2. Anti-infection
  3. Bacterial
  4. Tuberculosis inhibitor 1

Tuberculosis inhibitor 1 is a potent and non-cytotoxic trypanosoma brucei growth inhibitor with an EC50 of 5 nM.

For research use only. We do not sell to patients.

Tuberculosis inhibitor 1 Chemical Structure

Tuberculosis inhibitor 1 Chemical Structure

CAS No. : 2230810-28-1

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Tuberculosis inhibitor 1 Related Antibodies

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Description

Tuberculosis inhibitor 1 is a potent and non-cytotoxic trypanosoma brucei growth inhibitor with an EC50 of 5 nM[1].

IC50 & Target

EC50: 5 nM (Trypanosoma brucei)[1]
Cellular Effect
Cell Line Type Value Description References
HeLa CC50
> 25000 nM
Compound: 34, Epimeric mixture
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by celltiter glo assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by celltiter glo assay
[PMID: 30482621]
In Vitro

Tuberculosis inhibitor 1 is selective over other parasites, such as Trypanosoma cruzi and Plasmodium falciparum (T. cruzi EC50 8120 nM, P. falciparum EC50 3624 nM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tuberculosis inhibitor 1 Related Antibodies
Molecular Weight

563.69

Formula

C34H37N5O3
CAS No.
SMILES

O=C(CC1=C(C)NC2=C1C=C(OC)C=C2)N(CCN(CC3CCOC3)C4)C4C5=NC=C(N5)C6=CC(C=CC=C7)=C7C=C6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Tuberculosis inhibitor 1 Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tuberculosis inhibitor 12230810-28-1Tuberculosis inhibitor1Tuberculosis inhibitor-1BacterialInhibitorinhibitorinhibit

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Tuberculosis inhibitor 1
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HY-119938
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