1. Cell Cycle/DNA Damage Cytoskeleton
  2. Microtubule/Tubulin
  3. Tubulin inhibitor 12

Tubulin inhibitor 12 (Hit 9) is a novel tubulin inhibitor (IC50=25.3 μM). Tubulin inhibitor 12 shows anti-tumor activity and anti-proliferative activity.

For research use only. We do not sell to patients.

Tubulin inhibitor 12 Chemical Structure

Tubulin inhibitor 12 Chemical Structure

CAS No. : 92575-00-3

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Description

Tubulin inhibitor 12 (Hit 9) is a novel tubulin inhibitor (IC50=25.3 μM). Tubulin inhibitor 12 shows anti-tumor activity and anti-proliferative activity[1].

In Vitro

Tubulin inhibitor 12 (0-100 μM; 72 h) shows moderate and broad-spectrum anti-proliferative activity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: HepG2, A549, and HCT116 cells
Concentration: 0-100 μM
Incubation Time: 72 hours
Result: Showed IC50 values of 49.13, 52.84, and 70.10 μM for HepG2, A549, and HCT116 cells, respectively.
Molecular Weight

352.43

Formula

C24H20N2O

CAS No.
SMILES

CN(C(C1=CC(C2=CC=CC=C2)=NC3=CC=CC=C31)=O)CC4=CC=CC=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Tubulin inhibitor 12
Cat. No.:
HY-143250
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