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Subtilisin, bacillus licheniformis  (Synonyms: Bacillopeptidaseb)

Cat. No.: HY-E70076
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Subtilisin (Compound proteinase) (EC 3.4.21.62) is a proteolytic enzyme, isolated from Bacillus licheniformis. Subtilisin (Compound proteinase) has catalytic activity in anhydrous dimethyl formamide. Subtilisin (Compound proteinase) can be used as a catalyst for easy coupling between sugars and amino acids.

For research use only. We do not sell to patients.

Subtilisin, bacillus licheniformis Chemical Structure

Subtilisin, bacillus licheniformis Chemical Structure

CAS No. : 9014-01-1

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Based on 1 publication(s) in Google Scholar

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Description

Subtilisin (Compound proteinase) (EC 3.4.21.62) is a proteolytic enzyme, isolated from Bacillus licheniformis. Subtilisin (Compound proteinase) has catalytic activity in anhydrous dimethyl formamide. Subtilisin (Compound proteinase) can be used as a catalyst for easy coupling between sugars and amino acids[1][2].

In Vitro

Subtilisin (Compound proteinase) (30 mg/mL; 2.5-7 d) selectively acylates disaccharides in anhydrous dimethylformamide[1].
Subtilisin (Compound proteinase) (1.8 g; 20-72 h) selectively acylates monosaccharides in anhydrous dimethylformamide[1].
Subtilisin (Compound proteinase) proteinase acylates D-glucose of flavanol isoquercetin (1) in the presence of activated ester trifluoroethyl butyrate (TFEB)[3].
Subtilisin (Compound proteinase) improves the solubility of protein and fatty acids, and restores polypeptides and unsaturated fatty acids[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Subtilisin (Compound proteinase) hydrolysate (the ≤1 kDa meretrix lusoria protamex hydrolysate, MLPH) (150 mg/kg and 300 mg/kg; p.o.; once daily for 6 weeks) has anti-obesity and anti-hyperglycemic effects on ob/ob mice[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

[Subtilisin, bacillus licheniformis]

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL

DMSO : 20 mg/mL (ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

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This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
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Purity & Documentation

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Subtilisin, bacillus licheniformis Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Subtilisin, bacillus licheniformis
Cat. No.:
HY-E70076
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