2. Cell Cycle/DNA Damage Autophagy
  3. Deubiquitinase Autophagy
  4. ST-539

ST-539 is the inhibitor for deubiquitinase USP30 with IC50 of 0.37 μM. ST-539 promotes the ubiquitination of mitochondrial proteins, and induces mitochondrial autophagy, thereby regulating mitochondrial homeostasis. ST-539 can be used in research of neurodegenerative diseases.

For research use only. We do not sell to patients.

ST-539 Chemical Structure

ST-539 Chemical Structure

CAS No. : 1040754-67-3

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ST-539 Related Antibodies

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USP1 USP2 USP7 USP8 USP30 UCHL1

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Description

ST-539 is the inhibitor for deubiquitinase USP30 with IC50 of 0.37 μM. ST-539 promotes the ubiquitination of mitochondrial proteins, and induces mitochondrial autophagy, thereby regulating mitochondrial homeostasis. ST-539 can be used in research of neurodegenerative diseases[1].

Molecular Weight

529.65

Formula

C30H31N3O4S
CAS No.
SMILES

O=C(NC1=C2C=CC=C(S(=O)(NC(C)(C)C)=O)C2=CC=C1)C(NC(C3=CC=CC=C3)=O)CC4=CC=CC=C4
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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ST-539 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ST-5391040754-67-3ST539ST 539DeubiquitinaseAutophagyDUBsParkinson’s diseasePDAlzheimer’s diseaseADInhibitorinhibitorinhibit

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