SRT 1720 hydrochloride

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SRT 1720 (x hydrochloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

SRT 1720 hydrochloride Chemical Structure

CAS No. : 1001645-58-4

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Other In-stock Forms of SRT 1720 hydrochloride:

SRT 1720 monohydrochloride

Other Forms of SRT 1720 hydrochloride:

40 Publications Citing Use of MCE SRT 1720 hydrochloride

: SRT 1720 hydrochloride purchased from MedChemExpress. Usage Cited in: Exp Eye Res. 2023 Apr 2;109464. [Abstract]; SRT1720 (1 μM; 1 h) reverses UVA (Using ultraviolet A)-inhibited expression of PGC-1α, NRF2 and TFAM in B4G12 cells.

: SRT 1720 hydrochloride purchased from MedChemExpress. Usage Cited in: Exp Eye Res. 2023 Apr 2;109464. [Abstract]; SRT1720 (1 μM; 1 h) effectively decreases the levels of cell death and ROS accumulation in the UVA (Using ultraviolet A)-irradiated B4G12 cells.

: SRT 1720 hydrochloride purchased from MedChemExpress. Usage Cited in: Hypertension. 2016 Nov;68(5):1191-1199. [Abstract]; SRT1720 rescues the downregulation of SIRT1 activity and protein expression in the aortas of KL^+/– mice. A, Representative Western blot bands of Acetyl-P53 and total P53 and the quantification of SIRT1 activity. Data are expressed as the ratio of acetyl-p53/total P53. B, Representative Western blot bands and quantitative analysis of SIRT1 protein expression in aortas. Protein expression is normalized to β-actin, and the relative expression calculated as the fold change relative

: SRT 1720 hydrochloride purchased from MedChemExpress. Usage Cited in: Toxicol Lett. 2016 Dec 15;264:1-11. [Abstract]; The HNF1α, FXR, Mrp2 and Bsep protein levels are decreased after EE administration and significantly increased by SRT1720 in a dose dependent manner, which is in accordance with the mRNA levels.

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Description	SRT 1720 (x hydrochloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
In Vitro	SRT1720 is a selective activator of SIRT1 with EC50 of 0.16 μM, more than 230 times less potent than SIRT2 and SIRT3. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. SRT 1720 hydrochloride Related Antibodies
Formula	C₂₅H₂₃N₇OS.xHCl
CAS No.	1001645-58-4
SMILES	O=C(NC1=C(C=CC=C1)C2=CN3C(SC=C3CN4CCNCC4)=N2)C5=NC6=C(N=C5)C=CC=C6.[H]Cl.[x]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (248 KB) Handling Instructions (2659 KB)