2. PROTAC Vitamin D Related/Nuclear Receptor
  3. SNIPERs Estrogen Receptor/ERR
  4. SNIPER(ER)-110

SNIPER(ER)-110 consists of a IAP ligand and an estrogen ligand, connected by a linker. SNIPER(ER)-51 induces estrogen receptor (ER) protein degradation with DC50s of <3 nM and 7.7 nM after 4 h and 48 h, respectively.

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SNIPER(ER)-110 Chemical Structure

SNIPER(ER)-110 Chemical Structure

CAS No. : 2241690-03-7

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SNIPER(ER)-110 Related Antibodies

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Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

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Description

SNIPER(ER)-110 consists of a IAP ligand and an estrogen ligand, connected by a linker. SNIPER(ER)-51 induces estrogen receptor (ER) protein degradation with DC50s of <3 nM and 7.7 nM after 4 h and 48 h, respectively[1].

Molecular Weight

1122.39

Formula

C66H83N5O11
CAS No.
SMILES

O=C([C@H]1N(C([C@H](C2CCCCC2)NC([C@@H](NC)C)=O)=O)C[C@@H](OC3=CC=CC(OCCOCCOCCOCC(N(C)CCOC4=CC=C(/C(C5=CC=C(O)C=C5)=C(C6=CC=CC=C6)/CC)C=C4)=O)=C3)C1)N[C@@H]7CCCC8=C7C=CC=C8
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Purity & Documentation
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SNIPER(ER)-110 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SNIPER(ER)-1102241690-03-7SNIPERsEstrogen Receptor/ERRIAP-dependent Protein Eraser, Specific and Nongenetic inhibitor of apoptosis protein [IAP]-dependent Protein ErasersInhibitorinhibitorinhibit

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