Trisodium phosphate dodecahydrate  (Synonyms: Phosphoric acid, sodium salt, hydrate (1:3:12))

Trisodium phosphate dodecahydrate is a corrosion inhibitor for iron in 0.1 M NaClO4, in both aerated and deaerated solutions. Trisodium phosphate dodecahydrate can be used as an excipient, such as pH regulator, buffer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs^[1][2].

380.18

H₂₄Na₃₆O₁₆P

10101-89-0

Solid

White to off-white

[Na].O=P(O)(O)O.O

Room temperature in continental US; may vary elsewhere.

Store at room temperature 3 years

• [1]. Armstrong R D, et al. Behaviour of sodium silicate and sodium phosphate (tribasic) as corrosion inhibitors for iron[J]. Journal of applied electrochemistry, 1994, 24: 1244-1248.

  [2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.  [Content Brief]