1. Metabolic Enzyme/Protease
  2. Phosphatase
  3. TCS 401 free base

TCS 401 free base is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B).

For research use only. We do not sell to patients.

TCS 401 free base Chemical Structure

TCS 401 free base Chemical Structure

CAS No. : 243967-42-2

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Top Publications Citing Use of Products

    TCS 401 free base purchased from MedChemExpress. Usage Cited in: J Tissue Eng Regen Med. 2020 Apr;14(4):575-587.  [Abstract]

    The activation of Src by treatment with the 152RM peptide is reversed by pretreatment with the PTP1B inhibitor TCS-401, and the increased phosphorylation of β-catenin Y654 by treatment with the 152RM peptide is reduced by pretreatment with the Src inhibitor bosutinib.
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    Description

    TCS 401 free base is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B).

    Molecular Weight

    270.26

    Formula

    C10H10N2O5S

    CAS No.
    SMILES

    O=C(C(NC1=C(C(O)=O)C(CCNC2)=C2S1)=O)O

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.

    Purity & Documentation
    References
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    TCS 401 free base Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Product Name:
    TCS 401 free base
    Cat. No.:
    HY-12312A
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