Terfenadine (Standard)

Cat. No.: HY-B1193R Purity: ≥98%: FAQs
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Terfenadine (Standard) is the analytical standard of Terfenadine. This product is intended for research and analytical applications. Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.

For research use only. We do not sell to patients.

Terfenadine (Standard) Chemical Structure

CAS No. : 50679-08-8

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Description	Terfenadine (Standard) is the analytical standard of Terfenadine . This product is intended for research and analytical applications. Terfenadine ((±)-Terfenadine ) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine , an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.
Molecular Weight	471.67
Formula	C₃₂H₄₁NO₂
CAS No.	50679-08-8
SMILES	OC(C1=CC=C(C(C)(C)C)C=C1)CCCN2CCC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)CC2
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Terfenadine (Standard) Related Classifications

Molarity Calculator
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Terfenadine (Standard)50679-08-8Potassium ChannelHistamine ReceptorNa+/Ca2+ ExchangerCaspaseApoptosisKcsAInhibitorinhibitorinhibit

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Terfenadine (Standard)

Product Information

Purity & Documentation

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Terfenadine (Standard) Related Classifications

Molarity Calculator

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