2. Metabolic Enzyme/Protease
  3. Tryptophan Hydroxylase
  4. TPH1-IN-1

TPH1-IN-1 (compound 40) is a xanthine derivative and an inhibitor of tryptophan hydroxylase TPH1 (IC50: 110.1 nM). TPH1-IN-1 has good in vitro activity and liver microsome stability, and effectively inhibits adipocyte differentiation of T3-L1 cells.

For research use only. We do not sell to patients.

TPH1-IN-1 Chemical Structure

TPH1-IN-1 Chemical Structure

CAS No. : 3040015-86-6

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TPH1-IN-1 Related Antibodies

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Description

TPH1-IN-1 (compound 40) is a xanthine derivative and an inhibitor of tryptophan hydroxylase TPH1 (IC50: 110.1 nM). TPH1-IN-1 has good in vitro activity and liver microsome stability, and effectively inhibits adipocyte differentiation of T3-L1 cells[1].

IC50 & Target

IC50: 110.1 nM (TPH1)[1]
Molecular Weight

450.47

Formula

C21H18N6O4S
CAS No.
SMILES

OC1=CC=C(C(CN2C(C(NC(N3CC)=O)=O)=C3N=C2CC4=CN5C(SC=C5)=N4)=O)C=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TPH1-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TPH1-IN-13040015-86-6Tryptophan HydroxylaseFatty liverObesityTPH inhibitorXanthineInhibitorinhibitorinhibit

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