1. Cell Cycle/DNA Damage
  2. STK33
  3. STK33-IN-1

STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC50 of 7 nM.

For research use only. We do not sell to patients.

STK33-IN-1 Chemical Structure

STK33-IN-1 Chemical Structure

CAS No. : 1404437-49-5

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Description

STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC50 of 7 nM[1].

IC50 & Target

IC50: 7 nM (STK33)[1].

In Vitro

STK33-IN-1 (compound 1) is 2-fold selective for Aurora-B (AurB) versus STK33. STK33-IN-1 (compound 1) has proven unsuccessful in selectively killing KRAS-dependent cancer cell lines[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

445.52

Formula

C24H27N7O2

CAS No.
SMILES

COC(C=C1)=CC=C1N2N=CC3=CN=C(NC4=CC=C(N5CCN(C)CC5)C(OC)=C4)N=C32

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
STK33-IN-1
Cat. No.:
HY-13497
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