2. Metabolic Enzyme/Protease NF-κB
  3. MALT1
  4. Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone

Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone is a potent MALT1 inhibitor. Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone inhibits cell proliferation and migration. Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone shows anticancer activity.

For research use only. We do not sell to patients.

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Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone Chemical Structure

Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone Chemical Structure

CAS No. : 1926163-57-6

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Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone Related Antibodies

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Description

Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone is a potent MALT1 inhibitor. Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone inhibits cell proliferation and migration. Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone shows anticancer activity[1].

IC50 & Target

MALT1[1]
In Vitro

Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone (75 mol/L; 6, 12, 24, 36, and 48 h) inhibits the proliferation and migration of OCI-LY10 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone Related Antibodies

Cell Proliferation Assay[1]

Cell Line: OCI-LY10 cells
Concentration: 75 mol/L
Incubation Time: 6, 12, 24, 36, and 48 h
Result: Inhibited the proliferation and migration of OCI-LY10 cells.
In Vivo

Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone (37.5 M*0.2 mL; every other day for 12 days) inhibits the growth of the tumor in mouse[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 4-6 weeks, 16-20 g, Female BALB/c nude mice (OCI-LY10 cells)[1]
Dosage: 37.5 M*0.2 mL
Administration: Every other day for 12 days
Result: Inhibited the growth of the xenografts and decreased the expression of P65.
Molecular Weight

676.78

Formula

C31H49FN10O6
CAS No.
Sequence

Z-Val-Arg-Pro-{DL-Arg}-{Fluoromethylketone}
Sequence Shortening

Z-VRP-{DL-Arg}-{Fluoromethylketone}
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone1926163-57-6MALT1mucosa associated lymphoid tissue lymphoma translocation gene 1anticancerOCI-LY10 cellsproliferationmigrationP65DLBCLInhibitorinhibitorinhibit

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