2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. VH032-PEG2-NH-BOC

VH032-PEG2-NH-BOC is a Boc-modified VH032 (HY-120217) that serves as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-PEG2-NH-BOC will remove the protecting group under acidic conditions and be directly used for PROTAC molecule synthesis. VH032-PEG2-NH-BOC is a key intermediate in the synthesis of PROTAC based on VHL ligand.

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VH032-PEG2-NH-BOC Chemical Structure

VH032-PEG2-NH-BOC Chemical Structure

CAS No. : 2162120-75-2

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VH032-PEG2-NH-BOC Related Antibodies

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View All E3 Ligase Ligand-Linker Conjugates Isoform Specific Products:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

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Description

VH032-PEG2-NH-BOC is a Boc-modified VH032 (HY-120217) that serves as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-PEG2-NH-BOC will remove the protecting group under acidic conditions and be directly used for PROTAC molecule synthesis. VH032-PEG2-NH-BOC is a key intermediate in the synthesis of PROTAC based on VHL ligand.

Molecular Weight

675.84

Formula

C33H49N5O8S
CAS No.
SMILES

O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(COCCOCCNC(OC(C)(C)C)=O)=O)=O)C[C@H](O)C3
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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VH032-PEG2-NH-BOC Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VH032-PEG2-NH-BOC2162120-75-2E3 Ligase Ligand-Linker ConjugatesLigands for E3 LigaseInhibitorinhibitorinhibit

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