2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Calcium Channel
  4. Verticilide

Verticilide is a ryanodine-binding inhibitor and inhibits ryanodine binding to ryanodine receptors in the cockroach at an IC50 value of 4.2 ?μM (whereas inhibition against mouse ryanodine receptors was weak (IC50=53.9?μM)).

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Verticilide Chemical Structure

Verticilide Chemical Structure

CAS No. : 693778-57-3

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Other Forms of Verticilide:

Verticilide Related Antibodies

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

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Description

Verticilide is a ryanodine-binding inhibitor and inhibits ryanodine binding to ryanodine receptors in the cockroach at an IC50 value of 4.2 ?μM (whereas inhibition against mouse ryanodine receptors was weak (IC50=53.9?μM))[1].

Molecular Weight

853.09

Formula

C44H76N4O12
CAS No.
Sequence

cyclo[N(Me)Ala-D-ONle(Me)-N(Me)Ala-D-ONle(Me)-N(Me)Ala-D-ONle(Me)-N(Me)Ala-D-ONle(Me)]
SMILES

CCCCC[C@@H](OC([C@@H](N(C([C@H](OC([C@@H](N(C1=O)C)C)=O)CCCCC)=O)C)C)=O)C(N([C@H](C(O[C@@H](C(N([C@H](C(O[C@@H]1CCCCC)=O)C)C)=O)CCCCC)=O)C)C)=O
Structure Classification
Initial Source

Verticillium sp. FKI-1033
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Verticilide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Verticilide693778-57-3Calcium ChannelCa2+ channelsCa channelsInhibitorinhibitorinhibit

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