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  4. Spermine NONOate

Spermine NONOate is a complex of nitric oxide (NO) with spermine and acts as a NO donor. Spermine NONOate can be used for NO aqueous solutions preparing.

For research use only. We do not sell to patients.

Spermine NONOate Chemical Structure

Spermine NONOate Chemical Structure

CAS No. : 136587-13-8

Size Price Stock Quantity
5 mg USD 68 In-stock
10 mg USD 110 In-stock
25 mg USD 220 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Spermine NONOate Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Spermine NONOate is a complex of nitric oxide (NO) with spermine and acts as a NO donor. Spermine NONOate can be used for NO aqueous solutions preparing[1].

In Vitro

Spermine NONOate has a half-life of 39 minutes and 230 minutes at 37°C and 22-25°C, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Spermine NONOate Related Antibodies
Molecular Weight

262.35

Formula

C10H26N6O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NCCCNCCCCN(CCCN)N(O)N=O
Shipping

Shipping with dry ice.
Storage

-80°C, protect from light, stored under nitrogen
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (381.17 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8117 mL 19.0585 mL 38.1170 mL
5 mM 0.7623 mL 3.8117 mL 7.6234 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 50 mg/mL (190.59 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (241 KB) HNMR (262 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.8117 mL 19.0585 mL 38.1170 mL 95.2925 mL
5 mM 0.7623 mL 3.8117 mL 7.6234 mL 19.0585 mL
10 mM 0.3812 mL 1.9059 mL 3.8117 mL 9.5293 mL
15 mM 0.2541 mL 1.2706 mL 2.5411 mL 6.3528 mL
20 mM 0.1906 mL 0.9529 mL 1.9059 mL 4.7646 mL
25 mM 0.1525 mL 0.7623 mL 1.5247 mL 3.8117 mL
30 mM 0.1271 mL 0.6353 mL 1.2706 mL 3.1764 mL
40 mM 0.0953 mL 0.4765 mL 0.9529 mL 2.3823 mL
50 mM 0.0762 mL 0.3812 mL 0.7623 mL 1.9059 mL
60 mM 0.0635 mL 0.3176 mL 0.6353 mL 1.5882 mL
80 mM 0.0476 mL 0.2382 mL 0.4765 mL 1.1912 mL
100 mM 0.0381 mL 0.1906 mL 0.3812 mL 0.9529 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Spermine NONOate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Spermine NONOate136587-13-8Othersnitric oxideNO donorInhibitorinhibitorinhibit

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