Uncargenin C

Cat. No.: HY-N1112: FAQs
Data Sheet Handling Instructions

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Uncargenin C is a triterpenoid, which can be isolated from Uncaria rhychophyllo Miq. Jacks. The intermediate of Uncargenin C has anti-leukemia activity, but not itself.

For research use only. We do not sell to patients.

Uncargenin C Chemical Structure

CAS No. : 152243-70-4

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1 mg	USD 480	Ask For Quote & Lead Time
5 mg	USD 1202	Ask For Quote & Lead Time

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Description

Uncargenin C is a triterpenoid, which can be isolated from Uncaria rhychophyllo Miq. Jacks. The intermediate of Uncargenin C has anti-leukemia activity, but not itself^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	1.4 μM Compound: 7	Inhibition of TNF-alpha-induced NFkappaB activation in human HepG2 cells after 1 hr by luciferase reporter assay Inhibition of TNF-alpha-induced NFkappaB activation in human HepG2 cells after 1 hr by luciferase reporter assay	[PMID: 21870831]

Molecular Weight

488.70

Formula

C₃₀H₄₈O₅

CAS No.

152243-70-4

SMILES

C[C@]12[C@]3(C([C@@]4([H])[C@@](CC3)(CCC(C)(C4)C)C(O)=O)=CC[C@]1([H])[C@@]5([C@@]([C@@](C)([C@H](CC5)O)CO)([H])[C@@H](C2)O)C)C

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. WU et al. Triterpenoids from Uncaria rhynchophylla[J]. Plant Diversity, 1995, 17(02): 1.

[2]. Berger M, Knittl-Frank C, Bauer S, et al. Application of relay C− H oxidation logic to polyhydroxylated oleanane triterpenoids[J]. Chem, 2020, 6(5): 1183-1189.

Uncargenin C Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Uncargenin C152243-70-4OtherstriterpenoidUncaria rhychophylloanti-leukemiaInhibitorinhibitorinhibit

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