2. Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  3. JAK
  4. Ten01

Ten01 has 5.0 nM activity against JAK1 kinase.

For research use only. We do not sell to patients.

Ten01 Chemical Structure

Ten01 Chemical Structure

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Ten01 Related Antibodies

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JAK1 JAK2 JAK3 Tyk2 JAK

  • Biological Activity

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Description

Ten01 has 5.0 nM activity against JAK1 kinase.

IC50 & Target

JAK1

5 nM (IC50)

Molecular Weight

422.37

Formula

C18H20F6N4O
SMILES

FC(F)(F)C1=CN=C(NC=C2)C2=C1C[C@H]3CN(C(NCC(F)(F)F)=O)C[C@@H]3CC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Ten01 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ten01Ten 01Ten-01JAKJanus kinaseInhibitorinhibitorinhibit

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Product Name:
Ten01
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HY-139649
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