1. Metabolic Enzyme/Protease
  2. Phosphatase
  3. Sydowimide A

Sydowimide A is a potent inhibitor of Src homology region 2 domain-containing phosphatase-1 (SHP1), T-cell protein tyrosine phosphatase (TCPTP) and leukocyte common antigen (CD45), with IC50 values of 1.5, 2.4 and 18.83 μM, respectively.

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Sydowimide A Chemical Structure

Sydowimide A Chemical Structure

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Based on 1 publication(s) in Google Scholar

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Description

Sydowimide A is a potent inhibitor of Src homology region 2 domain-containing phosphatase-1 (SHP1), T-cell protein tyrosine phosphatase (TCPTP) and leukocyte common antigen (CD45), with IC50 values of 1.5, 2.4 and 18.83 μM, respectively[1].

Molecular Weight

288.30

Formula

C15H16N2O4

SMILES

COC(/C(N1C(CC(C1=O)C)=O)=C\NC2=CC=CC=C2)=O

Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Sydowimide A
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HY-N12613
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