2. Cell Cycle/DNA Damage
  3. Deubiquitinase
  4. USP1-IN-10

USP1-IN-10 (compound 2) is a potent tricyclic USP1 inhibitor with an IC50 of 7.6 nM. USP1-IN-10 inhibits MDA-MB-436 viability (IC50=21.58 nM). USP1-IN-10 has the potential for cancers research.

For research use only. We do not sell to patients.

USP1-IN-10 Chemical Structure

USP1-IN-10 Chemical Structure

CAS No. : 2857051-98-8

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USP1-IN-10 Related Antibodies

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USP1 USP2 USP7 USP8 USP30 UCHL1

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Description

USP1-IN-10 (compound 2) is a potent tricyclic USP1 inhibitor with an IC50 of 7.6 nM. USP1-IN-10 inhibits MDA-MB-436 viability (IC50=21.58 nM). USP1-IN-10 has the potential for cancers research[1].

IC50 & Target[1]

USP1

7.6 nM (IC50)

Molecular Weight

545.52

Formula

C27H22F3N9O
CAS No.
SMILES

COC(N=CN=C1C2CC2)=C1C3=NC=C4C(N(CC5=CC=C(C6=NC(C(F)(F)F)=CN6C)C=C5)C7=CN=CN74)=N3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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USP1-IN-10 Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

USP1-IN-102857051-98-8DeubiquitinaseDUBsTricyclicMDA-MB-436cancerInhibitorinhibitorinhibit

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