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  4. Vinclozolin M2

Vinclozolin M2 is an active metabolite of vinclozolin. It is formed from vinclozolin by successive esterase activity and decarboxylation of vinclozolin in C. elegans and by decarboxylation in human liver microsomes. Vinclozolin M2 is an antagonist of the mineralocorticoid receptor (IC50=1,400 nM) and androgen receptor (IC50=0.17 nM) in reporter assays using MCF-7 cells.

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Vinclozolin M2 Chemical Structure

Vinclozolin M2 Chemical Structure

CAS No. : 83792-61-4

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Vinclozolin M2 Related Antibodies

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Description

Vinclozolin M2 is an active metabolite of vinclozolin. It is formed from vinclozolin by successive esterase activity and decarboxylation of vinclozolin in C. elegans and by decarboxylation in human liver microsomes. Vinclozolin M2 is an antagonist of the mineralocorticoid receptor (IC50=1,400 nM) and androgen receptor (IC50=0.17 nM) in reporter assays using MCF-7 cells.

Molecular Weight

260.12

Formula

C11H11Cl2NO2
CAS No.
SMILES

C=CC(C)(O)C(NC1=CC(Cl)=CC(Cl)=C1)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Vinclozolin M2 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vinclozolin M283792-61-4Vinclozolin M 2Vinclozolin M-2ParasiteInhibitorinhibitorinhibit

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