1. Cell Cycle/DNA Damage
  2. Deubiquitinase
  3. USP7/USP47 inhibitor 1

USP7/USP47 inhibitor 1 (compound 2) is an inhibitor of USP47, with an EC50 of 14 μM. USP7/USP47 inhibitor 1 has an EC50 of >31.6 μM for USP7. USP7/USP47 inhibitor 1 can be used for cancer research.

For research use only. We do not sell to patients.

USP7/USP47 inhibitor 1 Chemical Structure

USP7/USP47 inhibitor 1 Chemical Structure

CAS No. : 90680-28-7

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Description

USP7/USP47 inhibitor 1 (compound 2) is an inhibitor of USP47, with an EC50 of 14 μM. USP7/USP47 inhibitor 1 has an EC50 of >31.6 μM for USP7. USP7/USP47 inhibitor 1 can be used for cancer research[1].

IC50 & Target

IC50: 14 ± 0.4 μM (USP47); >31.6 μM (USP7)[1]

Cellular Effect
Cell Line Type Value Description References
Sf9 IC50
> 31.6 μM
Compound: 2
Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assay
Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assay
[PMID: 24900381]
Molecular Weight

279.33

Formula

C12H9NO3S2

CAS No.
SMILES

CC(C1=CC([N+]([O-])=O)=C(SC2=CC=CC=C2)S1)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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USP7/USP47 inhibitor 1
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HY-111166
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