2. Protein Tyrosine Kinase/RTK
  3. VEGFR
  4. VEGFR-2-IN-17

VEGFR-2-IN-17 (Compound 15a) is a potent VEGFR-2 inhibitor with an IC50 of 67.25 nM. VEGFR-2-IN-17 shows antitumor activities.

For research use only. We do not sell to patients.

VEGFR-2-IN-17 Chemical Structure

VEGFR-2-IN-17 Chemical Structure

CAS No. : 3033041-34-5

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VEGFR-2-IN-17 Related Antibodies

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Description

VEGFR-2-IN-17 (Compound 15a) is a potent VEGFR-2 inhibitor with an IC50 of 67.25 nM. VEGFR-2-IN-17 shows antitumor activities[1].

IC50 & Target

VEGFR2

67.25 nM (IC50)

In Vitro

VEGFR-2-IN-17 (Compound 15a) shows antiproliferative activities with IC50 values of 34.59 ± 2.82, 30.28 ± 2.56, 47.10 ± 3.59 and 250.33 ± 2.51 µM against HepG2, PC3, MCF-7 and WI-38 cells, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

VEGFR-2-IN-17 Related Antibodies
Molecular Weight

375.81

Formula

C21H14ClN3O2
CAS No.
SMILES

O=C(NC1=CC=C(OC2=C3C=CC=CC3=NC(Cl)=N2)C=C1)C4=CC=CC=C4
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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VEGFR-2-IN-17 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VEGFR-2-IN-173033041-34-5VEGFRVascular endothelial growth factor receptorHepG2PC3MCF-7antitumorInhibitorinhibitorinhibit

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