2. Cell Cycle/DNA Damage Cytoskeleton
  3. Microtubule/Tubulin
  4. Tubulin polymerization-IN-19

Tubulin polymerization-IN-19 (compound 4) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-20 has the potential for the research of breast cancers and chemoresistant colon cancers.

For research use only. We do not sell to patients.

Tubulin polymerization-IN-19 Chemical Structure

Tubulin polymerization-IN-19 Chemical Structure

CAS No. : 2340345-85-7

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Tubulin polymerization-IN-19 Related Antibodies

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Description

Tubulin polymerization-IN-19 (compound 4) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-20 has the potential for the research of breast cancers and chemoresistant colon cancers[1].

Cellular Effect
Cell Line Type Value Description References
HT-29 IC50
0.022 μM
Compound: 5b
Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by alamar blue assay
Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by alamar blue assay
[PMID: 31954879]
MCF7 IC50
0.015 μM
Compound: 5b
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by alamar blue assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by alamar blue assay
[PMID: 31954879]
Molecular Weight

419.47

Formula

C25H25NO5
CAS No.
SMILES

COC1=CC(N2C([C@H]([C@@H]2C3=CC=C(C=C3)OC)C4=CC=CC=C4)=O)=CC(OC)=C1OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Tubulin polymerization-IN-19 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tubulin polymerization-IN-192340345-85-7Microtubule/Tubulintubulin polymerizationbreastchemoresistant colonInhibitorinhibitorinhibit

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