LPS (HY-D1056)- induced B-cell proliferations of mouse splenic lymphocytes with IC50 of 30.1 µg/mL and 32.4 µg/mL .
    Remisporine B
  • HY-N12126
    Sydowinin B

    MS-347b

    		 Others Inflammation/Immunology
    Sydowinin B (MS-347b) is a active compound and can be isolated from A. sydowii. Sydowinin B shows has immunosuppressant activity .
    Sydowinin B
  • HY-W517092
    1,2,3,4,7,8,9-Heptachlorodibenzofuran

    1,2,3,4,7,8,9-HpCDF

    		 Aryl Hydrocarbon Receptor Cytochrome P450 Metabolic Disease Inflammation/Immunology
    1,2,3,4,7,8,9-Heptachlorodibenzofuran (1,2,3,4,7,8,9-HpCDF) is a compound that induces the expression of CYP1A1 and CYP1B1 genes in human peripheral blood lymphocytes, while also promoting the expression of the aryl hydrocarbon receptor repressor (AhRR). 1,2,3,4,7,8,9-Heptachlorodibenzofuran can increase ethoxyresorufin-O-deethylase (EROD) activity in isolated human peripheral blood lymphocytes in a concentration-dependent manner, which serves as a marker of CYP1A1 activity. Furthermore, 1,2,3,4,7,8,9-Heptachlorodibenzofuran exhibits immunosuppressive effects by reducing the number of splenic plaque-forming cells in mice and increasing aryl hydrocarbon hydroxylase (AHH) activity in liver microsomes of mice injected with sheep red blood cells. 1,2,3,4,7,8,9-Heptachlorodibenzofuran can be used in research in the fields of immunology, metabolic diseases, and environmental toxicology .
    1,2,3,4,7,8,9-Heptachlorodibenzofuran

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