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  4. TAT-GluN2B

TAT-GluN2B, a synthetic peptide, is a negative control of Tat-GluN2BCTM (Neuroprotective Agent).

For research use only. We do not sell to patients.

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TAT-GluN2B Chemical Structure

TAT-GluN2B Chemical Structure

CAS No. : 1587636-62-1

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Description

TAT-GluN2B, a synthetic peptide, is a negative control of Tat-GluN2BCTM (Neuroprotective Agent)[1].

In Vitro

TAT-GluN2BCTM (25 µM, neuronal culture) results in significant reduction of DAPK1 following NMDA treatment, but TAT-GluN2B does not affect DAPK1 level[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

TAT-GluN2BCTM (10 mg/kg, i.v.) specifically knocks down DAPK1 in ischemic brain areas and reduces neuronal damage in the MCAo model of focal ischemia in rats, but TAT-GluN2B does not change DAPK1 levels in the brain tissues of either ischemic or contralateral side[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

3269.78

Formula

C137H242N62O32

CAS No.
Sequence

Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys-Lys-Asn-Arg-Asn-Lys-Leu-Arg-Arg-Gln-His-Ser-Tyr

Sequence Shortening

YGRKKRRQRRRKKNRNKLRRQHSY

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
TAT-GluN2B
Cat. No.:
HY-P5281
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